Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jan Tavernier"'
Autor:
Shengru Pang, Anje Cauwels, Sandra Van Lint, Marco Prinz, Niko Kley, Elke Rogge, Jan Tavernier, Bram Van Den Eeckhout, Gilles Uzé, Annick Verhee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11, ⟨10.1038/s41598-021-00891-6⟩
SCIENTIFIC REPORTS
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11, ⟨10.1038/s41598-021-00891-6⟩
SCIENTIFIC REPORTS
Type I Interferon (IFN) was the very first drug approved for the treatment of Multiple Sclerosis (MS), and is still frequently used as a first line therapy. However, systemic IFN also causes considerable side effects, affecting therapy adherence and
Autor:
David J. Pagliarini, Kritika Bhalla, Karen Rosier, Brendan J. Floyd, Rudy Van Coster, John W.M. Creemers, Irma Lemmens, Edrees H. Rashan, Maxime Verschoore, Benjamin F. Cravatt, Matteo Dal Peraro, Katlijn Vints, Luc Régal, Joél Smet, Laetitia Aerts, Arnaud Vanlander, Yenthe Monnens, Natalia V. Gounko, Craig A. Bingman, Jan Tavernier, Molly T. McDevitt, Maria J. Marcaida
Publikováno v:
iScience
ISCIENCE
iScience, Vol 24, Iss 12, Pp 103460-(2021)
ISCIENCE
iScience, Vol 24, Iss 12, Pp 103460-(2021)
Summary Deficiency of the serine hydrolase prolyl endopeptidase-like (PREPL) causes a recessive metabolic disorder characterized by neonatal hypotonia, feeding difficulties, and growth hormone deficiency. The pathophysiology of PREPL deficiency and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d632ef57ff0933bdaa806f554927a20
https://hdl.handle.net/20.500.14017/c7bfdaf7-1b1c-4a72-9f07-6f40a36a6606
https://hdl.handle.net/20.500.14017/c7bfdaf7-1b1c-4a72-9f07-6f40a36a6606
Autor:
Geert van Loo, Rudi Beyaert, Kelly Van Looveren, Roman Vangoitsenhoven, Tineke Vanderhaeghen, Bart Van der Schueren, Jan Tavernier, Toshinori Nakayama, Sylviane Dewaele, Charlotte Wallaeys, Steven Timmermans, Claude Libert, Leen Catrysse, Lise Van Wyngene, Melanie Eggermont, Ioanna Petta, Katrien Corbeels, Jolien Vandewalle, Karolien De Bosscher
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102790-(2021)
ISCIENCE
iScience
ISCIENCE
iScience
Summary The hypothalamic-pituitary-adrenal (HPA) axis forms a complex neuroendocrine system that regulates the body’s response to stress such as starvation. In contrast with the glucocorticoid receptor (GR), Zinc finger and BTB domain containing 32
Autor:
Sudharshan Rangarajan, Philipp Trepte, Luke Lambourne, Soon Gang Choi, Patricia Cassonnet, Irma Lemmens, Javier De Las Rivas, Tong Hao, Wenting Bian, Marc Vidal, Eloi P. Coutant, Pierre-Olivier Vidalain, David E. Hill, Caroline Demeret, Mélanie Dos Santos, Michael A. Calderwood, Louis Jones, Julien Olivet, Kerstin Spirohn, Sylvie van der Werf, Erich E. Wanker, Jan Tavernier, Yves Jacob, Yves L. Janin, Jean-Claude Twizere, Katja Luck
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3907. ⟨10.1038/s41467-019-11809-2⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 2019, 10 (1), pp.3907. ⟨10.1038/s41467-019-11809-2⟩
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3907. ⟨10.1038/s41467-019-11809-2⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 2019, 10 (1), pp.3907. ⟨10.1038/s41467-019-11809-2⟩
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
© The Author(s) 2019.
