Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Huck-Hui Ng"'
Autor:
May Yin Lee, Zhi Han Lim, Yun Shen Chan, Feng Li, Atsushi Suzuki, Edward Kai-Hua Chow, Glenn Kunnath Bonney, John M. Asara, Alicia Stein, Matan Thangavelu Thangavelu, Yoganathan Kanagasundaram, Tan Boon Toh, Guo-Dong Lu, Joanna Z. Yeo, Hong Kee Tan, Kol Jia Yong, Siyu Wang, Justin L. Tan, Chung Yan Leong, Yock Young Dan, Chan Shuo Wu, Giridharan Periyasamy, Zi Hui Tan, Bee Hui Liu, Siming Ma, Wai Leong Tam, Huck-Hui Ng, Guo Hao Ng, Siew Bee Ng, Lissa Hooi, Nikki R. Kong, Tim Chan, Daniel G. Tenen, Li Chai, Kia Ngee Low, Mahmoud A. Bassal, Yue Wu
Publikováno v:
Gastroenterology
Background & Aims Some oncogenes encode transcription factors, but few drugs have been successfully developed to block their activity specifically in cancer cells. The transcription factor SALL4 is aberrantly expressed in solid tumor and leukemia cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d870803882ebda006613d11fea7366ed
https://europepmc.org/articles/PMC7309153/
https://europepmc.org/articles/PMC7309153/
Autor:
Ka Man Yu, Yun-Shen Chan, Huck-Hui Ng, John Soon Yew Lim, Lai Ping Yaw, Chaiyaboot Ariyachet, Deniz Demircioğlu, Chwee Tat Koe, Yee Siang Lim, Einsi Lynn Soe, Hongqing Liang, Kevin Andrew Uy Gonzales, Nur Halisah Binte Jumat, Yock Young Dan, Iwona Szczerbinska, Shu Hui Koh, Zhiping Lu, Cheng Peow Tan, Asim Shabbir, Graham D. Wright, Wei-Quan Tng, Muhammad Nadzim Bin Ramli
Publikováno v:
Gastroenterology. 159:1471-1486.e12
Background & Aims There are few in vitro models for studying the 3-dimensional interactions among different liver cell types during organogenesis or disease development. We aimed to generate hepatic organoids that comprise different parenchymal liver
Autor:
Janet Rossant, Daosheng Huang, Huck-Hui Ng, Tapan Kumar Mistri, Ping Yuan, Guo-Cheng Yuan, Xiaoping Han, Guoji Guo, Paul Robson, Mikael Huss, Lingang Sun, Junfeng Ji, Luca Pinello, Amy Ralston
Publikováno v:
SSRN Electronic Journal.
SUMMARYThe first cellular differentiation event in mouse development leads to the formation of the blastocyst consisting of the inner cell mass (ICM) and an outer functional epithelium called trophectoderm (TE). The lineage specific transcription fac
Autor:
Li-Feng Zhang, Huck-Hui Ng, Amartya Sanyal, Xinyi Lu, Kun Zhang, Xin Chen, Bingqing Lin, Lan-Tian Lai, Ru Hong
Publikováno v:
Scientific Reports
We carried out padlock capture, a high-resolution RNA allelotyping method, to study X chromosome inactivation (XCI). We examined the gene reactivation pattern along the inactive X (Xi), after Xist (X-inactive specific transcript), a prototype long no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56dafa1743b86176911a5a13aa74d83
https://hdl.handle.net/10356/83042
https://hdl.handle.net/10356/83042
Publikováno v:
Cell Cycle. 11:4517-4523
Embryonic stem cells (ESCs) depend on extensive regulatory networks to coordinate their self-renewal and differentiation. The polyamine pathway regulator AMD1 was recently implicated in ESC self-renewal and directed differentiation of ESCs to neural
Autor:
Huck-Hui Ng, Jia-Chi Yeo
Publikováno v:
Cell Research. 23:20-32
The defining features of embryonic stem cells (ESCs) are their self-renewing and pluripotent capacities. Indeed, the ability to give rise into all cell types within the organism not only allows ESCs to function as an ideal in vitro tool to study embr
Autor:
Jonathan Göke, Huck-Hui Ng
Publikováno v:
EMBO reports. 17(8)
The human genome contains millions of fragments from retrotransposons-highly repetitive DNA sequences that were once able to "copy and paste" themselves to other regions in the genome. However, the majority of retrotransposons have lost this capacity
Autor:
Huck-Hui Ng, Kevin Andrew Uy Gonzales
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 80
The repertoire of transcripts encoded by the genome contributes to the diversity of cellular states. Functional genomics aims to comprehensively uncover the roles of these transcripts to reconstruct biological networks and transform this information
Autor:
LeeAnn Ramsay, Xinyi Lu, Pierre-Étienne Jacques, Friedrich Sachs, Guillaume Bourque, Jonathan Göke, Huck-Hui Ng
Publikováno v:
Nature Structural & Molecular Biology. 21:423-425
Human endogenous retrovirus subfamily H (HERVH) is a class of transposable elements expressed preferentially in human embryonic stem cells (hESCs). Here, we report that the long terminal repeats of HERVH function as enhancers and that HERVH is a nucl
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 75:237-244
Pluripotency and self-renewal are the defining traits of embryonic stem cells (ESCs) and this status quo is maintained by the core transcription factors Oct4, Sox2, and Nanog. Genome-wide mapping of the binding sites of these pivotal factors and othe