Zobrazeno 1 - 10
of 1 600
pro vyhledávání: '"Wheeler, A"'
Autor:
Tamara Mirzapoiazova, Liz Tseng, Bolot Mambetsariev, Haiqing Li, Chih-Hong Lou, Alex Pozhitkov, Sravani Keerthi Ramisetty, Sangkil Nam, Isa Mambetsariev, Brian Armstrong, Jyoti Malhotra, Leonidas Arvanitis, Mohd Wasim Nasser, Surinder K. Batra, Steven T. Rosen, Deric L. Wheeler, Sharad S. Singhal, Prakash Kulkarni, Ravi Salgia
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110132- (2024)
Summary: Although up to 80% small cell lung cancer (SCLC) patients’ response is good for first-line chemotherapy regimen, most patients develop recurrence of the disease within weeks to months. Here, we report cytostatic effect of leflunomide (Lefl
Externí odkaz:
https://doaj.org/article/c1d2afcf8682490aa1a6bb5963b1e1f1
Autor:
Linlin Guo, Atish Mohanty, Sharad Singhal, Saumya Srivastava, Arin Nam, Charles Warden, Sravani Ramisetty, Yate-Ching Yuan, Hyejin Cho, Xiwei Wu, Aimin Li, Manik Vohra, Srinivas Vinod Saladi, Deric Wheeler, Leonidas Arvanitis, Erminia Massarelli, Prakash Kulkarni, Yiming Zeng, Ravi Salgia
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107302- (2023)
Summary: This study investigates the role of integrin β4 (ITGB4) and stemness-associated factor SOX2 in platinum resistance in lung squamous cell carcinoma (LUSC). The expression of SOX2 and ITGB4 is found to be high in all LUSC subtypes, but the im
Externí odkaz:
https://doaj.org/article/9962e7214592483093812b263a3e559e
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101134- (2022)
Summary: This protocol details the induction of inflammation and acute myelin degeneration in larval zebrafish with a duration of
Externí odkaz:
https://doaj.org/article/efe8febc3f9641dcb9555b3d8da9af9c
Autor:
Hair, Molly, Yanase, Ryuji, Moreira-Leite, Flávia, Wheeler, Richard John, Sádlová, Jovana, Volf, Petr, Vaughan, Sue, Sunter, Jack Daniel
Publikováno v:
PLoS Pathogens; 2/28/2024, Vol. 20 Issue 2, p1-28, 28p
Autor:
Saumya Srivastava, Ka Ming Pang, Mari Iida, Michael S. Nelson, Jiayi Liu, Arin Nam, Jiale Wang, Isa Mambetsariev, Raju Pillai, Atish Mohanty, Nellie McDaniel, Amita Behal, Prakash Kulkarni, Deric L. Wheeler, Ravi Salgia
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101692- (2020)
Summary: The tyrosine kinase receptor ephrin receptor A2 (EPHA2) is overexpressed in lung (LSCC) and head and neck (HNSCC) squamous cell carcinomas. Although EPHA2 can inhibit tumorigenesis in a ligand-dependent fashion via phosphorylation of Y588 an
Externí odkaz:
https://doaj.org/article/862bc629bc1841d3ab9053896facbb15
Autor:
Alexander Yuile, Laveniya Satgunaseelan, Joe Wei, Marina Kastelan, Michael F. Back, Maggie Lee, Heng Wei, Michael E. Buckland, Adrian Lee, Helen R. Wheeler
Publikováno v:
Current Issues in Molecular Biology. 44:5117-5125
Both IDH1 (isocitrate dehydrogenase 1) and IDH2 (isocitrate dehydrogenase 2) mutations play a vital role in the development of gliomas through disruption of normal cellular metabolic processes. Here we describe a case of a patient with an IDH-mutant
Autor:
Ryan Cordner, Michelle Jhun, Akanksha Panwar, HongQiang Wang, Nicole Gull, Ramachandran Murali, Joseph H. McAbee, Armen Mardiros, Akane Sanchez-Takei, Mia W. Mazer, Xuemo Fan, Emmanuel Jouanneau, John S. Yu, Keith L. Black, Christopher J. Wheeler
Publikováno v:
Oncogene.
The promise of adaptive cancer immunotherapy in treating highly malignant tumors such as glioblastoma multiforme (GBM) can only be realized through expanding its benefits to more patients. Alleviating various modes of immune suppression has so far fa
Publikováno v:
Molecular Genetics and Genomics.
Publikováno v:
Bioinformatics. 39
Motivation Researchers usually conduct statistical analyses based on models built on raw data collected from individual participants (individual-level data). There is a growing interest in enhancing inference efficiency by incorporating aggregated su
Autor:
Marcus Mendes, Jarjapu Mahita, Nina Blazeska, Jason Greenbaum, Brendan Ha, Kelly Wheeler, Jiyao Wang, Deborah Shackelford, Alessandro Sette, Bjoern Peters
Publikováno v:
Protein Science. 32