Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maria Speranza"'
Autor:
Maria Domenica Alvau, Manuel Zinellu, Giulia Maria Grazia Puggioni, Gaia Giovanna Maria Rocchitta, Gianfranco Bazzu, Maria Speranza Desole, Giammario Calia, Pier Andrea Serra, Rossana Migheli, Giulia Mercanti, Pietro Giusti
Publikováno v:
Brain Research. 1538:159-171
The neurotoxin MPTP is known to induce dopamine release and depletion of ATP in the striatum of rats. Therefore, we studied the changes induced by MPTP and pargyline protection both on striatal dopamine release and on extracellular energy metabolites
Autor:
Giammario Calia, Sonia Dedola, Giulia Maria Grazia Puggioni, Gaia Giovanna Maria Rocchitta, Pier Andrea Serra, Giovanni Esposito, Rossana Migheli, John P. Lowry, Gianfranco Bazzu, Egidio Miele, Robert D. O'Neill, Maria Speranza Desole
Publikováno v:
Analytical Biochemistry. 380:323-330
A novel dual channel in vitro apparatus, derived from a previously described design, has been coupled with dopamine (DA) microsensors for the flow-through detection of DA secreted from PC12 cells. The device, including two independent microdialysis c
Autor:
Maria Speranza Desole, L. Sciola, Maria Rosaria Delogu, Egidio Miele, Pier Andrea Serra, Rossana Migheli, Alessandra Spano, Gaia Giovanna Maria Rocchitta, Maddalena Miele, G Monaco
Publikováno v:
Journal of Biological Chemistry. 277:34451-34461
Swiss mice were given 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 25 mg/kg/day, for 5 consecutive days and killed at different days after MPTP discontinuance. Decreases in striatal tyrosine hydroxylase activity and levels of dopamine and its
Autor:
Rossana Migheli, Chiara Godani, L. Sciola, Danilo Zangani, Pier Andrea Serra, Egidio Miele, Maria Speranza Desole, Maria Rosaria Delogu, Guglielmo De Natale
Publikováno v:
Journal of Neurochemistry. 73:1155-1163
L-DOPA and manganese both induce oxidative stress-mediated apoptosis in catecholaminergic PC12 cells. In this study, exposure of PC12 cells to 0.2 m M MnCl 2 or 10-20 μ M L-DOPA neither affected cell viability, determined by the 3-(4,5-dimethylthiaz
Autor:
Maria Stella Anna Mura, Guglielmo De Natale, Giovanni Esposito, Paolo Enrico, Maddalena Miele, L. Fresu, Egidio Miele, Maria Speranza Desole, Rossana Migheli
Publikováno v:
Brain Research. 723:154-161
Since ascorbic acid (AA) reportedly suppresses tolerance to and dependence on morphine in humans and rodents, levels of dopamine (DA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), 3-methoxytyramine (3-MT), 5-hydroxytryptamine (5-HT),
Publikováno v:
Neuroscience Letters. 209:193-196
Oxidative stress is thought to play a key role both in the neurotoxin MPTP- and manganese (Mn)-induced neurotoxicity and in apoptotic cell death. In the present study, we report that Mn and the MPTP analogue 1-methyl-4-(2′-ethylphenyl)-1,2,3,6-tetr
Autor:
Rossana Migheli, Giovanni Esposito, Bianca Marchetti, Giuseppe Enrico Grella, Maddalena Miele, Gaia Giovanna Maria Rocchitta, Egidio Miele, Maria Paola Mura, Maria Speranza Desole, Pier Andrea Serra
Publikováno v:
Brain research. 1047(1)
We showed previously that exogenous iron potentiated nitric oxide (NO) donor-induced release of striatal dopamine (DA) in freely moving rats, using microdialysis. In this study, the increase in dialysate DA induced by intrastriatal infusion of the NO
Autor:
Giovanni Esposito, Maria Pina Mura, Rossana Migheli, Gaia Giovanna Maria Rocchitta, Maddalena Miele, Pier Andrea Serra, Egidio Miele, Maria Speranza Desole
Publikováno v:
Brain research. 1023(2)
We showed previously, using in vitro microdialysis, that the activation of the soluble guanylate cyclase (sGC)/cyclic GMP pathway was the underlying mechanism of the extracellular Ca(2+)-dependent effects of exogenous NO on dopamine (DA) secretion fr
Autor:
Elisabetta Cagetti, Mario Carta, Luisa Mancuso, Francesca Biggio, Enrico Sanna, Fabio Busonero, Maria Speranza Desole, Federico Massa, Paolo Follesa, Annalisa Manca, Elisabetta Maciocco, Giovanni Biggio
Publikováno v:
Brain research. Molecular brain research. 92(1-2)
The effects of long-term exposure to, and subsequent withdrawal of, diazepam or imidazenil (full and partial agonists of the benzodiazepine receptor, respectively) on the abundance of GABA(A) receptor subunit mRNAs and peptides were investigated in r
Autor:
Patricia A. Masso-Welch, Maria Speranza Desole, Kathleen M. Darcy, Elisabeth S. Bellamy, Danilo Zangani, Margot M. Ip
Publikováno v:
Differentiation; research in biological diversity. 64(2)
It has previously been shown that mammary stromal cells possess the ability to maintain a fibroblast-like phenotype or differentiate in vitro into mature adipocytes in a hormone-dependent manner. This paper reports that rat mammary stromal cells can