Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Yasuo Urata"'
Autor:
Jeong Heo, Ja-Der Liang, Chang Won Kim, Hyun Young Woo, I-Lun Shih, Tung-Hung Su, Zhong-Zhe Lin, So Young Yoo, Stanley Chang, Yasuo Urata, Pei-Jer Chen
Publikováno v:
Molecular Therapy.
Autor:
Nobuhiko Kanaya, Tomoko Tsumura, Ryoma Sugimoto, Toshiyoshi Fujiwara, Satoru Kikuchi, Masashi Hashimoto, Yasuo Urata, Hiroshi Tazawa, Kento Kumon, Masahiko Nishizaki, Shinji Kuroda, Yuki Hamada, Yoshihiko Kakiuchi, Chiaki Yagi, Shunsuke Kagawa
Publikováno v:
Mol Ther
Extracellular vesicles (EVs) play important roles in various intercellular communication processes. The abscopal effect is an interesting phenomenon in cancer treatment, in which immune activation is generally considered a main factor. We previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694e1e8c95f8e15ca5b3ea376ea13ad5
https://europepmc.org/articles/PMC8530926/
https://europepmc.org/articles/PMC8530926/
Autor:
Yasuo Urata, Satoru Kikuchi, Masashi Hashimoto, Nobuhiko Kanaya, Hiroyuki Mizuguchi, Kento Kumon, Shunsuke Kagawa, Tomoko Tsumura, Katsuyuki Aoyama, Tetsushi Kubota, Yoshihiko Kakiuchi, Masahiko Nishizaki, Shinji Kuroda, Toshiyoshi Fujiwara, Hiroshi Tazawa, Toshiaki Morihiro
Publikováno v:
Mol Ther
The clinical benefit of monotherapy involving immune checkpoint inhibitors (ICIs) such as anti-programmed death-1 antibody (PD-1 Ab) is limited to small populations. We previously developed a telomerase-specific oncolytic adenovirus, Telomelysin (OBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7e840e5e7e2a07a49da0c071434c45
https://europepmc.org/articles/PMC7054725/
https://europepmc.org/articles/PMC7054725/
Autor:
Hiroshi Tazawa, Yasuo Urata, Toshiyoshi Fujiwara, Robert M. Hoffman, Shunsuke Kagawa, Hiroyuki Kishimoto, Shuya Yano, Kiyoto Takehara
Publikováno v:
Journal of Cellular Biochemistry. 118:3635-3642
We have established an orthotopic nude-mouse model of gastric cancer carcinomatosis peritonitis, a recalcitrant disease in human patients. Human MKN45 poorly-differentiated human gastric cancer cells developed carcinomatosis peritonitis upon orthotop
Autor:
Shuya Yano, Toshiyoshi Fujiwara, Yasuo Urata, Hiroshi Tazawa, Michael Bouvet, Robert M. Hoffman, Shunsuke Kagawa, Kiyoto Takehara, Hiroyuki Kishimoto
Publikováno v:
Cancer Gene Therapy. 24:45-47
We previously described the development of a highly-invasive, triple-negative breast cancer (TNBC) variant using serial orthotopic implantation of MDA-MB-231 human breast cancer in nude mice. The isolated variant is highly invasive in the mammary gla
Autor:
Toshiyoshi Fujiwara, Hiroshi Tazawa, Michael Bouvet, Shinji Miwa, Hiroyuki Kishimoto, Yasuo Urata, Robert M. Hoffman, Shuya Yano, Mako Yamamoto, Shunsuke Kagawa, Yukihiko Hiroshima, Makoto Toneri
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy, vol 23, iss 7
Fluorescence-guided surgery (FGS) of cancer is an area of intense current interest. However, although benefits have been demonstrated with FGS, curative strategies need to be developed. Glioblastoma multiforme (GBM) is one of the most invasive of can
Autor:
Masahiko Nishizaki, Shinji Kuroda, Takeshi Nagasaka, Yuuri Hashimoto, Yasuo Urata, Yasuhiro Shirakawa, Satoru Kikuchi, Hiroshi Tazawa, Robert M. Hoffman, Shunsuke Kagawa, Hiroyuki Kishimoto, Toshiyoshi Fujiwara
Publikováno v:
Molecular Therapy. 23(3):501-509
Currently, early gastrointestinal cancers are treated endoscopically, as long as there are no lymph node metastases. However, once a gastrointestinal cancer invades the submucosal layer, the lymph node metastatic rate rises to higher than 10%. Theref
Autor:
Hiroshi Tazawa, Toshiyoshi Fujiwara, Shuya Yano, Robert M. Hoffman, Shunsuke Kagawa, Kiyoto Takehara, Hiroyuki Kishimoto, Yasuo Urata
We previously demonstrated that quiescent cancer cells in a tumor are resistant to conventional chemotherapy as visualized with a fluorescence ubiquitination cell cycle indicator (FUCCI). We also showed that proliferating cancer cells exist in a tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8fb816bf6f107964a674b68f7d268e
https://europepmc.org/articles/PMC5351920/
https://europepmc.org/articles/PMC5351920/
Autor:
Nobuyoshi Katagiri, Shinsaku Togo, Kyoko Tomita, Yasuo Urata, Hiroyuki Mizuguchi, Nobuhiro Narii, Toshiyoshi Fujiwara, Fuminori Sakurai, Masashi Tachibana, Kazuhisa Takahashi, Mitsuhiro Machitani, Masaaki Ouchi
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Circulating tumor cells (CTCs) are promising biomarkers in several cancers, and thus methods and apparatuses for their detection and quantification in the blood have been actively pursued. A novel CTC detection system using a green fluorescence prote
Autor:
Shuhei Osaki, Futoshi Uno, Ryosuke Yoshida, Aki Yoshida, Toshiyoshi Fujiwara, Hiroshi Tazawa, Yuuri Hashimoto, Shuya Yano, Tsuyoshi Sasaki, Joe Hasei, Toshifumi Ozaki, Yasuo Urata, Toshiyuki Kunisada, Shunsuke Kagawa
Publikováno v:
Gene Therapy. 20:112-118
Adenovirus serotype 5 (Ad5) is frequently used as an effective vector for induction of therapeutic transgenes in cancer gene therapy or of tumor cell lysis in oncolytic virotherapy. Ad5 can infect target cells through binding with the coxsackie and a