Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jean-Jacques Lafitte"'
Autor:
Marie-Ange Krzewinski-Recchi, Eric Mensier, Olivier Vidal, Anne Harduin-Lepers, Florent Colomb, Philippe Delannoy, Marie Bobowski, Jean-Jacques Lafitte, Sophie Groux-Degroote, Sophie Jaillard
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2013, 457 (1), pp.79-87. ⟨10.1042/BJ20130989⟩
Biochemical Journal, 2013, 457 (1), pp.79-87. ⟨10.1042/BJ20130989⟩
Biochemical Journal, Portland Press, 2013, 457 (1), pp.79-87. ⟨10.1042/BJ20130989⟩
Biochemical Journal, 2013, 457 (1), pp.79-87. ⟨10.1042/BJ20130989⟩
We have shown previously that the pro-inflammatory cytokine TNF (tumour necrosis factor) could drive sLex (sialyl-Lewisx) biosynthesis through the up-regulation of the BX transcript isoform of the ST3GAL4 (ST3 β-galactoside α-2,3-sialyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e9f16c4f5dcef3eae86469951575c8
https://hal.archives-ouvertes.fr/hal-00872219
https://hal.archives-ouvertes.fr/hal-00872219
Autor:
Bruno Mastain, Elizabeth Vinner, Kokou B. Motte, Michel Lhermitte, Franck Broly, D. Marez, Catherine Spire Vayron De La Moureyre, Dany Chevalier, Christian Noel, Jean-Marc Lo Guidice, Serge A. Brique, Christian Libersa, Annie Pol, Jean-Jacques Lafitte, Dominique Turck, René-Marc Flipo, Hervé Debuysere, Jean-Frederic Colombel
Publikováno v:
British Journal of Pharmacology. 125:879-887
1. Characterization of allelic variants of the TPMT gene (TPMT) responsible for changes in TPMT activity, and elucidation of the mechanism by which these alleles act, are required because of the clinical importance of this polymorphism for patients r
Autor:
Sophie Groux-Degroote, Philippe Delannoy, Marie-Ange Krzewinski-Recchi, Anne Harduin-Lepers, Agata Steenackers, Eric Mensier, Fala El Machhour, Sophie Jaillard, Florent Colomb, Jean-Jacques Lafitte
Publikováno v:
Biochimie
Biochimie, Elsevier, 2012, 94 (9), pp.2045-53. ⟨10.1016/j.biochi.2012.05.030⟩
Biochimie, 2012, 94 (9), pp.2045-53. ⟨10.1016/j.biochi.2012.05.030⟩
Biochimie, Elsevier, 2012, 94 (9), pp.2045-53. ⟨10.1016/j.biochi.2012.05.030⟩
Biochimie, 2012, 94 (9), pp.2045-53. ⟨10.1016/j.biochi.2012.05.030⟩
International audience; Bronchial mucins from severely infected patients suffering from lung diseases such as chronic bronchitis or cystic fibrosis exhibit increased amounts of sialyl-Lewis(x) (NeuAcα2-3Galβ1-4[Fucα1-3]GlcNAc-R, sLe(x)) glycan str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672f363852e34a0fbc37cb21b42a8a6c
https://hal.archives-ouvertes.fr/hal-00708570
https://hal.archives-ouvertes.fr/hal-00708570
Autor:
Sophie Jaillard, Elisabeth Courcot, Jean-Jacques Lafitte, Jean-Marc Lo-Guidice, Franck Broly, Eric Mensier, Pirouz Shirali, Philippe Gosset, Nicolas Pottier, Julie Leclerc
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 40(10)
Numerous lung cell lines are currently used as in vitro models for pharmacological and toxicological studies. However, no exhaustive report about the metabolic capacities of these models in comparison with those of lung tissues is available. In the p
Autor:
Nicolas Pottier, Delphine Allorge, Sophie Jaillard, Elisabeth Courcot-Ngoubo Ngangue, Julie Leclerc, Jean-Marc Lo-Guidice, Franck Broly, Christelle Cauffiez, Jean-Jacques Lafitte, Michel Debaert
Publikováno v:
Biochimie. 93(6)
