Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jan Tavernier"'
Autor:
Jan Tavernier, Dorien Clarisse, Karlien Van Wesemael, Ilse M. Beck, Fritz Offner, Karolien De Bosscher
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 5, p e0197000 (2018)
PLOS ONE
PLoS ONE, Vol 13, Iss 5, p e0197000 (2018)
PLOS ONE
Glucocorticoids (GCs) are a cornerstone in the treatment of lymphoid malignancies such as multiple myeloma (MM) and acute lymphoblastic leukemia (ALL). Yet, prolonged GC use is hampered by deleterious GC-related side effects and the emergence of GC r
Autor:
Frank Stenner, Leentje De Ceuninck, Frank Peelman, Dieter Defever, Sam Lievens, Jan Tavernier, Delphine Masschaele, Joris Wauman
Publikováno v:
PLoS ONE
PLOS ONE
PLoS ONE, Vol 12, Iss 5, p e0178132 (2017)
PLOS ONE
PLoS ONE, Vol 12, Iss 5, p e0178132 (2017)
RNF41 (Ring Finger Protein 41) is an E3 ubiquitin ligase involved in the intracellular sorting and function of a diverse set of substrates. Next to BRUCE and Parkin, RNF41 can directly ubiquitinate ErbB3, IL-3, EPO and RARα receptors or downstream s
Autor:
Travis McMurphy, Run Xiao, Andrew Slater, Lei Cao, Jan Tavernier, Daniel Magee, Lennart Zabeau
Publikováno v:
PLOS ONE
PLoS ONE, Vol 9, Iss 2, p e89895 (2014)
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e89895 (2014)
PLoS ONE
Environmental and genetic activation of a brain-adipocyte axis inhibits cancer progression. Leptin is the primary peripheral mediator of this anticancer effect in a mouse model of melanoma. In this study we assessed the effect of a leptin receptor an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d69c15f0684a795f149850a7dbf8b62
https://hdl.handle.net/1854/LU-4326617
https://hdl.handle.net/1854/LU-4326617
Autor:
Geertrui Denecker, Ali A. Bahar, Wim Declercq, Michael Devos, Sam Lievens, Marc Bracke, Dorien Clarisse, Valerie Gossye, Wim Vanden Berghe, Guy Haegeman, Nadia Bougarne, Sofie Desmet, Kris Gevaert, Jan Tavernier, Bart Ruttens, Zuzanna Drebert, Ruben Hoya-Arias, Ilse M. Beck, Karolien De Bosscher
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e69115 (2013)
PLOS ONE
PLoS ONE, Vol 8, Iss 7, p e69115 (2013)
PLOS ONE
Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-kappa B-mediated gene expression. However, the monomeric Compound A-activated GR is unable to trigger
Autor:
Yves Guisez, J. Van der Heyden, Geert Plaetinck, Annick Verhee, Jan Tavernier, Christian Oefner, T Tuypens, R Devos
Publikováno v:
Proceedings of the National Academy of Sciences. 92:5194-5198
A detailed structure-function analysis of human interleukin 5 (hIL5) has been performed. The hIL5 receptor is composed of two different polypeptide chains, the alpha and beta subunits. The alpha subunit alone is sufficient for ligand binding, but ass
Autor:
Jan Tavernier, Delphine Lavens, Irma Lemmens, Frank Peelman, Dominiek Catteeuw, Celia Bovijn, Isabel Uyttendaele
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44143 (2012)
PLoS ONE
PLoS ONE
The mammalian two-hybrid system MAPPIT allows the detection of protein-protein interactions in intact human cells. We developed a random mutagenesis screening strategy based on MAPPIT to detect mutations that disrupt the interaction of one protein wi
Autor:
Kris Gevaert, Annick Verhee, Els Pattyn, Frank Peelman, Isabel Uyttendaele, Julie Piessevaux, Evy Timmerman, Jan Tavernier, Joël Vandekerckhove
Publikováno v:
PLoS ONE
PLOS ONE
PLoS ONE, Vol 3, Iss 6, p e2427 (2008)
PLOS ONE
PLoS ONE, Vol 3, Iss 6, p e2427 (2008)
BACKGROUND: ISG15 is an Ubiquitin-like protein, highly induced by Type I Interferons. Upon the cooperative activity of specific Ubiquitinating enzymes, ISG15 can be conjugated to its substrates. Increasing evidence points to a role for protein ISGyla
Autor:
William A. Petri, Caitlin Naylor, Lennart Zabeau, Jan Tavernier, Hans P. Verkerke, Chelsea Marie
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94843 (2014)
PLOS ONE
PLoS ONE
PLOS ONE
PLoS ONE
Studies in human populations and mouse models of disease have linked the common leptin receptor Q223R mutation to obesity, multiple forms of cancer, adverse drug reactions, and susceptibility to enteric and respiratory infections. Contradictory resul
Autor:
Marleen Van Troys, Jan Tavernier, Karlien Van Wesemael, Krzysztof Kolmus, Sarah Gerlo, Guy Haegeman, Christophe Ampe
Publikováno v:
PLOS ONE
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e90649 (2014)
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e90649 (2014)
The proinflammatory cytokine Tumour Necrosis Factor (TNF)-alpha is implicated in a variety of skeletal muscle pathologies. Here, we have investigated how in vitro cotreatment of skeletal muscle C2C12 cells with b-agonists modulates the TNF-alpha-indu
By use of a 3' extension PCR strategy, cDNA clones were isolated spanning the transmembrane region and a complete cytoplasmic domain of the human interleukin 5 receptor alpha subunit (hIL5R alpha). These cDNAs differ from previously isolated clones e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8d8d8e7c8418d1e57247cc7ca1f6d5
https://europepmc.org/articles/PMC49641/
https://europepmc.org/articles/PMC49641/