Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Manabu, Igarashi"'
Autor:
Valter Bergant, Shintaro Yamada, Vincent Grass, Yuta Tsukamoto, Teresa Lavacca, Karsten Krey, Maria‐Teresa Mühlhofer, Sabine Wittmann, Armin Ensser, Alexandra Herrmann, Anja vom Hemdt, Yuriko Tomita, Shutoku Matsuyama, Takatsugu Hirokawa, Yiqi Huang, Antonio Piras, Constanze A Jakwerth, Madlen Oelsner, Susanne Thieme, Alexander Graf, Stefan Krebs, Helmut Blum, Beate M Kümmerer, Alexey Stukalov, Carsten B Schmidt‐Weber, Manabu Igarashi, Thomas Gramberg, Andreas Pichlmair, Hiroki Kato
The SARS‐CoV‐2 infection cycle is a multistage process that relies on functional interactions between the host and the pathogen. Here, we repurposed antiviral drugs against both viral and host enzymes to pharmaceutically block methylation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ad981d0b93c9a8add6f05e47e634f2
https://mediatum.ub.tum.de/doc/1689204/document.pdf
https://mediatum.ub.tum.de/doc/1689204/document.pdf
Autor:
Shiho Torii, Tsogtbaatar Urangoo, Keita Matsuno, Yoshihiro Takadate, Khanui Buyantogtokh, Takeshi Saito, Kosuke Okuya, Ankhanbaatar Ulaankhuu, Khishgee Bodisaikhan, Takanari Hattori, Masatoshi Okamatsu, Manabu Igarashi, Yoshihiro Sakoda, Jargalsaikhan Tserenjav, Damdinjav Batchuluun, Yurie Kida, Hiroshi Kida, Mao Isono, Junki Maruyama, Tsolmon Amartuvshin, Masahiro Sato, Enkhbold Bazarragchaa, Takahiro Hiono, Ayato Takada, Tatsunari Kondoh, Nodoka Kasajima
Publikováno v:
Virus Genes
The circulation of highly pathogenic avian influenza viruses (HPAIVs) of various subtypes (e.g., H5N1, H5N6, H5N8, and H7N9) in poultry remains a global concern for animal and public health. Migratory waterfowls play important roles in the transmissi
Publikováno v:
PeerJ
PeerJ, Vol 9, p e11552 (2021)
PeerJ, Vol 9, p e11552 (2021)
Background Oseltamivir (OTV)-resistant influenza virus exhibits His-to-Tyr mutation at residue 274 (H274Y) in N1 neuraminidase (NA). However, the molecular mechanisms by which the H274Y mutation in NA reduces its binding affinity to OTV have not been
Autor:
Yoshimi Tsuda, Jiro Arikawa, Kumiko Yoshimatsu, Manabu Igarashi, Fumiya Kozawa, Kisho Noda, Kenta Shimizu
Publikováno v:
Viruses
Volume 13
Issue 1
Viruses, Vol 13, Iss 33, p 33 (2021)
Volume 13
Issue 1
Viruses, Vol 13, Iss 33, p 33 (2021)
Severe fever with thrombocytopenia syndrome virus subclone B7 shows strong plaque formation and cytopathic effect induction compared with other subclones and the parental strain YG1. Compared to YG1 and the other subclones, only B7 possesses a single
Autor:
Xinhao Li, Kazuki Takeda, Dhoha Triki, Manabu Igarashi, Tsutomu Tanikawa, Kazuyuki D. Tanaka, Denis Fourches, Shouta M.M. Nakayama, Mayumi Ishizuka, Yoshinori Ikenaka
Publikováno v:
Pesticide biochemistry and physiology. 173:104774
Well-known 4-hydroxycoumarin derivatives, such as warfarin, act as inhibitors of the vitamin K epoxide reductase (VKOR) and are used as anticoagulants. Mutations of the VKOR enzyme can lead to resistance to those compounds. This has been a problem in
Autor:
Keita Matsuno, Hideki Ebihara, Masahiro Kajihara, Ayato Takada, Shiho Torii, Hirofumi Sawa, Manabu Igarashi, Mieko Muramatsu, Nodoka Kasajima, Chihiro Sugimoto, Yongjin Qiu, Kentaro Yoshii, Keita Mizuma, Akina Mori-Kajihara, Ryo Nakao, Naganori Nao
Publikováno v:
mSphere, Vol 3, Iss 3, p e00239-18 (2018)
mSphere, Vol 3, Iss 3 (2018)
mSphere, Vol 3, Iss 3 (2018)
The recent emergence of novel tick-borne RNA viruses has complicated the epidemiological landscape of tick-borne infectious diseases, posing a significant challenge to public health systems that seek to counteract tick-borne diseases. The identificat
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2649 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 12; Pages: 2649
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 12; Pages: 2649
Influenza A virus (IAV) matrix protein 2 (M2) is among the smallest bona fide, hence extensively studied, ion channel proteins. The M2 ion channel activity is not only essential for virus replication, but also involved in modulation of cellular homeo
Autor:
Yoshiharu Matsuura, Manabu Igarashi, Takeshi Kurosu, Ryosuke Suzuki, Mai Shiokawa, Takasuke Fukuhara, Kentaro Yoshii, Hiroshi Aoki, Toru Okamoto, Chikako Ono, Tomokazu Tamura, Hiroyuki Mori, Takeshi Kurihara, Yoshihiro Sakoda, Satomi Yamamoto, Kentaro Uemura
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 6, p e1006475 (2017)
PLoS Pathogens, Vol 13, Iss 6, p e1006475 (2017)
Amphipathic α-helices of exchangeable apolipoproteins have shown to play crucial roles in the formation of infectious hepatitis C virus (HCV) particles through the interaction with viral particles. Among the Flaviviridae members, pestivirus and flav
Autor:
Makoto Kuroda, Asuka Nanbo, Andrea Marzi, Manabu Igarashi, Aaron B. Carmody, Junki Maruyama, Wakako Furuyama, Reiko Yoshida, Ayato Takada, Heinz Feldmann, Hiroko Miyamoto, Rashid Manzoor
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 12, p e1006139 (2016)
PLoS Pathogens, Vol 12, Iss 12, p e1006139 (2016)
Antibody-dependent enhancement (ADE) of Ebola virus (EBOV) infection has been demonstrated in vitro, raising concerns about the detrimental potential of some anti-EBOV antibodies. ADE has been described for many viruses and mostly depends on the cros
Autor:
Naganori Nao, Makoto Kuroda, Keita Matsuno, Ayato Takada, Daisuke Fujikura, Wakako Furuyama, Asako Shigeno, Manabu Igarashi, Rashid Manzoor, Reiko Yoshida, Masahiro Kajihara, Tatsunari Kondoh, Junki Maruyama, Hiroko Miyamoto
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186450 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186450 (2017)
It has been proposed that some non-retroviral RNA virus genes are integrated into vertebrate genomes. Endogenous filovirus-like elements (EFLs) have been discovered in some mammalian genomes. However, their potential roles in ebolavirus infection are