Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Cristina Dehelean"'
Autor:
Roxana Ghiulai, Marius Mioc, Roxana Racoviceanu, Alexandra Prodea, Andreea Milan, Dorina Coricovac, Cristina Dehelean, Ștefana Avram, Alina D. Zamfir, Cristian V. A. Munteanu, Viviana Ivan, Codruța Şoica
Publikováno v:
Molecules; Volume 27; Issue 21; Pages: 7359
Betulinic acid (BA) has been extensively studied in recent years mainly for its antiproliferative and antitumor effect in various types of cancers. Limited data are available regarding the pharmacokinetic profile of BA, particularly its metabolic tra
Autor:
Roxana Ghiulai, Alexandra Mioc, Roxana Racoviceanu, Marius Mioc, Andreea Milan, Alexandra Prodea, Alexandra Semenescu, Cristina Dehelean, Lucian Barbu Tudoran, Ștefana Avram, Cristina Trandafirescu, Codruța Șoica
Publikováno v:
Pharmaceuticals; Volume 15; Issue 11; Pages: 1362
Implementing metallic nanoparticles as research instruments for the transport of therapeutically active compounds remains a fundamentally vital work direction that can still potentially generate novelties in the field of drug formulation development.
Autor:
Ioana Zinuca Pavel, Diana Antal, Cristina Dehelean, Stefana Avram, Codruta Soica, Florina Ardelean, Corina Danciu
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 20:1817-1830
Background: The small chemical class of flavonolignans encompasses unique hybrid molecules with versatile biological activities. Their anticancer effects have received considerable attention, and a large body of supporting evidence has accumulated. M
Autor:
Gabriela Nistor, Marius Mioc, Alexandra Mioc, Mihaela Balan-Porcarasu, Roxana Racoviceanu, Alexandra Prodea, Andreea Milan, Roxana Ghiulai, Alexandra Semenescu, Cristina Dehelean, Codruța Șoica
Publikováno v:
Molecules; Volume 27; Issue 22; Pages: 7807
Cancer, in all its types and manifestations, remains one of the most frequent causes of death worldwide; an important number of anticancer drugs have been developed from plants, fungi and animals, starting with natural compounds that were later deriv
Autor:
Zorin Crainiceanu, Daniela Flondor, Iasmina Marcovici, George-Andrei Drăghici, Alexandra Enache, Georgeta Coneac, Ioana Macașoi, Cristina Dehelean, Claudia-Geanina Watz, Elena-Alina Moacă, Lavinia Vlaia, Florin Borcan, Ioana Olariu, Ramona Daniela Pârvănescu
Publikováno v:
Molecules
Volume 26
Issue 14
Molecules, Vol 26, Iss 4174, p 4174 (2021)
Volume 26
Issue 14
Molecules, Vol 26, Iss 4174, p 4174 (2021)
The skin integrity is essential due to its pivotal role as a biological barrier against external noxious factors. Pentacyclic triterpenes stand as valuable plant-derived natural compounds in the treatment of skin injuries due to their anti-inflammato
Autor:
Amadeus Dobrescu, Sebastian Simu, Iasmina Marcovici, Dorina Coricovac, Daniel Malita, Flavius Olaru, Cristina Dehelean, Dan Navolan, George Andrei Draghici
Publikováno v:
Molecules
Volume 26
Issue 9
Molecules, Vol 26, Iss 2776, p 2776 (2021)
Volume 26
Issue 9
Molecules, Vol 26, Iss 2776, p 2776 (2021)
Oral contraceptives (OCs) are widely used due to their efficiency in preventing unplanned pregnancies and treating several human illnesses. Despite their medical value, the toxicity of OCs remains a public concern. Previous studies indicate the carci
Autor:
Octavian Cretu, Dorina Coricovac, Iasmina Marcovici, Iulia Pinzaru, Codruta Soica, Stela Iurciuc, Marius Mioc, Cristina Dehelean
Publikováno v:
Molecules
Molecules, Vol 26, Iss 1109, p 1109 (2021)
Molecules, Vol 26, Iss 1109, p 1109 (2021)
Despite the recent advances in the field of chemically synthetized pharmaceutical agents, nature remains the main supplier of bioactive molecules. The research of natural products is a valuable approach for the discovery and development of novel biol
Autor:
Daliana Minda, Corina Danciu, Brigitta Kis, Ioana Zinuca Pavel, Alexandra Ghiƫu, Valentina Buda, Cristina Dehelean, Stefana Avram, Roxana Folescu
Publikováno v:
Analytical Cellular Pathology (Amsterdam)
Analytical Cellular Pathology, Vol 2021 (2021)
Analytical Cellular Pathology, Vol 2021 (2021)
One of the most important class of natural compounds with successful preclinical results in the management of cancer is the flavonoids. Due to the plethora of biological activities, apigenin (4 ′ ,5,7 trihydroxyflavone) is a main representant of th
Autor:
Vlad Tiberiu Alexa, Atena Galuscan, A. Cozma, Florin Borcan, Diana Obistioiu, Camelia Szuhanek, Cristina Dehelean, Daniela Jumanca
Publikováno v:
Molecules
Molecules, Vol 25, Iss 5502, p 5502 (2020)
Volume 25
Issue 23
Molecules, Vol 25, Iss 5502, p 5502 (2020)
Volume 25
Issue 23
Since ancient times complementary therapies have been based on the use of medicinal plants, natural preparations and essential oils in the treatment of various diseases. Their use in medical practice is recommended in view of their low toxicity, phar
Tetracyclic and Pentacyclic Triterpenes with High Therapeutic Efficiency in Wound Healing Approaches
Autor:
Ioana Macasoi, Alexandra Mioc, Octavian Marius Creţu, Diana Antal, Roxana Ghiulai, Marius Mioc, Mirela Voicu, Oana Janina Roşca, Cristina Dehelean, Tudor Olariu, Roxana Racoviceanu, Codruţa Şoica
Publikováno v:
Molecules
Molecules, Vol 25, Iss 5557, p 5557 (2020)
Molecules, Vol 25, Iss 5557, p 5557 (2020)
Wounds are among the most common skin conditions, displaying a large etiological diversity and being characterized by different degrees of severity. Wound healing is a complex process that involves multiple steps such as inflammation, proliferation a