Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Marsha Wills-Karp"'
Autor:
Traci E. Stankiewicz, Cheryl L. Rewerts, Jazzminn Hembree, Christine Raver, Marsha Wills-Karp, Isaac T.W. Harley, Christopher L. Karp, Stephanie Walters, Matthias H. Tschöp, Paul T. Pfluger, Stacey L. Burgess, Jaclyn W. McAlees, Daniel A. Giles, Jordan Downey, R. Balfour Sartor, Leah M. Flick, Senad Divanovic
Publikováno v:
Mol. Metab. 2, 171-183 (2013)
Alterations in the gut microbiota have been proposed to modify the development and maintenance of obesity and its sequelae. Definition of underlying mechanisms has lagged, although the ability of commensal gut microbes to drive pathways involved in i
Autor:
Marsha Wills-Karp, Naina Gour
Aberrant production of the prototypical type 2 cytokines, interleukin (IL)-4 and IL-13 has long been associated with the pathogenesis of allergic disorders. Despite tremendous scientific inquiry, the similarities in their structure, and receptor usag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b882ece4a0f6f280bc41fce51a3b0f7
https://europepmc.org/articles/PMC4532591/
https://europepmc.org/articles/PMC4532591/
Autor:
Patricia C. Fulkerson, Nina E. King, Keith F. Stringer, Samuel M. Pope, Matthew P. Doepker, David P. Witte, Anil Mishra, Nikolaos M. Nikolaidis, Fred D. Finkelman, Eric B. Brandt, Marc E. Rothenberg, Marsha Wills-Karp, Nives Zimmermann
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 32:428-435
Asthma is a complex inflammatory pulmonary disorder that is on the rise despite intense ongoing research. We aimed to elucidate novel pathways involved in the pathogenesis of asthma. Employing asthma models induced by different allergens (ovalbumin a
Autor:
Susan Ewart, Marsha Wills-Karp
Publikováno v:
Nature Reviews Genetics. 5:376-387
The prevalence of complex genetic immune disorders, such as asthma, arthritis and diabetes, has escalated in recent decades. Despite the formidable challenges posed by the identification of susceptibility genes in complex genetic disorders such as th
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 27:413-418
Epidemiologic studies have suggested that exposure to airborne particulate matter (PM) can exacerbate allergic airway responses; however, the mechanism(s) are not well understood. We and others have recently shown that development of airway hyperresp
Autor:
Thomas E. Sussan, Sarah McCormick, Sanjay Juvekar, Lonny Yarmus, Patrick N. Breysse, Jung Hyun Kim, Shyam Biswal, Sundeep Salvi, Jonathan Fallica, Jason Akulian, Maureen R. Horton, Vijendra Ingole, Anurag Agrawal, Jesse Negherbon, David Feller-Kopman, Marsha Wills-Karp
Approximately 3 billion people-half the worldwide population-are exposed to extremely high concentrations of household air pollution due to the burning of biomass fuels on inefficient cookstoves, accounting for 4 million annual deaths globally. Yet,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac280a62c82122b439c6dcc5db5fa8aa
https://europepmc.org/articles/PMC4068935/
https://europepmc.org/articles/PMC4068935/
Autor:
Anne K. Vehmas, David R. Borchelt, Donald L. Price, Diane McCarthy, Marsha Wills-Karp, Marilyn J. Peper, Gay Rudow, Jackie Luyinbazi, Lawrence T. Siew, Juan C. Troncoso
Publikováno v:
DNA and Cell Biology. 20:713-721
Although the pathogenesis of Alzheimer's disease (AD) is not fully understood, growing evidence indicates that the deposition of beta-amyloid (Abeta) and the local reactions of various cell types to this protein play major roles in the development of
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 24:545-555
Because mouse strains susceptible to bleomycin, such as C57BL/ 6J, tend to produce T helper type 1 (Th1) cytokines in response to immune activation, we hypothesized that the inflammatory response to bleomycin is mediated, in part, by local production
Autor:
Douglas Kuperman, Susan Ewart, Gary Peltz, Clarke G. Tankersley, Andrew Grupe, Eric E. Schadt, Dennis M. Shubitowski, Marsha Wills-Karp
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 23:537-545
Identification of the genetic loci underlying asthma in humans has been hampered by variability in clinical phenotype, uncontrolled environmental influences, and genetic heterogeneity. To circumvent these complications, the genetic regulation of asth
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 12:396-403
Inhalation of elevated levels of ozone produces a potent inflammatory response in the lung. The magnitude of this response to ozone exposure in mice is inbred strain dependent with the susceptible phenotype being exemplified by the C57BL/6J (B6) stra