Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Matthew A. Brown"'
Autor:
Nicolas Wieder, Juliana Coraor Fried, Choah Kim, Eriene-Heidi Sidhom, Matthew R. Brown, Jamie L. Marshall, Carlos Arevalo, Moran Dvela-Levitt, Maria Kost-Alimova, Jonas Sieber, Katlyn R. Gabriel, Julian Pacheco, Clary Clish, Hamdah Shafqat Abbasi, Shantanu Singh, Justine Rutter, Martine Therrien, Haejin Yoon, Zon Weng Lai, Aaron Baublis, Renuka Subramanian, Ranjan Devkota, Jonnell Small, Vedagopuram Sreekanth, Myeonghoon Han, Donghyun Lim, Anne E. Carpenter, Jason Flannick, Hilary Finucane, Marcia C. Haigis, Melina Claussnitzer, Eric Sheu, Beth Stevens, Bridget K. Wagner, Amit Choudhary, Jillian L. Shaw, Juan Lorenzo Pablo, Anna Greka
Publikováno v:
bioRxiv
SummaryCellular exposure to free fatty acids (FFA) is implicated in the pathogenesis of obesity-associated diseases. However, studies to date have assumed that a few select FFAs are representative of broad structural categories, and there are no scal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7daa44ca6aa3c52a2ff38c29c3f14b60
https://doi.org/10.1101/2023.02.19.529127
https://doi.org/10.1101/2023.02.19.529127
Autor:
Kwun M. Fong, Rayleen V. Bowman, Janet G. Shaw, Michael Gattas, Jessica Harris, Aideen M. McInerney-Leo, Shannon R. Joseph, Fiona Simpson, Po-Ling Inglis, Matthew A. Brown, Satomi Okano, Hui Yi Chew, Ian A. Yang, Lawrie Wheeler, Caroline Cooper, Tim Hassall, Mhairi Marshall, Emma L. Duncan, Paul Leo, Lisa K. Anderson
Publikováno v:
Human Molecular Genetics
Lung cancer is the commonest cause of cancer deaths worldwide. Although strongly associated with smoking, predisposition to lung cancer is also heritable, with multiple common risk variants identified. Rarely, dominantly inherited non-small-cell lung
Autor:
Areonna C. Schreiber, Adam J. Rossano, Carmen J. Reynolds, Heather L. Holmes, Matthew R. Brown, Aleksey Matveyenko, Michael F. Romero
Publikováno v:
The FASEB Journal. 36
Autor:
Tomonori Azuma, Tomáš Pánek, Alexander K. Tice, Motoki Kayama, Mayumi Kobayashi, Hideaki Miyashita, Toshinobu Suzaki, Akinori Yabuki, Matthew W. Brown, Ryoma Kamikawa
Publikováno v:
Molecular Biology and Evolution. 39
Ochrophyta is an algal group belonging to the Stramenopiles and comprises diverse lineages of algae which contribute significantly to the oceanic ecosystems as primary producers. However, early evolution of the plastid organelle in Ochrophyta is not
Autor:
Xidong Feng, Ye Che, Adam M. Gilbert, Reto Horst, Kris A. Borzilleri, Matthew Merrill Hayward, Carolyn A. Leverett, James Schiemer, Yilin Meng, Justin I. Montgomery, Matthew F. Calabrese, Mark C. Noe, Daniel P. Uccello, Stephen P. Brown, Matthew Frank Brown, Yingrong Xu
Publikováno v:
Nature Chemical Biology. 17:152-160
Heterobifunctional chimeric degraders are a class of ligands that recruit target proteins to E3 ubiquitin ligases to drive compound-dependent protein degradation. Advancing from initial chemical tools, protein degraders represent a mechanism of growi
Autor:
Jamie-Lee M. Thompson, Daniel W. D. West, Thomas M. Doering, Boris P. Budiono, Sarah J. Lessard, Lauren G. Koch, Steven L. Britton, Nuala M. Byrne, Matthew A. Brown, Kevin J. Ashton, Vernon G. Coffey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
PLoS ONE, Vol 17, Iss 1, p e0261723 (2022)
Skeletal muscle atrophy is a physiological response to disuse, aging, and disease. We compared changes in muscle mass and the transcriptome profile after short-term immobilization in a divergent model of high and low responders to endurance training
Autor:
Trishan Gajanand, Jeff S. Coombes, Camilla J. Williams, Larisa M. Haupt, Shelley E. Keating, Emily R. Cox, Monique E. Francois, David Bishop, Zhixiu Li, Rodney A. Lea, Emeline M. Van Craenenbroeck, Dorthe Stensvold, Paul Beckers, Joyce S. Ramos, Luciana Torquati, Sylvan L. J. E. Janssen, Brendon J. Gurd, Matthew A. Brown, Nicholas R Harvey, Jonathan P. Little, Xu Yan, Jenna L. Taylor, Erin J. Howden, Jacob T. Bonafiglia, Ioannis D. Papadimitriou, Robert G. Fassett, Ulrik Wisløff, Anja Bye, Ilaria Croci, Nir Eynon, Véronique Cornelissen, Kevin J. Ashton, Christopher M. Hearon, Macsue Jacques, Satyam Sarma, Lyn R. Griffiths
Publikováno v:
Journal of Biomedical Science
Journal of Biomedical Science, 28, 1
Journal of Biomedical Science, 28
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-15 (2021)
Journal of biomedical science
Journal of Biomedical Science, 28, 1
Journal of Biomedical Science, 28
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-15 (2021)
Journal of biomedical science
Background Low cardiorespiratory fitness (V̇O2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O2peak, there is considerable inter-individual va
Publikováno v:
New England Journal of Medicine. 380:2582-2587
Publikováno v:
Diabetes. 69
Metabolic stressors common to type 2 diabetes (T2D) lead to perturbations of β-cell’s transcriptional identity which provide β-cells an adaptive survival advantage at the expense of compromised function (i.e., dedifferentiation). Increase in the
Autor:
Matthew W, Brown, Alexander K, Tice
Publikováno v:
Nature Methods
Diverse microbial ecosystems underpin life in the sea. Among these microbes are many unicellular eukaryotes that span the diversity of the eukaryotic tree of life. However, genetic tractability has been limited to a few species, which do not represen