Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Simona Simone"'
Autor:
Simona Simone, Anna Gallone, Giovanni Stallone, Claudia Cinefra, Francesca Conserva, Chiara Divella, Michele Rossini, Paola Pontrelli, Viviana Casagrande, Giuseppe Castellano, Francesco Pesce, Francesco Giorgino, Massimo Federici, Mariagrazia Barozzino, Rossella Menghini, Loreto Gesualdo, Alessandra Stasi
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5194, p 5194 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5194, p 5194 (2021)
Diabetic nephropathy (DN) is the most frequent cause of end-stage renal disease. Tubulointerstitial accumulation of lysine 63 (K63)-ubiquitinated (Ub) proteins is involved in the progression of DN fibrosis and correlates with urinary miR-27b-3p downr
Autor:
Grazia Vocino, Giuseppe Grandaliano, Luigi Laviola, Paola Pontrelli, Annarita Oranger, Francesca Conserva, Giuseppe Castellano, Francesco Giorgino, Margherita Gigante, Mariagrazia Barozzino, Salvatore Di Paolo, Michele Rossini, Maria Teresa Rocchetti, Massimo Papale, Simona Simone, Loreto Gesualdo
Publikováno v:
The FASEB Journal. 31:308-319
The purpose of our study was to evaluate how hyperglycemia (HG) influences Lys63 protein ubiquitination and its involvement in tubular damage and fibrosis in diabetic nephropathy (DN). Gene and protein expression of UBE2v1, a ubiquitin-conjugating E2
Autor:
Rossana Franzin, Vincenzo Cantaluppi, Chiara Divella, Giuseppe Castellano, Giuseppe Stefano Netti, Loreto Gesualdo, Enrico Fiaccadori, Antonio Crovace, Giovanni Pertosa, Alessandra Spinelli, Simona Simone, Alessandra Stasi, Luca Lacitignola, Francesco Staffieri, Giuseppe Grandaliano, Fabio Sallustio
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 15, p 3682 (2019)
Volume 20
Issue 15
International Journal of Molecular Sciences, Vol 20, Iss 15, p 3682 (2019)
Volume 20
Issue 15
During sepsis, the increased synthesis of circulating lipopolysaccharide (LPS)-binding protein (LBP) activates LPS/TLR4 signaling in renal resident cells, leading to acute kidney injury (AKI). Pericytes are the major source of myofibroblasts during c
Publikováno v:
Diabetes
OBJECTIVE—To investigate potential mechanisms of oxidative DNA damage in a rat model of type 1 diabetes and in murine proximal tubular epithelial cells and primary culture of rat proximal tubular epithelial cells. RESEARCH DESIGN AND METHODS—Phos
Autor:
Giuseppe Grandaliano, Giovanni Pertosa, Simona Simone, Daniela Marrone, Francesco Paolo Schena, Michela Soccio, Loreto Gesualdo
Publikováno v:
Journal of the American Society of Nephrology. 16:2477-2486
Priming of the coagulation cascade during hemodialysis (HD) leads to the release of activated factor X (FXa). The binding of FXa to its specific receptors, effector protease receptor-1 (EPR-1) and protease-activated receptor-2 (PAR-2), may induce the
Autor:
Mario Colucci, Stefania C Pietanza, Giovanni Pertosa, Francesca Incampo, Giuseppe Grandaliano, Loreto Gesualdo, Simona Simone, Margherita Gigante, Marica Cariello, Antonia Loverre, Francesco Paolo Schena
Publikováno v:
Antioxidantsredox signaling. 16(5)
This study investigated on (i) the role of gp91(phox)/NOX2 in reactive oxygen species (ROS) generation in hemodialysis (HD) patients, and (ii) the link between clotting activation and ROS production in this setting.The study was performed on peripher
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 7, Iss 1, p 10 (2008)
Molecular Cancer, Vol 7, Iss 1, p 10 (2008)
Background Tuberous sclerosis complex (TSC) is caused by defects in one of two tumor suppressor genes, TSC-1 or TSC-2. TSC-2 gene encodes tuberin, a protein involved in the pathogenesis of kidney tumors. Loss of heterozygosity (LOH) at the TSC2 locus
Autor:
Simona Simone, Giovanni Pertosa, F. P. Schena, Giuseppe Castellano, Daniela Marrone, A. Di Vittorio, Giuseppe Dalfino, Carmen Capobianco, Giuseppe Grandaliano
Publikováno v:
Molecular Immunology. 44:3936-3937
Autor:
Giuseppe Castellano, Claudia Curci, M. Carielloa, E. van Amersfoort, Vincenzo Montinaro, F. P. Schena, Simona Simone, Loreto Gesualdo, Beatrijs Oortwijn, Giuseppe Grandaliano
Publikováno v:
Molecular Immunology. 48:1692