Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jin-Hee Ahn"'
Autor:
Yo-Han Song, Jungwook Kim, Donguk Kang, Chin-Ju Park, Inkyu Lee, Haushabhau S. Pagire, Kang Taek Lee, Jihoon Kang, Jin Hee Ahn
Publikováno v:
Biochemical and Biophysical Research Communications. 527:778-784
Pyruvate dehydrogenase kinase (PDK) controls the activity of pyruvate decarboxylase complex (PDC) by phosphorylating key serine residues on the E1 subunit, which leads to a decreased oxidative phosphorylation in mitochondria. Inhibition of PDK activi
Autor:
Hyemin Kan, Myung Ae Bae, Sung-Hee Cho, Yuji Son, Se Hwan Ahn, Byung Hoi Lee, Dae-Seop Shin, Kyu-Seok Hwang, Jung Yoon Yang, Jin Hee Ahn, Seong Soon Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1285, p 1285 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences
Volume 22
Issue 3
Epilepsy is one of the most common neurological disorders, and it is characterized by spontaneous seizures. In a previous study, we identified 4-(2-chloro-4-fluorobenzyl)-3-(2-thienyl)-1,2,4-oxadiazol-5(4H)-one (GM-90432) as a novel anti-epileptic ag
Autor:
Kyung Hae Jung, Ho Suk Oh, Keon Uk Park, Kyong Hwa Park, Jin-Hee Ahn, Yoon Ji Choi, Jae Hong Seo, Jinho Yoo, Ho Young Kim, In Sil Choi, Suee Lee, Soohyeon Lee, Seok Yun Kang, Ju Won Kim, Hye Sook Kim, Kyung Hun Lee, Kyung Eun Lee, In Hae Park, Hee Jun Kim, Yeon Hee Park
Publikováno v:
Cytokine. 142
Advanced breast cancer frequently metastasizes to the skeleton causing major mobility issues and hazards to quality of life. To manage osteolytic bone metastasis, bone-modifying agents and chemotherapy are recommended as the standard of care. Here, w
Autor:
Sein Kang, Ki Young Kim, Sung-Bum Park, Kyoung Jin Choi, Won Hoon Jung, Yoon-Ju Na, Jin Hee Ahn
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3729, p 3729 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 10
International Journal of Molecular Sciences
Volume 21
Issue 10
Dry eye syndrome is the most common eye disease and it is caused by various reasons. As the balance of the tear film that protects the eyes is broken due to various causes, it becomes impossible to properly protect the eyes. In this study, the protec
Autor:
Byeong Wook Choi, Eun Jung Bae, Seong Soon Kim, Jung Yoon Yang, Jin Hee Ahn, Dae-Seop Shin, Myung Ae Bae, Kyu-Seok Hwang, Byung Hoi Lee, Se Hwan Ahn
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(13)
A series of aryl sulfide derivatives was synthesized and evaluated for their anti-melanogenic activities. Several compounds, including 3e, 3i and 3q exhibited good anti-melanogenic activities. Among the derivatives, compound 3i showed good inhibitory
Autor:
Ho Won Seo, Jeong Hyun Lee, Kwan-Young Jung, Jin Hee Ahn, Byung Ho Lee, Eunyoung Rim, Sung-Bum Park, Ki Young Kim, Haushabhau S. Pagire, Jin Sook Song, Yoon-Ju Na, Won Hoon Jung, Nam Sook Kang, Ju Hwan Bok
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(2)
The 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), a cortisol regenerating enzyme that amplifies tissue glucocorticoid levels, plays an important role in diabetes, obesity, and glaucoma and is recognized as a potential therapeutic target for v
Autor:
Dae-Seop Shin, Kyu-Seok Hwang, Seong Soon Kim, Jin Sil Chae, Geum Ran Kim, Jin Hee Ahn, Myung Ae Bae, Tae-Young Choi, Jung Yoon Yang, Jooyun Lee, Yu-Ri Lee
Publikováno v:
Journal of Dermatological Science. 89:165-171
Background The demand for anti-melanogenic agents is increasing due to the unwanted side effects of current treatments. To find an effective anti-melanogenic agent, we used zebrafish as a whole animal model for phenotype-based drug and cosmetic disco
Autor:
Eun-Hye Lee, Soo Jung Ryu, Dahye Lee, Jin Hee Ahn, Myung Ae Bae, Geum Ran Kim, Don Hang Lee, Minhee Kim, Suvarna H. Pagire, Jin Sook Song, Kyu-Seok Hwang, Sukyung Ahn, Jin Hee Maeng, Haushabhau S. Pagire, Eun Jung Bae
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:529-532
A series of glutamic acid derivatives was synthesized and evaluated for their antioxidant activity and stability. We found several potent and stable glutamic acid derivatives. Among them, compound 12b exhibited good in vitro activity, chemical stabil
Publikováno v:
BMB REPORTS(49): 11
BMB Reports
BMB Reports
Recent evidence indicates that the ephrin receptors and ephrin ligands (Eph/ephrin) expression modulate axonal reorganization and synaptic plasticity in stroke recovery. To investigate the effect of task-specific training (TST) on Eph/ephrin expressi
Autor:
Tae Ho Kim, Sung-E Choi, Eun Sook Hwang, Jong Gab Jung, Jin Hee Ahn, Myung Ae Bae, Ja Young Jeon, Yup Kang, Hana Jeong, Kwan Woo Lee, Sang-A Yi
Publikováno v:
Molecules and Cells
The TAZ activator 2-butyl-5-methyl-6-(pyridine-3-yl)-3-[2'-(1H-tetrazole-5-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine] (TM-25659) inhibits adipocyte differentiation by interacting with peroxisome proliferator-activated receptor gamma. TM-2565