Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Qingzhen Yu"'
Autor:
Wenyu Lin, Qingzhen Yu, Tuo Shao, Mikhail Papisov, Andre J Jeyarajan, Jiahui Chen, Jian Rong, Zhen Chen, Lee Josephson, Steven H. Liang, Steve Rwema, Vasily Belov, Xiaoyun Deng, Raymond T. Chung, Hualong Fu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 308-315 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Monoacylglycerol lipase (MAGL) is a pivotal enzyme in the endocannabinoid system, which metabolizes 2-arachidonoylglycerol (2-AG) into the proinflammatory eicosanoid precursor arachidonic acid (AA). MAGL and other endogenous cannabinoid (EC) degradin
Autor:
Yiding Zhang, Jiahui Chen, Atsuto Hiraishi, Steven H. Liang, Tomoteru Yamasaki, Ming-Rong Zhang, Benjamin F. Cravatt, Wakana Mori, Lee Josephson, Richard Van, Jian Rong, Tuo Shao, Masayuki Fujinaga, Michael A. Schafroth, Akiko Hatori, Thomas Lee Collier, Jiyun Sun, Qingzhen Yu, Kuan Hu, Zhen Chen, Yihan Shao, Daisuke Ogasawara
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1686-1695 (2021)
As a serine hydrolase, monoacylglycerol lipase (MAGL) is principally responsible for the metabolism of 2-arachidonoylglycerol (2-AG) in the central nervous system (CNS), leading to the formation of arachidonic acid (AA). Dysfunction of MAGL has been