Zobrazeno 11 - 20
of 64
pro vyhledávání: '"Maria Sasvari-Szekely"'
Publikováno v:
Molecular Genetics and Metabolism. 74:484-488
Decreased activity of plasma cholinesterase is responsible for prolonged apnea during anesthesia using neuromuscular blockers such as suxamethonium and mivacurium. More than 20 mutations have been identified so far in the BCHE gene resulting in impai
Autor:
Zsolt Ronai, Maria Sasvari-Szekely, Erika Kovács, Anna Szekely, Zsofia Nemoda, András Guttman, Sarah Shandrick
Publikováno v:
ELECTROPHORESIS. 22:4008-4011
Large-scale genotyping of the repeat polymorphism in the regulatory region of the serotonin transporter gene (5-HTTLPR) was attempted by polymerase chain reaction (PCR) amplification followed by gel microchip electrophoresis analysis. The multilane (
Autor:
Zsolt Ronai, Maria Sasvari-Szekely, András Guttman, Judit Gervai, Maria Staub, Csaba Barta, Krisztina Lakatos
Publikováno v:
ELECTROPHORESIS. 22:1102-1105
The -521C/Tsingle nucleotide polymorphism (SNP) in the promoter region of the dopamine D4 receptor gene (DRD4) has recently been detected in oriental (Japanese) individuals and related to novelty seeking and schizophrenia. Here, we report the analysi
Publikováno v:
ELECTROPHORESIS. 22:779-782
Rapid molecular diagnosis of 21-hydroxylase deficiency by detecting the most common mutation in the 21-hydroxylase gene is presented using primer extension and capillary electrophoresis with a polyvinyl pyrrolidone matrix. DNA samples were subjected
Autor:
Iannis Talianidis, Zsolt Csapó, Tatjana Spasokoukotskaja, Maria Staub, Staffan Eriksson, Maria Sasvari-Szekely
Publikováno v:
Biochemical Pharmacology. 61:191-197
Deoxycytidine kinase (dCK, EC.2.7.1.74) is a key enzyme in the intracellular metabolism of 2-chlorodeoxyadenosine, 1-β- d -arabinofuranosylcytosine, difluorodeoxycytidine, and other drugs used in chemotherapy of different leukaemias and solid tumour
Publikováno v:
Journal of Chromatography A. 853:519-525
Ultrathin-layer agarose gel electrophoresis is a novel combination of the established methodologies of slab gel electrophoresis and capillary gel electrophoresis. This new format provides a multilane separation platform with rapid analysis time and e
Autor:
Melinda Szoke, Ágnes Turi, Maria Sasvari-Szekely, Zsolt Csapó, Staffan Eriksson, Maria Staub, Tatjana Spasokoukotskaja, Ildiko Szanto
Publikováno v:
Biochemical Pharmacology. 56:1175-1179
Deoxycytidine kinase (dCK, EC.2.7.1.74), a key enzyme in intracellular metabolism of many antileukemic drugs, was shown to be activated during treatment of lymphocytes by 2-chloro-2'-deoxyadenosine (Cl-dAdo, cladribine), a potent inhibitor of DNA syn
Publikováno v:
Journal of Chromatography A. 817:281-286
A detailed study is presented on the detection of various known point mutations using polymerase chain reaction (PCR) based multi-allele specific amplification (MASA) in conjunction with capillary gel electrophoresis (CGE) separation. The resulting P
Publikováno v:
Nucleosides and Nucleotides. 15:1657-1668
Thymidine (Thd) was phosphorylated to dTTP also at 0°C, both in Ehrlich ascites tumor cells and human tonsillar lymphocytes, but was not incorporated into DNA. The uptake and phosphorylation of 14C-Thd into the pool showed regular kinetics (Km 6, 6
Autor:
Anikó Somogyi, Géza Nagy, Zsolt Ronai, Zsuzsanna Elek, Maria Sasvari-Szekely, Nóra Németh, Nóra Hosszúfalusi, Helga Nemeth
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 10, p e0139519 (2015)
PLoS ONE, Vol 10, Iss 10, p e0139519 (2015)
The absolute or relative lack of insulin is the key factor in the pathogenesis of diabetes mellitus. Although the connection between loss of function mutations of the WFS1 gene and DIDMOAD-syndrome including diabetes mellitus underpins the significan