Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ryo, Ito"'
Autor:
Mai Mochizuki, Sadafumi Kawamura, Kazuto Matsuura, Keiichi Tamai, Takayuki Imai, Wataru Iwai, Jun Yasuda, Akira Sugawara, Yukinori Asada, Makoto Abue, Tomoko Yamazaki, Haruna Fujimori, Rie Shibuya-Takahashi, Satoshi Saijoh, Ryo Ito, Yukio Katori, Mao Nakamura-Shima, Kazuo Sugamura, Kazunori Yamaguchi, Yu Katayose, Yuta Wakui, Kennichi Satoh
Publikováno v:
Biochemical and Biophysical Research Communications. 537:132-139
Cancer stem cells (CSCs) are believed to cause cancer metastasis and recurrence. BEX2 (brain expressed X-linked gene 2) is a CSC-related gene that is expressed in dormant CSCs in cholangiocarcinoma and induces resistance against chemotherapy. The aim
Publikováno v:
Biochemical and Biophysical Research Communications. 534:672-679
Aldosterone is synthesized in the adrenal by the aldosterone synthase CYP11B2. Although the control of CYP11B2 expression is important to maintain the mineral homeostasis, its overexpression induced by the depolarization-induced calcium (Ca2+) signal
Autor:
Ryo Ito, Hiroki Sakamoto, Koji Miyanishi, Kazuyuki Murase, Akira Sakurada, Masayoshi Kobune, Takahiro Osuga, Masanori Sato, Kohichi Takada, Junji Kato, Shingo Tanaka, Tomohiro Kubo, Kota Hamaguchi, Yusaku Nakabeppu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Non-alcoholic steatohepatitis (NASH)-related HCC is associated with oxidative stress. However, the mechanisms underlying the development of NASH-related HCC is unclear. MUTYH is one of the enzymes that is involved in repair of oxidative DNA damage. T
Publikováno v:
Diabetes. 69
Background: RFX6 was identified as a causative gene of Mitchell-Riley syndrome (MRS), an autosomal recessive disease associated with neonatal diabetes and morphological disorders in development of the endodermal lineage such as pancreatic hypoplasia
Publikováno v:
Biochemical and Biophysical Research Communications. 489:21-28
CYP11B2 is a key enzyme involved in the synthesis of the mineralocorticoid aldosterone. CYP11B2 expression in the adrenal glands is controlled by the renin-angiotensin system (RAS), and plays an important role in the maintenance of electrolyte metabo
Autor:
Ikuko Sato, Ryo Ito, Kengo Yazawa, Hiroki Shimada, Yuuki Imai, Atsushi Yokoyama, Akira Sugawara
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 134-140 (2016)
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 134-140 (2016)
DNA methylation is closely involved in the regulation of cellular differentiation, including chondrogenic differentiation of mesenchymal stem cells. Recent studies showed that Ten–eleven translocation (TET) family proteins converted 5-methylcytosin
Autor:
Kiyoshi Takagi, Jun Kanno, Atsushi Yokoyama, Akira Sugawara, Tetsuya Sato, Katsuhide Igarashi, Yasuyuki Ohkawa, Takashi Baba, Ryo Ito, Maky Otsuka, Yurina Shishido, Ken Ichirou Morohashi
Publikováno v:
Journal of Biological Chemistry. 289:18152-18162
Regulation of spatiotemporal gene expression in higher eukaryotic cells is critical for the precise and orderly development of undifferentiated progenitors into committed cell types of the adult. It is well known that dynamic epigenomic regulation (i
Publikováno v:
Journal of Biological Chemistry. 287:19792-19803
TATA-binding protein-like protein (TLP) is involved in development, checkpoint, and apoptosis through potentiation of gene expression. TLP-overexpressing human cells, especially p53-containing cells, exhibited a decreased growth rate and increased pr
Serofendic Acid Promotes Stellation Induced by cAMP and cGMP Analogs in Cultured Cortical Astrocytes
Autor:
Yuki Takada-Takatori, Akinori Akaike, Ryota Taguchi, Hachiro Sugimoto, Tetsuhiro Niidome, Yasuhiko Izumi, Hiroshi Katsuki, Toshiaki Kume, Ryo Ito
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 1, Pp 110-118 (2009)
We investigated the effect of serofendic acid, a neuroprotective substance derived from fetal calf serum, on the morphological changes in cultured cortical astrocytes. Cultured astrocytes developed a stellate morphology with several processes followi
Autor:
Atsushi Yokoyama, Masataka Kudo, Kaori Sugawara, Sadayoshi Ito, Masahiro Nezu, William E. Rainey, Yuko Iki, Akiko Saito-Hakoda, Fumitoshi Satoh, Ryo Ito, Kyoko Shimizu, Akira Sugawara, Ken Matsuda, Ikuko Sato, Naotaka Kogure, Hiroki Shimada, Takeo Yoshikawa, Akira Uruno, Takako Saito-Ito
Publikováno v:
Molecular and cellular endocrinology. 383(1-2)
We generated a stable H295R cell line expressing aldosterone synthase gene (CYP11B2) promoter/luciferase chimeric reporter construct that is highly sensitive to angiotensin II (AII) and potassium, and defined AII receptor blocker (ARB) effects. In th