Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Seung-Jae Lee"'
Autor:
Seung-Jae Lee, Seokjun Ha
Publikováno v:
BMB Reports. 56:49-55
Autor:
Tae-Kyung Kim, Eun-Jin Bae, Byung Chul Jung, Minsun Choi, Soo Jean Shin, Sung Jun Park, Jeong Tae Kim, Min Kyo Jung, Ayse Ulusoy, Mi-Young Song, Jun Sung Lee, He-Jin Lee, Donato A. Di Monte, Seung-Jae Lee
Publikováno v:
Experimental & molecular medicine 54(12), 2148-2161 (2022). doi:10.1038/s12276-022-00895-w
The clinical progression of neurodegenerative diseases correlates with the spread of proteinopathy in the brain. The current understanding of the mechanism of proteinopathy spread is far from complete. Here, we propose that inflammation is fundamenta
Autor:
Hanseul Lee, Seung-Jae Lee
Publikováno v:
Molecules and Cells. 45:763-770
Autor:
Eun-Jin Bae, Minsun Choi, Jeong Tae Kim, Dong-Kyu Kim, Min Kyo Jung, Changyoun Kim, Tae-Kyung Kim, Jun Sung Lee, Byung Chul Jung, Soo Jean Shin, Ka Hyun Rhee, Seung-Jae Lee
Publikováno v:
Experimental & Molecular Medicine. 54:788-800
Cell-to-cell propagation of α-synuclein is thought to be the underlying mechanism of Parkinson’s disease progression. Recent evidence suggests that inflammation plays an important role in the propagation of protein aggregates. However, the mechani
Autor:
Jaehoon Bae, Kwanwoo Lee, Ji-Sun Park, Jinseok Jung, Hirofumi Tachibana, Yoshinori Fujimura, Motofumi Kumazoe, Jae Sung Lim, Young-Chang Cho, Seung-Jae Lee, Su-Jin Park
Publikováno v:
Current Issues in Molecular Biology; Volume 44; Issue 12; Pages: 6247-6256
Epigallocatechin 3-O-gallate (EGCG) is a predominant component in green tea with various health benefits. The 67 kDa laminin receptor (67LR) is a nonintegrin cell surface receptor that is overexpressed in various types of cancer; 67LR was identified
Publikováno v:
Molecules and Cells
Aging is associated with functional and structural declines in organisms over time. Organisms as diverse as the nematode Caenorhabditis elegans and mammals share signaling pathways that regulate aging and lifespan. In this review, we discuss recent c
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 4015
Meretrix lusoria (M. lusoria) is an economically important shellfish which is widely distributed in South Eastern Asia that contains bioactive peptides, proteins, and enzymes. In the present study, the extracted meat content of M. lusoria was enzymat
Publikováno v:
Molecular brain 15(1), 27 (2022). doi:10.1186/s13041-022-00913-y
Abnormal deposition of α-synuclein aggregates in Lewy bodies and Lewy neurites is the hallmark lesion in Parkinson’s disease (PD). These aggregates, thought to be the culprit of disease pathogenesis, spread throughout the brain as the disease prog
Autor:
Eliezer Masliah, Michael Mante, Anthony Adame, Brian Spencer, Seung-Jae Lee, Edward Rockenstein, Jerel A. Fields, Soo Jean Shin, Somin Kwon, Robert A. Rissman, Michiyo Iba, Changyoun Kim
Publikováno v:
Experimental & Molecular Medicine
Synucleinopathies are age-related neurological disorders characterized by the progressive deposition of α-synuclein (α-syn) aggregates and include Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Although cell-to-cell α-syn transmis
Publikováno v:
International Journal of Biological Sciences
YTH domain family 2 (YTHDF2) is an N6-methyladenosine (m6A) binding protein promoting mRNA degradation in various biological processes. Despite its essential roles, the role of YTHDF2 in determining cell fates has not been fully elucidated. Notch sig