Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Simon Peter Williams"'
Autor:
Peter M. Haggie, Alexandra M. Fulton, Stanley W. Botchway, Rebecca Harmston, Randolf Jordan, Anthony W. Parker, Ignasi Barba, Kevin M. Brindle, Simon-Peter Williams
Publikováno v:
Biochemical Journal. 390:787-790
A novel method for the fluorescence detection of proteins in cells is described in the present study. Proteins are labelled by the selective biosynthetic incorporation of 5-hydroxytryptophan and the label is detected via selective two-photon excitati
Autor:
Annie Ogasawara, Jan Marik, Alexander N. Vanderbilt, Herman Gill, Judith E. Flores, Sharon Yee, Avi Ashkenazi, Jeff N. Tinianow, Simon-Peter Williams
Publikováno v:
Nuclear medicine and biology. 40(1)
An immunoPET imaging probe for the detection of phosphatidylserine was developed and tested in animal models of human cancer treated with pro-apoptotic therapy. We hypothesized that the relatively long plasma half-life of a probe based on a full-leng
Publikováno v:
Journal of Molecular Recognition. 6:159-165
Models of metabolic flux regulation are frequently based on an extrapolation of the kinetic properties of enzymes measured in vitro to the intact cell. Such an extrapolation assumes a detailed knowledge of the intracellular environment of these enzym
Publikováno v:
Biochemical Society Transactions. 19:997-1001
Publikováno v:
FEBS Letters. (1):121-124
Phosphoglycerate kinase was fluorine-labelled in the yeast Saccharomyces cerevisiae by inducing enzyme synthesis in the presence of 5-fluorotryptophan. 19F NMR measurements on the intact cells showed two resonances from the two tryptophan residues in