Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Reinaldo N. Takahashi"'
Autor:
Rodrigo A. Cunha, Reinaldo N. Takahashi, Joana I. Real, Filipe C. Matheus, Daniel Rial, Rui Daniel Prediger, Cristina Lemos, Leandro J. Bertoglio
Publikováno v:
Molecular Neurobiology. 53:3891-3899
The dorsolateral striatum (DLS) processes motor and non-motor functions and undergoes extensive dopaminergic degeneration in Parkinson's disease (PD). The nigrostriatal dopaminergic degeneration also affects other brain areas including the pre-fronta
Autor:
Patrícia A. Dombrowski, Claudio Da Cunha, Roger Walz, Rodrigo A. Cunha, Diana I Rodrigues, Paula Agostinho, Eduardo Luiz Gasnhar Moreira, Daniel Rial, Karin M. Moreira, Débora Cristina Hipólide, Reinaldo N. Takahashi, Fabrício A. Pamplona, Rui Daniel Prediger
Publikováno v:
European Journal of Neuroscience. 40:2479-2486
Cellular prion protein (PrP(C) ) is widely expressed in the brain. Although the precise role of PrP(C) remains uncertain, it has been proposed to be a pivotal modulator of neuroplasticity events by regulating the glutamatergic and serotonergic system
Publikováno v:
Neuroscience letters. 622
Understanding the mechanisms responsible for nonmotor manifestations of Parkinson's disease (PD) is crucial in the search for new therapeutic approaches. The aim of the present study was to evaluate the time course of behavioral, neurochemical, and m
Autor:
Frederico C. Pereira, Claudio Da Cunha, Rui Daniel Prediger, Cristina Lemos, Rodrigo A. Cunha, Roger Walz, Gisele de Oliveira Guaita, Ana C. Sequeira, Daniel Rial, Reinaldo N. Takahashi, Filipe C. Matheus, Joana I. Real, Leandro J. Bertoglio, Juliana Ben, Inês R. Pita
Publikováno v:
Behavioural brain research. 301
Parkinson's disease (PD) is characterized by motor dysfunction associated with dopaminergic degeneration in the dorsolateral striatum (DLS). However, motor symptoms in PD are often preceded by short-term memory deficits, which have been argued to inv
Autor:
Rui Daniel Prediger, Pablo Pandolfo, Filipe S. Duarte, Reinaldo N. Takahashi, Fabrício A. Pamplona
Publikováno v:
Behavioural Brain Research. 212:96-102
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the decline in cognitive functions, but it is also related to emotional disturbances. Since pain experience results from a complex integration of sensory, cognitive and affecti
Autor:
P. Mormède, Leandro F. Vendruscolo, E. Terenina, J. C. M. Vendruscolo, André Ramos, Reinaldo N. Takahashi
Publikováno v:
Genes, Brain and Behavior
Genes, Brain and Behavior, Wiley, 2009, 8 (3), pp.267-274. ⟨10.1111/j.1601-183X.2008.00465.x⟩
Genes, Brain and Behavior, Wiley, 2009, 8 (3), pp.267-274. ⟨10.1111/j.1601-183X.2008.00465.x⟩
Chantier qualité GA; International audience; This study investigated genetic influences on behavioral and neuroendocrine responses to cocaine sensitization. We used male and female rats of the inbred strains Lewis (LEW) and spontaneously hypertensiv
Autor:
Jorge Camilo Flório, Rui Daniel Prediger, Reinaldo N. Takahashi, Pablo Pandolfo, Luciano C. Batista, Rodrigo Medeiros
Publikováno v:
Experimental Neurology. 202:391-403
Many studies have shown that deficits in olfactory and cognitive functions precede the classical motor symptoms seen in Parkinson's disease (PD) and that olfactory testing may contribute to the early diagnosis of this disorder. Although the primary c
Autor:
Elena Terenina-Rigaldie, Frantz Raba, Reinaldo N. Takahashi, Pierre Mormède, André Ramos, Leandro F. Vendruscolo
Publikováno v:
Genes, Brain and Behavior
Genes, Brain and Behavior, Wiley, 2006, 5 (6), pp.441-450. ⟨10.1111/j.1601-183X.2005.00177.x⟩
Genes, Brain and Behavior, Wiley, 2006, 5 (6), pp.441-450. ⟨10.1111/j.1601-183X.2005.00177.x⟩
Previous studies using the inbred rat strains Lewis (LEW) and spontaneously hypertensive rats (SHR) led to the mapping of two quantitative trait loci, named Ofil1 (on chromosome 4 of the rat) and Ofil2 (on chromosome 7), for open-field inner locomoti
Publikováno v:
Behavioural Pharmacology. 16:209-218
Increasing evidence suggests that antagonistic interactions between specific subtypes of adenosine and dopamine receptors in the basal ganglia are involved in the control of motor activity. However, there are few studies investigating this interactio
Publikováno v:
Neuroscience Letters. 380:270-275
Δ9-THC and synthetic cannabinoids produce memory impairment in humans as well as in laboratory animals. The high concentration of cannabinoid CB1 receptors and the presence of endocannabinoids in the hippocampus suggest that a cannabinoid neurochemi