Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Wei-Yi Ong"'
Publikováno v:
NeuroMolecular Medicine. 25:1-13
Research advances have shed new insight into cellular pathways contributing to PD pathogenesis and offer increasingly compelling therapeutic targets. In this review, we made a broad survey of the published literature that report possible disease-modi
Publikováno v:
NeuroMolecular Medicine. 24:363-373
Autor:
Wei-Yi, Ong, Mei-Han, Kao, Wai-Mui, Cheung, Damien Meng-Kiat, Leow, Irwin Kee-Mun, Cheah, Teng-Nan, Lin
Publikováno v:
NeuroMolecular Medicine.
Ergothioneine (ET) is a naturally occurring antioxidant and cytoprotective agent that is synthesized by fungi and certain bacteria. Recent studies have shown a beneficial effect of ET on neurological functions, including cognition and animal models o
Autor:
Wei-Yi Ong, Deron R. Herr, Christopher P Chen, Mitchell K.P. Lai, Brenda Wan Shing Lam, Leona Ting Yuke Ho, Wee Siong Chew, Xin Ying Chua, Ping Xiang
Publikováno v:
NeuroMolecular Medicine. 23:47-67
Sphingosine 1-phosphates (S1Ps) are bioactive lipids that mediate a diverse range of effects through the activation of cognate receptors, S1P1-S1P5. Scrutiny of S1P-regulated pathways over the past three decades has identified important and occasiona
Autor:
Wei-Yi Ong, Samantha Chia Yi Ooi, Sally Shuxian Koh, Cao Qiong, Leona Ting Yuke Ho, Irwin K. Cheah, Barry Halliwell, Natalie Man Yin Lui, Deron R. Herr
Publikováno v:
NeuroMolecular Medicine
Neuromolecular Medicine
Neuromolecular Medicine
Ergothioneine (ET) is a naturally occurring antioxidant that is synthesized by non-yeast fungi and certain bacteria. ET is not synthesized by animals, including humans, but is avidly taken up from the diet, especially from mushrooms. In the current s
Autor:
Wai-Mui Cheung, Mei-Han Kao, Jin Jer Chen, Teng-Nan Lin, Deron R. Herr, Grace Y. Sun, Jui Sheng Wu, Wei-Yi Ong
Publikováno v:
NeuroMolecular Medicine. 23:199-210
Neuroinflammation has been shown to exacerbate ischemic brain injury, and is considered as a prime target for the development of stroke therapies. Clinacanthus nutans Lindau (C. nutans) is widely used in traditional medicine for treating insect bites
Autor:
Wan Shun Daniel Tan, Wei-Yi Ong, Sally Shuxian Koh, Wai Shiu Fred Wong, Deron R. Herr, Ting Yu Amelia Yam, Kanokporn Chayaburakul
Publikováno v:
Neuromolecular Medicine
Microglial cells are resident macrophages of the central nervous system (CNS) that respond to bioactive lipids such as docosahexaenoic acid (DHA). Low micromolar concentrations of DHA typically promote anti-inflammatory functions of microglia, but hi
Publikováno v:
Molecules. 27:3607
Recent studies on the ethnomedicinal use of Clinacanthus nutans suggest promising anti-inflammatory, anti-tumorigenic, and antiviral properties for this plant. Extraction of the leaves with polar and nonpolar solvents has yielded many C-glycosyl flav
Autor:
Malavika Srikanth, Kalashobini Chandrasaharan, Deron R. Herr, Wei-Yi Ong, Xinyuan Zhao, Kanokporn Chayaburakul
Publikováno v:
NeuroMolecular Medicine. 20:504-514
DHA is one of the most abundant fatty acids in the brain, largely present in stores of membrane phospholipids. It is readily released by the action of phospholipase A2 and is known to induce anti-inflammatory and neurotrophic effects. It is not thoug
Autor:
Maria V. Babak, Giampiero Spalluto, Wei-Yi Ong, Aaron Tan, Siew Lee Cheong, Giorgia Pastorin, Clarissa Lim, Yu Zong Chen, Karl-Norbert Klotz, Deron R. Herr, Jason S. E. Loo, Stephanie Federico, Gopalakrishnan Venkatesan
Publikováno v:
Molecules
Molecules, Vol 24, Iss 20, p 3661 (2019)
Molecules, Vol 24, Iss 20, p 3661 (2019)
Human A3 adenosine receptor hA3AR has been implicated in gastrointestinal cancer, where its cellular expression has been found increased, thus suggesting its potential as a molecular target for novel anticancer compounds. Observation made in our prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f14bceec5f55b21302d334a3c747c2
http://hdl.handle.net/11368/2954606
http://hdl.handle.net/11368/2954606