Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Yong J. Lee"'
Autor:
Kalishwaralal Kalimuthu, Chenicheri K. Keerthana, Manikandan Mohan, Jaison Arivalagan, Johnson Retnaraj Samuel Selvan Christyraj, Michael A. Firer, Mohammad Haroon Asif Choudry, Ruby John Anto, Yong J. Lee
Publikováno v:
J Cell Biochem
Selenium is incorporated into the body via the selenocysteine biosynthesis pathway, which is critical in the synthesis of selenoproteins such as glutathione peroxidases and thioredoxin reductases. Selenoproteins, which play a key role in several biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf9fd8fbcf1fd7c7a0d17649480dfd3
https://europepmc.org/articles/PMC8940641/
https://europepmc.org/articles/PMC8940641/
Autor:
Xinxin Song, Haroon A. Choudry, Yong J. Lee, Yong Tae Kwon, Young Sun Lee, David L. Bartlett, Ashok K. Dilly, Dae Hee Lee
Publikováno v:
Molecular Cancer Research. 16:1077-1091
Emerging evidence demonstrates that autophagy and apoptosis are interconnected and their interplay greatly affects cell death. However, the key regulators in this crosstalk remain elusive. Therefore, the role of N-terminal arginylated BiP (R-BiP)/Bec
Autor:
Yong J. Lee, Chuanyue Wu, Se Hoon Hong, David L. Bartlett, Seog Young Kim, Yong Tae Kwon, Per H. Basse
Publikováno v:
Journal of Cellular Biochemistry. 117:2289-2301
Cancer stem cells (CSCs) are capable of initiation and metastasis of tumors. Therefore, understanding the biology of CSCs and the interaction between CSCs and their counterpart non-stem cells is crucial for developing a novel cancer therapy. We used
Autor:
Yong J. Lee, Ki Sa Sung, William T. Kwon, Zong Sheng Guo, Dae Hee Lee, David L. Bartlett, Yong Tae Kwon, Sang Cheul Oh
Publikováno v:
Journal of Cellular Biochemistry. 117:1078-1091
It is well known that tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis can be initially triggered by surface death receptors (the extrinsic pathway) and subsequently amplified through mitochondrial dysfunction (the in
Autor:
Ashok K. Dilly, Yong J. Lee, Yong Tae Kwon, David L. Bartlett, Haroon A. Choudry, Xinxin Song
Publikováno v:
Molecular Cancer Research. 13:1533-1543
Colorectal peritoneal carcinomatosis (CPC) exhibits severe tumor hypoxia, leading to drug resistance and disease aggressiveness. This study demonstrates that the combination of the chemotherapeutic agent mitomycin C with the proteasome inhibitor bort
Autor:
Yong Tae Kwon, Dae Hee Lee, David L. Bartlett, Yoshiro Saito, Xinxin Song, Daeho Kim, Bo Yeon Kim, Sang Mi Shim, Jung Lim Kim, Sung Tae Kim, Sang Cheul Oh, Zong Sheng Guo, Ah Jung Heo, Soyeon Jeong, Yong J. Lee, Junho Lee
Publikováno v:
Autophagy. 14(11)
Macroautophagy is induced under various stresses to remove cytotoxic materials, including misfolded proteins and their aggregates. These protein cargoes are collected by specific autophagic receptors such as SQSTM1/p62 (sequestosome 1) and delivered
Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5
Autor:
Dae Hee Lee, Jian Yu, David L. Bartlett, Yong Seok Park, Haroon A. Choudry, Yong J. Lee, Seong Hye Park, So Yeon Jeong, Young Sun Lee, Sang Cheul Oh
Publikováno v:
Journal of cellular biochemistry. 120(1)
Ferroptosis is considered genetically and biochemically distinct from other forms of cell death. In this study, we examined whether ferroptosis shares cell death pathways with other types of cell death. When human colon cancer HCT116, CX-1, and LS174
Publikováno v:
Molecular cancer research : MCR. 16(7)
Since its discovery in 2012, ferroptosis has been well characterized by the accumulation of lipid peroxides due to the failure of glutathione-dependent antioxidant defenses. It is known as an iron-dependent form of programmed cell death, which is dis
Autor:
Joonsung Hwang, Sang Cheul Oh, Shin Hyuk Kang, Ki Sa Sung, Dae Hee Lee, Su Ran Mun, Hyungsin Kim, Young Dong Yoo, Changhoon Ji, Seong Hye Park, Kyung Jae Park, Deric M. Park, Yong J. Lee, Seung-Ki Kim, Kim Bo Yeon, Seung Ah Choi, Aaron Ciechanover, Yong Tae Kwon, Hyunjoo Cha-Molstad
Although proteasome inhibitors (PIs) are used as anticancer drugs to treat various cancers, their relative therapeutic efficacy on stem cells vs. bulk cancers remains unknown. Here, we show that stem cells derived from gliomas, GSCs, are up to 1,000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034fb9c71b3cc892afa2853f84d3f13c
https://europepmc.org/articles/PMC5210095/
https://europepmc.org/articles/PMC5210095/
Publikováno v:
Molecular Cancer Research. 10:1567-1579
Colorectal cancer is the third leading cause of cancer-related mortality in the world. The main cause of death because of colorectal cancer is hepatic metastases, which can be treated using isolated hepatic perfusion (IHP), allowing treatment of colo