Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tarja Lamminen"'
Autor:
Wojciech Senkowski, Laura Gall-Mas, Matías Marín Falco, Yilin Li, Kari Lavikka, Mette C. Kriegbaum, Jaana Oikkonen, Daria Bulanova, Elin J. Pietras, Karolin Voßgröne, Yan-Jun Chen, Erdogan Pekcan Erkan, Jun Dai, Anastasia Lundgren, Mia Kristine Grønning Høg, Ida Marie Larsen, Tarja Lamminen, Katja Kaipio, Jutta Huvila, Anni Virtanen, Lars Engelholm, Pernille Christiansen, Eric Santoni-Rugiu, Kaisa Huhtinen, Olli Carpén, Johanna Hynninen, Sampsa Hautaniemi, Anna Vähärautio, Krister Wennerberg
Publikováno v:
Developmental Cell.
Autor:
Olli Carpén, Katja Kaipio, Kaisa Huhtinen, Antti Häkkinen, Erdogan Pekcan Erkan, Noora Andersson, Naziha Mansuri, Sampsa Hautaniemi, Anna Vähärautio, Johanna Hynninen, Tarja Lamminen, Amjad Alkodsi, Rainer Lehtonen, Kaiyang Zhang, Jun Dai, Sakari Hietanen
Publikováno v:
Bioinformatics
Motivation A major challenge in analyzing cancer patient transcriptomes is that the tumors are inherently heterogeneous and evolving. We analyzed 214 bulk RNA samples of a longitudinal, prospective ovarian cancer cohort and found that the sample comp
Autor:
Michelle Welsh, Sari Mäkelä, Tomi Streng, Taija Saloniemi, Philippa T. K. Saunders, Tarja Lamminen, Matti Poutanen
Publikováno v:
Molecular and Cellular Endocrinology. 301:163-168
When present in excess amounts during fetal life, androgens can impair female development by inducing masculinization. On way to modify fetal steroid concentration is by altering the expression of hydroxysteroid (17beta) dehydrogenases (HSD17Bs). Hum
Autor:
Philippa T. K. Saunders, Tarja Lamminen, Kaisa Huhtinen, Harry Kujari, Michelle Welsh, Taija Saloniemi, Matti Poutanen
Publikováno v:
Molecular Endocrinology. 21:2627-2636
Hydroxysteroid (17beta) dehydrogenases (HSD17Bs) belong to the short-chain dehydrogenase/reductase family consisting of a diverse pool of enzymes with oxidoreductase activity. HSD17B enzymes catalyze the conversion between 17-keto and 17-hydroxy ster
Publikováno v:
MHR: Basic science of reproductive medicine. 11:601-605
FSH is a pituitary gonadotropin that along with LH plays a key role in the regulation of gonadal function. The gonadotropic hormones are composed of two subunits, the common alpha subunit and the hormone-specific beta subunit, which determines the bi
Autor:
Ilpo Huhtaniemi, Jukka Hellman, Pirjo Pakarinen, Pulak R. Manna, Rene J. Herrera, Tarja Lamminen, Min Jiang
Publikováno v:
Molecular Human Reproduction. 8:201-212
Upon screening for polymorphisms in the human luteinizing hormone beta-subunit (LH beta) gene, we discovered a novel mutation in the LH beta signal peptide with functional consequences for signal transduction in mouse Leydig tumour cells (mLTC-1). Th
Autor:
Eeva Nikoskelainen, Vesa Juvonen, Pertti Aula, Marja-Liisa Savontaus, Tarja Lamminen, Maila Penttinen
Publikováno v:
Human Mutation. 9:412-417
Leber hereditary optic neuropathy (LHON) is a maternally inherited eye disease most commonly caused by mitochondrial DNA (mtDNA) point mutation at position 11778, 3460, or 14484. Approximately 14% of families show heteroplasmy for the pathogenic muta
Autor:
Matti Poutanen, Hubert Thole, Taija Saloniemi, Kaisa Huhtinen, Bettina Husen, Pasi Koskimies, Tarja Lamminen, Josef Messinger
Publikováno v:
Molecular and cellular endocrinology. 301(1-2)
Summary Hydroxysteroid (17β) dehydrogenase 1 (HSD17B1) catalyzes the reaction between the low active 17-ketosteroids and the highly active 17beta-hydroxysteroids. In the present study, we have generated transgenic (TG) mice expressing human (h) HSD1
Autor:
Pertti Aula, Vesa Juvonen, Mårten Wikström, Eeva Nikoskelainen, Anna Majander, Marja-Liisa Savontaus, Tarja Lamminen
Publikováno v:
FEBS letters. 412(2)
A lowered efficiency of oxidative phosphorylation was recently found in a Leber hereditary optic neuropathy (LHON) proband carrying a mutation in the mtDNA gene for subunit 6 of the membrane-bound F0 segment of the F1F0-ATP synthase [9]. This phenoty