Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Taina Turpeenniemi-Hujanen"'
Autor:
Maria Honkavuori-Toivola, Taina Turpeenniemi-Hujanen, Ylermi Soini, Markku Santala, Anne Talvensaari-Mattila
Publikováno v:
Disease Markers, Vol 35, Iss 4, Pp 261-266 (2013)
Disease markers
Disease markers
Objective. The aim of this study was to evaluate the combined effects of MMP-2 and TIMP-2 protein immunoreactivities on the prognosis in endometrial carcinoma.Methods. Paraffin-embedded tissue samples from 225 primary endometrioid adenocarcinomas and
Publikováno v:
Clinical and Experimental Metastasis. 15:318-328
Overproduction of matrix metalloproteinases (MMPs) and alterations in adhesive and migratory behavior are common characteristics of metastatic cancer cells. Ovarian cancer is a highly invasive type of malignancy. The effect of the antineoplastic drug
Publikováno v:
Fertility and Sterility. 64:132-138
Objective To study the role of extracellular matrix (ECM) proteins in supporting the development and implantation competence of human embryos. Design Expression of an implantation site adhesive glycoprotein, oncofetal fibronectin, and basement membra
Autor:
Ylermi Soini, Kaisu Järvinen, Mika Rämet, Taina Turpeenniemi-Hujanen, Katariina Castrén, Katja Pekkala, Kirsi Vähäkangas, Paavo Pääkkö
Publikováno v:
Carcinogenesis. 16:2117-2124
p53 inhibits cell cycle progression and DNA damaging cytostatics induce p53 protein expression, indicating that p53 responds to DNA damage. We have measured benzo[a]pyrene (BP)-induced DNA damage in association with p53 expression. The most relevant
Publikováno v:
International Journal of Cancer. 47:576-581
We have studied the effects of interferons (IFNs) on the attachment, collagenase IV activity, chemotactic migration and in vitro invasion of human melanoma (A2058) cells treated for various time periods with human recombinant interferon alpha (hrIFN-
Autor:
Erkki Hujanen, Unnur Thorgeirsson, Taina Turpeenniemi-Hujanen, Matti Höyhtyä, Lance A. Liotta, Karl Tryggvason
Publikováno v:
International Journal of Cancer. 46:282-286
Monoclonal antibodies (MAbs) against human type-IV collagenase were developed and used for studies on enzyme activity and tumor-cell invasion in vitro. Fifteen MAb clones were generated against the enzyme purified form serum-free culture medium of hu
Publikováno v:
Fertility and sterility. 58(1)
Objective To explore the possible similarities between the biochemical processes of embryo implantation and malignant invasion. Design The expression of a basement membrane (BM) glycoprotein laminin, a matrix binding cell surface receptor protein β1
Concomitant hydroxylation of proline and lysine residues in collagen using purified enzymes in vitro
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 800:59-65
Concomitant hydroxylation of proline and lysine residues in protocollagen was studied using purified enzymes. The data suggest that prolyl 4-hydroxylase (prolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase (4-hydroxylating), EC 1.14.11.2) an
Publikováno v:
Collagen and Related Research. 1:355-366
Lysyl hydroxylase was isolated as an essentially homogeneous protein from human fetal tissues and as a homogeneous protein from placental tissue by a procedure involving ammonium sulfate fractionation, affinity chromatography on concanavalin A-agaros
Publikováno v:
Journal of Biological Chemistry. 261:1883-1889
We have studied the effect of laminin on type IV collagenolytic activity elaborated by malignant cells in culture. Laminin (at concentrations of 4-8 micrograms/ml) added to serum-free culture supernatants of subconfluent A2058 human melanoma cells si