Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jan Tavernier"'
Autor:
José Van der Heyden, Karolien De Bosscher, Joris Wauman, Raffaele Mori, Laura Icardi, Jan Tavernier, Frank Peelman, Lode De Cauwer
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
STAT3 is a pleiotropic transcription factor involved in homeostatic and host defense processes in the human body. It is activated by numerous cytokines and growth factors and generates a series of cellular effects. Of the STAT-mediated signal transdu
Autor:
Serge Van Calenbergh, Annick Verhee, Leentje De Ceuninck, Kevin Titeca, Kris Gevaert, Eva Cloots, Jan Tavernier, Sam Lievens, Delphine De Sutter, Emmy Van Quickelberghe, Sven Eyckerman, Evy Timmerman, Noortje Samyn
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
NATURE COMMUNICATIONS
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Cell lysis is an inevitable step in classical mass spectrometry–based strategies to analyse protein complexes. Complementary lysis conditions, in situ cross-linking strategies and proximal labelling techniques are currently used to reduce lysis eff
Autor:
Xiaofeng Xin, Julie M. Sahalie, Haiyuan Yu, Christophe Simon, David E. Hill, Nicolas Simonis, Amélie Dricot, Marc Vidal, Michael Snyder, Juyong Park, Michael E. Cusick, Irma Lemmens, Jean François Rual, Pascal Braun, Frederick P. Roth, Changyu Fan, Stanley Tam, Troy Moore, Leah Tardivo, Nenad Svrzikapa, Albert-László Barabási, Ryan R. Murray, Tong Hao, Adriana Motyl, Tomoko Hirozane-Kishikawa, Anne-Sophie De Smet, Alexei Vazquez, Kavitha Venkatesan, Muhammed A. Yildirim, Michael E. Hudson, Jan Tavernier, Nan Li, Charles Boone, Fana Gebreab
Publikováno v:
Science, 322 (5898
Current yeast interactome network maps contain several hundred molecular complexes with limited and somewhat controversial representation of direct binary interactions. We carried out a comparative quality assessment of current yeast interactome data
Autor:
Tim Vervliet, Vincenzo Sorrentino, Hristina Ivanova, Nael Nadif Kasri, Geert Bultynck, Giovanni Monaco, Jan B. Parys, Humbert De Smedt, Elke Decrock, Irma Lemmens, Elien Vandermarliere, Jan Tavernier, Luc Leybaert, Ludwig Missiaen, Lennart Martens
Publikováno v:
Scientific Reports, 5
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Anti-apoptotic B-cell lymphoma 2 (Bcl-2) family members target several intracellular Ca2+-transport systems. Bcl-2, via its N-terminal Bcl-2 homology (BH) 4 domain, inhibits both inositol 1,4,5-trisphosphate receptors (IP3Rs) and ryanodine receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1d47068ee499032b868eb07aa47298
https://hdl.handle.net/2066/153911
https://hdl.handle.net/2066/153911
Autor:
Yann Bordat, Franciane Paul, Stephan Wilmes, Florence Apparailly, Jan Tavernier, Guillaume Cartron, Gilles Uzé, Markus Staufenbiel, Stefaan De Koker, José Van der Heyden, Geneviève Garcin, Jacob Piehler
Publikováno v:
Nature Communications; Vol 5
Nature Communications
Nature Communications, Nature Publishing Group, 2014, 5 (1), ⟨10.1038/ncomms4016⟩
Nature Communications, 2014, 5 (1), ⟨10.1038/ncomms4016⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2014, 5 (1), ⟨10.1038/ncomms4016⟩
Nature Communications, 2014, 5 (1), ⟨10.1038/ncomms4016⟩
International audience; Systemic toxicity currently prevents exploiting the huge potential of many cytokines for medical applications. Here we present a novel strategy to engineer immunocytokines with very high targeting efficacies. The method lies i
Autor:
Geertrui Denecker, Ali A. Bahar, Wim Declercq, Michael Devos, Sam Lievens, Marc Bracke, Dorien Clarisse, Valerie Gossye, Wim Vanden Berghe, Guy Haegeman, Nadia Bougarne, Sofie Desmet, Kris Gevaert, Jan Tavernier, Bart Ruttens, Zuzanna Drebert, Ruben Hoya-Arias, Ilse M. Beck, Karolien De Bosscher
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e69115 (2013)
PLOS ONE
PLoS ONE, Vol 8, Iss 7, p e69115 (2013)
PLOS ONE
Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-kappa B-mediated gene expression. However, the monomeric Compound A-activated GR is unable to trigger
Autor:
Jan Tavernier, Delphine Lavens, Irma Lemmens, Frank Peelman, Dominiek Catteeuw, Celia Bovijn, Isabel Uyttendaele
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44143 (2012)
PLoS ONE
PLoS ONE
The mammalian two-hybrid system MAPPIT allows the detection of protein-protein interactions in intact human cells. We developed a random mutagenesis screening strategy based on MAPPIT to detect mutations that disrupt the interaction of one protein wi
Autor:
William A. Petri, Caitlin Naylor, Lennart Zabeau, Jan Tavernier, Hans P. Verkerke, Chelsea Marie
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94843 (2014)
PLOS ONE
PLoS ONE
PLOS ONE
PLoS ONE
Studies in human populations and mouse models of disease have linked the common leptin receptor Q223R mutation to obesity, multiple forms of cancer, adverse drug reactions, and susceptibility to enteric and respiratory infections. Contradictory resul