Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Carol A. Pollock"'
Autor:
Anthony J. Gill, Martin E. Gosnell, Saabah B. Mahbub, Ewa M. Goldys, Jared M. Campbell, Abbas Habibalahi, Muh Geot Wong, Long T. Nguyen, Carol A. Pollock, Ayad G. Anwer, Uzair M. Qadri, Angela Chou, Sonia Saad
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Optimally preserved urinary exfoliated renal proximal tubule cells were assessed by multispectral imaging of cell autofluorescence. We demonstrated different multispectral autofluorescence signals in such cells extracted from the urine of patients wi
Autor:
Benjamin P. Larkin, Rosy Wang, Miao Hou, Long T. Nguyen, Sonia Saad, Hui Chen, Carol A. Pollock, Sarah J. Glastras
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248854 (2021)
PLoS ONE
PLoS ONE
Background Maternal high fat diet (HFD) promotes chronic kidney disease (CKD) in offspring. This is in accordance with the theory of fetal programming, which suggests adverse conditions occurring in utero predispose offspring to chronic conditions la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e18bf900265dfba64336caadbc7034b
https://hdl.handle.net/10453/152976
https://hdl.handle.net/10453/152976
Autor:
Carol A. Pollock, Rosy Wang, Wolfgang Jarolimek, Angela Chou, Anthony J. Gill, Ying Shi, Sonia Saad, Long T. Nguyen, Yimin Yao
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Calcineurin inhibitors, such as Cyclosporin (CsA), are the mainstay of anti-rejection therapy in solid organ transplants but can paradoxically induce progressive nephropathy characterised by renal dysfunction and interstitial fibrosis. Lysyl oxidases
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Receptor-interacting protein kinase-3 (RIPK3) is a multifunctional regulator of cell death and inflammation. RIPK3 controls cellular signalling through the formation of the domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome, w
Autor:
Amgad Zaky, Sonia Saad, Wolfgang Jarolimek, Stefanie Stangenberg, Muh Geot Wong, Carol A. Pollock, Anthony J. Gill, May Yw Wong, Heidi Schilter
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0234617 (2020)
PLoS ONE, Vol 15, Iss 6, p e0234617 (2020)
Semicarbazide-sensitive amine oxidase (SSAO) is an enzyme with a unique dual function in controlling inflammation as well as reactive oxygen species (ROS) generation. We have demonstrated benefit of SSAO inhibition in acute kidney fibrosis. However t
Autor:
Uzair M. Qadri, Angela Chou, Jared M. Campbell, Abbas Habibalahi, Ayad G. Anwer, Sonia Saad, Long T. Nguyen, Muh Geot Wong, Ewa M. Goldys, Martin E. Gosnell, Anthony J. Gill, Saabah B. Mahbub, Carol A. Pollock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Autor:
Yeoungjee Cho, Muh Geot Wong, David W. Johnson, Bruce A. Cooper, Nicole M. Isbel, Elaine M. Pascoe, Carolyn van Eps, Scott B. Campbell, Carmel M. Hawley, David Harris, Andrea K. Viecelli, Isabelle Ethier, Carol A. Pollock
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0242254 (2020)
PLoS ONE, Vol 15, Iss 11, p e0242254 (2020)
BackgroundResidual kidney function (RKF) is associated with improved survival and quality of life in dialysis patients. Previous studies have suggested that initiation of peritoneal dialysis (PD) may slow RKF decline compared to the pre-dialysis peri
Autor:
Anthony J. Gill, Heidi Schilter, Stefanie Stangenberg, Amgad Zaky, Sonia Saad, Carol A. Pollock, Muh Geot Wong
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Diabetic nephropathy is characterised by the excessive amount of extracellular matrix in glomeruli and tubulointerstitial space. Lysyl oxidase-like 2 (LOXL2) is elevated in renal fibrosis and known to play key roles in ECM stabilisation by facilitati
Autor:
Ewa M. Goldys, Yik Lung Chan, Sonia Saad, Amgad Zaky, Hui Chen, Razia Zakarya, Carol A. Pollock, Rachana Santiyanont, Suporn Sukjamnong, Ayad G. Anwer, Brian G. Oliver
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
To investigate the effect of maternal MitoQ treatment on renal disorders caused by maternal cigarette smoke exposure (SE). We have demonstrated that maternal SE during pregnancy increases the risk of developing chronic kidney disease (CKD) in adult o
The KCa3.1 blocker TRAM34 reverses renal damage in a mouse model of established diabetic nephropathy
Autor:
Xin-Ming Chen, Carol A. Pollock, Chunling Huang, Yongli Zhao, Hao Yi, Ling Zhang, Jason Chen, Ying Shi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0192800 (2018)
PLoS ONE, Vol 13, Iss 2, p e0192800 (2018)
Despite optimal control of hyperglycaemia, hypertension, and dyslipidaemia, the number of patients with diabetic nephropathy (DN) continues to grow. Strategies to target various signaling pathways to prevent DN have been intensively investigated in a