Complementary assays are required to comprehensively map complex biological entities such as genomes, proteomes and interactome networks. However, how various assays can be optimally combined to approach completeness while
Complementary assays are required to comprehensively map complex biological entities such as genomes, proteomes and interactome networks. However, how various assays can be optimally combined to approach completeness while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f2bbfd1a267b0f3742fc7c507d912a
https://hal-pasteur.archives-ouvertes.fr/pasteur-02322138
https://hal-pasteur.archives-ouvertes.fr/pasteur-02322138
Autor:
Jan Tavernier, Kenny Roose, Lien Van Hoecke, Alexander Van Parys, Xavier Saelens, Stefaan De Koker, Sandra Van Lint, Johan Grooten, Peter Vandenabeele
Publikováno v:
Cell Stress
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
NATURE COMMUNICATIONS
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
NATURE COMMUNICATIONS
Cancer immunotherapy can induce durable antitumor responses. However, many patients poorly respond to such therapies. Here we describe a generic antitumor therapy that is based on the intratumor delivery of mRNA that codes for the necroptosis executi
Autor:
Lode De Cauwer, Claude Libert, Sam Lievens, Jonathan Thommis, Nadia Bougarne, Jan Tavernier, Marlies Ballegeer, Sofie Desmet, Ioanna Petta, Lien Dejager, Sofie Vandevyver, Karolien De Bosscher, Jolien Vandewalle
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
SCIENTIFIC REPORTS
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
SCIENTIFIC REPORTS
The transcriptional activity of the glucocorticoid receptor (GR) is co-determined by its ability to recruit a vast and varying number of cofactors. We here identify Striatin-3 (STRN3) as a novel interaction partner of GR that interferes with GR’s l
Autor:
K. De Bosscher, Jonathan Thommis, Marnik Vuylsteke, Nadia Bougarne, Sofie Desmet, René Houtman, Dariusz Ratman, Jan Tavernier, L. De Cauwer, L. Van de Moortel
Publikováno v:
SCIENTIFIC REPORTS
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
The glucocorticoid receptor (GR) is a transcription factor of which the underlying gene regulatory mechanisms are complex and incompletely understood. The non-steroidal anti-inflammatory Compound A (CpdA), a selective GR modulating compound in variou
Autor:
Dries Van Rompaey, Ann Dansercoer, Frank Peelman, Guy Lippens, Rudi Beyaert, Juan José Marín López, Isabel Vandenberghe, Kenneth Verstraete, Jan Tavernier, Harald Braun, Hans De Winter, Savvas N. Savvides, Bart N. Lambrecht, Kris Pauwels, Hamida Hammad
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), 17 p. ⟨10.1038/ncomms14937⟩
Nature Communications, 2017, 8 (1), 17 p. ⟨10.1038/ncomms14937⟩
Nature Communications (8), 17 p.. (2017)
Nature communications
NATURE COMMUNICATIONS
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications, Nature Publishing Group, 2017, 8 (1), 17 p. ⟨10.1038/ncomms14937⟩
Nature Communications, 2017, 8 (1), 17 p. ⟨10.1038/ncomms14937⟩
Nature Communications (8), 17 p.. (2017)
Nature communications
NATURE COMMUNICATIONS
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
The pro-inflammatory cytokine thymic stromal lymphopoietin (TSLP) is pivotal to the pathophysiology of widespread allergic diseases mediated by type 2 helper T cell (Th2) responses, including asthma and atopic dermatitis. The emergence of human TSLP
Autor:
Serge Van Calenbergh, Annick Verhee, Leentje De Ceuninck, Kevin Titeca, Kris Gevaert, Eva Cloots, Jan Tavernier, Sam Lievens, Delphine De Sutter, Emmy Van Quickelberghe, Sven Eyckerman, Evy Timmerman, Noortje Samyn
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
NATURE COMMUNICATIONS
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Cell lysis is an inevitable step in classical mass spectrometry–based strategies to analyse protein complexes. Complementary lysis conditions, in situ cross-linking strategies and proximal labelling techniques are currently used to reduce lysis eff
Autor:
Geertrui Denecker, Ali A. Bahar, Wim Declercq, Michael Devos, Sam Lievens, Marc Bracke, Dorien Clarisse, Valerie Gossye, Wim Vanden Berghe, Guy Haegeman, Nadia Bougarne, Sofie Desmet, Kris Gevaert, Jan Tavernier, Bart Ruttens, Zuzanna Drebert, Ruben Hoya-Arias, Ilse M. Beck, Karolien De Bosscher
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e69115 (2013)
PLOS ONE
PLoS ONE, Vol 8, Iss 7, p e69115 (2013)
PLOS ONE
Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-kappa B-mediated gene expression. However, the monomeric Compound A-activated GR is unable to trigger