The lung is directly exposed to a wide variety of inhaled toxicants and carcinogens. In order to improve our knowledge of the cellular processing of these compounds in the respiratory tract, we investigated the mRNA expression level of 380 genes enco
Autor:
Sophie Groux-Degroote, Marie-Ange Krzewinski-Recchi, Audrey Vincent, Jean-Jacques Lafitte, Philippe Delannoy, Sylvain Lehoux, Isabelle Van Seuningen, Aurélie Cazet
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2008, 410 (1), pp.213-223. ⟨10.1042/BJ20070958⟩
Biochemical Journal, Portland Press, 2008, 410 (1), pp.213-23. ⟨10.1042/BJ20070958⟩
Biochemical Journal, 2008, 410 (1), pp.213-223. ⟨10.1042/BJ20070958⟩
Biochemical Journal, Portland Press, 2008, 410 (1), pp.213-223. ⟨10.1042/BJ20070958⟩
Biochemical Journal, Portland Press, 2008, 410 (1), pp.213-23. ⟨10.1042/BJ20070958⟩
Biochemical Journal, 2008, 410 (1), pp.213-223. ⟨10.1042/BJ20070958⟩
Bronchial mucins from patients suffering from CF (cystic fibrosis) exhibit glycosylation alterations, especially increased amounts of the sialyl-Lewis(x) (NeuAcalpha2-3Galbeta1-4[Fucalpha1-3]GlcNAc-R) and 6-sulfo-sialyl-Lewis(x) (NeuAcalpha2-3Galbeta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a346bb78125e33cbcbd2a80f6de22c
https://hal.archives-ouvertes.fr/hal-00478849/document
https://hal.archives-ouvertes.fr/hal-00478849/document
Autor:
Genevieve Hennache, Guy Barouh, Jean Jacques Lafitte, Farid Zerimech, Franck Bellon, Nicole Porchet, Malika Balduyck
Publikováno v:
Clinical Chemical Laboratory Medicine. 46
Background Laboratory evaluation of alpha 1-antitrypsin (A1AT) deficiency is generally performed by determination of A1AT concentrations and identification of specific allelic variants by phenotyping. For this purpose, we evaluated a new Hydragel 18
Autor:
Franck Broly, Christelle Cauffiez, Fabien Bonnifet, Michel Lhermitte, Gilles Tournel, Ingrid Billaut-Laden, Delphine Allorge, Jean-Marc Lo-Guidice, Dany Chevalier, Jean-Jacques Lafitte, Eric Mensier
Publikováno v:
Mutation research. 617(1-2)
The CYP2F1 is a human cytochrome P450 that is selectively expressed in lung tissue and involved in the metabolism of various pneumotoxicants with potential carcinogenic effects. In the present study, we report the first systematic investigation of th
Autor:
Jean-Frederic Colombel, Rima Hamdan, Delphine Allorge, Franck Broly, Isabelle Stücker, Sylvie Cénée, Jean-Jacques Lafitte, Sylvie Quaranta, Jean-Marc Lo-Guidice, Dany Chevalier, Christelle Cauffiez, Christian Libersa, Michel Lhermitte
Publikováno v:
Biochemical and biophysical research communications. 317(2)
The human cytochrome CYP2A13, which is mainly expressed in the respiratory tract, has been shown to be highly efficient in vitro in the metabolism of tobacco-smoke carcinogens and procarcinogens such as 4-methylnitroso-1-(3-pyridyl)-1-butanone (NNK).
Autor:
Michel Lhermitte, Franck Broly, Jean-Frederic Colombel, Delphine Allorge, Christelle Cauffiez, Rima Hamdan, Christian Libersa, Jean-Jacques Lafitte, Dany Chevalier, Jean-Marc Lo-Guidice
Publikováno v:
Human mutation. 23(1)
In the present study, we report the first investigation of polymorphisms in the human CYP3A43 gene. A screening for sequence variations in the 5′-flanking and protein coding regions of the CYP3A43 gene was performed by a Polymerase Chain Reaction