Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Yoshiyuki Takahashi"'
Autor:
Yusuke Okuno, Shinsuke Kataoka, Asahito Hama, Nozomu Kawashima, Kyoko Yamashita, Daiei Kojima, Eri Nishikawa, Kenji Kasai, Rieko Taniguchi, Masato Nakaguro, Atsushi Narita, Motoharu Hamada, Atsuko Nakazawa, Daisuke Ichikawa, Hajime Okita, Kyogo Suzuki, Seiji Mizuno, Seiji Kojima, Norihiro Murakami, Nobuhiro Nishio, Hideki Muramatsu, Yoshiyuki Takahashi, Yoshie Shimoyama
Publikováno v:
NPJ Genomic Medicine
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Pediatric solid tumors are a heterogeneous group of neoplasms with over 100 subtypes. Clinical and histopathological diagnosis remains challenging due to the overlapping morphological and immunohistochemical findings and the presence of atypical case
Autor:
Yoshiyuki Takahashi, Nobuhiro Nishio, Hideki Muramatsu, Rieko Taniguchi, Yuichi Ishikawa, Makoto Murata, Nozomu Kawashima, Eri Nishikawa, Ryo Hanajiri, Motoharu Hamada, Atsushi Narita
Publikováno v:
Blood. 138:3831-3831
Introduction: Chimeric antigen receptor-modified T cells targeting CD19 (CD19.CAR-T cells) have shown clinical success in patients with hematological malignancies. Despite the encouraging results obtained with this novel therapy, a major concern to i
Autor:
Ayako Hattori, Yoshiyuki Takahashi, Kazuhito Satou, Seiji Kojima, Yusuke Okuno, Ikumi Hori, Yuji Nakamura, Daisuke Ieda, Shinji Saitoh, Yutaka Negishi, Hideki Muramatsu, Kei Ohashi, Tomoko Kawai
Publikováno v:
Human Genome Variation
Human Genome Variation, Vol 6, Iss 1, Pp 1-4 (2019)
Human Genome Variation, Vol 6, Iss 1, Pp 1-4 (2019)
Patients with variants in CUL4B exhibit syndromic intellectual disability (MIM #300354). A seven-year-old boy presented with intellectual disability, a history of seizure, characteristic facial features, and short stature. Whole-exome sequencing dete
Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells
Autor:
Daisuke Morita, Miyuki Tanaka, Yozo Nakazawa, Nobuhiro Nishio, Matthew H. Wilson, Kazuyuki Matsuda, Satoshi Suzuki, Yoshiyuki Takahashi, Shoji Saito, Nozomu Kawashima, Yasuhiro Maeda, Gianpietro Dotti, Yusuke Okuno, Cliona M. Rooney
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 8, Iss C, Pp 131-140 (2018)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Adoptive T cell therapy using chimeric antigen receptor (CAR)-modified T cells is a promising cancer immunotherapy. We previously developed a non-viral method of gene transfer into T cells using a piggyBac transposon system to improve the cost-effect
Autor:
Eiko Nagamoto, Yuichi Kageshita, Hironobu Ihn, Takeshi Inoue, Yoshiyuki Takahashi, Kenichi Tanaka, Yusuke Okuno, Chiaki Murase, Michihiro Kono, Takuya Takeichi, Eri Shimizu, Masashi Akiyama, Junko Ishikawa, Satoshi Fukushima, Akane Kawamoto
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2413-2420 (2018)
Neu-Laxova syndrome (NLS) is a very rare autosomal recessive congenital disorder characterized by disturbed development of the central nervous system and the skin and caused by mutations in any of the three genes involved in de novo l-serine biosynth
Autor:
Yuji Nakamura, Naomi Tsuchida, Yoshiyuki Takahashi, Shinji Saitoh, Kohji Kato, Naomichi Matsumoto
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0221482 (2019)
PLoS ONE, Vol 14, Iss 8, p e0221482 (2019)
There have been increasing number of reports of SZT2-related neurological diseases, the main symptoms of which are epilepsy, developmental delay, macrocephaly and a dysmorphic corpus callosum. SZT2 functions as a regulator of mechanistic target of ra
Autor:
Masaya Takemoto, Tohru Daikoku, Hiroki Hosoi, Kazuhide Saito, Takamitsu Aihara, Masahiro Ikeda, Kimiyasu Shiraki, Tetsuya Nishida, Yoshiyuki Takahashi
Publikováno v:
Microbiology and Immunology. 57:396-399
Drug-resistant cytomegalovirus appears during prolonged anti-cytomegalovirus therapy. Assays for human cytomegalovirus viral protein kinase (UL97) and viral DNA polymerase (UL54) gene mutations conferring drug resistance have been used rather than su
Autor:
Noriko Nagai, Yoshiyuki Takahashi, Shinji Kunishima, Seiji Kojima, Daiei Kojima, Hideki Muramatsu, Okuno Yusuke
Publikováno v:
Annals of Hematology. 96:1065-1066
Publikováno v:
African Journal of Biotechnology; Vol 10, No 46 (2011); 9522-9527
Sperm suspensions of 4 male mice (A, B, C and D), having an initial motility grade of 3.5 were used to examine the presence of DNA topoisomerase II (top 2) activity in sperm heads. The initial percentage motile of male A was 75%, male B was 80%, male
Autor:
Michael I. Lerman, Elena Cherkasova, Xin Tian, Ramaprasad Srinivasan, Julie Hong, David S. Schrump, W. M. Linehan, V. N. Senchenko, Elizabeth B Malinzak, Sheila Rao, Michael L. Nickerson, Maria J. Merino, Richard W. Childs, Anna V. Kudryavtseva, Yoshiyuki Takahashi
Publikováno v:
Oncogene
A human endogenous retrovirus type E (HERV-E) was recently found to be selectively expressed in most renal cell carcinomas (RCCs). Importantly, antigens derived from this provirus are immunogenic, stimulating cytotoxic T cells that kill RCC cells in