Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Thamilarasan Manivasagam"'
Autor:
Arokiasamy Justin Thenmozhi, Sathiya Sekar, Thamilarasan Manivasagam, Rajamani Barathidasan, Saravana Babu Chidambaram, Sugumar Mani, Gilles J. Guillemin, Musthafa Mohamed Essa, Meena Kishore Sakharkar, Murugan Sevanan
Publikováno v:
Neurotoxicity Research. 33:656-670
The present study was designed to ascertain the role of naringenin (NGN), a citrus fruit flavanone, against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced α-synuclein (SYN) pathology and neuroinflammation in a mouse model. NGN was admin
Autor:
Chinnasamy Dhanalakshmi, Thamilarasan Manivasagam, Musthafa Mohamed Essa, Udaiyappan Janakiraman, Gilles J. Guillemin, Arokiasamy Justin Thenmozhi, Byoung Joon Song
Publikováno v:
Physiology & Behavior. 173:132-143
Depression is frequently encountered during Parkinson's disease (PD) as a non-motor feature, which has been reported to cause and exaggerate motor deficits and neurodegenerative events in experimental PD models. We studied the effect of chronic mild
Autor:
Arokiasamy Justin Thenmozhi, Musthafa Mohamed Essa, Jagatheesan Nataraj, Thamilarasan Manivasagam
Publikováno v:
Neurochemical Research. 42:1354-1365
Regulation of various signalling (Ras-MAPK, PI3K and AKT) pathways by augmented activity of neurotrophic factors (NTFs) could prevent or halt the progress of dopaminergic loss in Parkinson's disease (PD). Various in vitro and in vivo experimental stu
Autor:
Thamilarasan Manivasagam, Musthafa Mohammed Essa, Jagatheesan Nataraj, Mushtaq A. Memon, M. Kavitha
Publikováno v:
Chemico-Biological Interactions. 331:109214
Autor:
Abid Bhat, Barathidasan Rajamani, Arokiasamy Justin Thenmozhi, Musthafa Mohamed Essa, Gilles J. Guillemin, Thamilarasan Manivasagam, Bipul Ray, Sugumar Mani, Sathiya Sekar, Saravana Babu Chidambaram
Publikováno v:
Neurotoxicity research. 34(3)
Many studies reported the neuroprotective effects of angiotensin II type 1 receptor (AT1R) antagonists in Parkinson’s disease (PD). However, the role of AT1R blockade on astroglial, in turn, dopaminergic functions in chronic PD is still to be studi
Publikováno v:
Neuroscience Letters. 599:12-19
Parkinson's disease (PD) is the second most common neurodegenerative disorder that mainly affects the movement of the aged populations. Lycopene is a carotenoid with unique pharmacological properties and its efficacy on experimental Hunginton's disea
Autor:
Govindasamy Pushpavathi Selvakumar, Thamilarasan Manivasagam, Musthafa Mohamed Essa, Udaiyappan Janakiraman, Arokiasamy Justin Thenmozhi
Publikováno v:
Brain Research. 1585:23-36
Parkinson's disease (PD) is a progressive neurodegenerative disorder that results mainly due to the death of dopaminergic neurons in the substantia nigra (SN), and subsequently has an effect on one's motor function and coordination. The current inves
Autor:
Thamilarasan Manivasagam, Namasivayam Elangovan, Chinnasamy Dhanalakshmi, Musthafa Mohamed Essa, Richard L. Jayaraj
Publikováno v:
Chemico-Biological Interactions. 220:149-157
Parkinson's disease (PD) is characterized by the progressive degeneration via apoptosis of nigrostriatal dopaminergic neurons associated with inflammation, resulting in behavioral anomalies. Therefore, an anti-apoptotic and anti-inflammatory regimen
Autor:
Richard L. Jayaraj, Namasivayam Elangovan, Thamilarasan Manivasagam, Karamkolly R. Rekha, Govindasamy Pushpavathi Selvakumar
Publikováno v:
Journal of Molecular Neuroscience. 55:184-197
Parkinson's disease (PD) is a common, chronic, and debilitating neurodegenerative disorder characterized by progressive loss of nigrostriatal dopaminergic neurons due to unknown factors. In the present study, we have evaluated if escin, a triterpene
Autor:
Muralikrishnan Dhanasekaran, Amit Naskar, Kochupurackal P. Mohanakumar, Thamilarasan Manivasagam, Raghavendra Singh, Joy Chakraborty, Bobby Thomas
Publikováno v:
Journal of Pineal Research. 55:304-312
The dopamine precursor, L-3,4-dihydroxyphenylalanine (L-DOPA), is the preferred drug for Parkinson’s disease, but long-term treatment results in the drug-induced dyskinesias and other side effects. This study was undertaken to examine whether melat