Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Filhol A."'
Autor:
Jung-Min Kim, Yeon-Suk Yang, Jun Xie, Oksun Lee, JiHea Kim, Jaehyoung Hong, Brigitte Boldyreff, Odile Filhol, Hyonho Chun, Matthew B. Greenblatt, Guangping Gao, Jae-Hyuck Shim
Publikováno v:
Cell Death & Differentiation. 29:1625-1638
Osteocytes play a critical role in bone remodeling through the secretion of paracrine factors regulating the differentiation and activity of osteoblasts and osteoclasts. Sclerostin is a key osteocyte-derived factor that suppresses bone formation and
Autor:
Odile Filhol, Anne-Marie Hesse, Anne-Pascale Bouin, Corinne Albigès-Rizo, Florian Jeanneret, Christophe Battail, Delphine Pflieger, Claude Cochet
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, 2022, 9, ⟨10.3389/fmolb.2022.900947⟩
Frontiers in Molecular Biosciences, 2022, 9, ⟨10.3389/fmolb.2022.900947⟩
International audience; CK2 is a hetero-tetrameric serine/threonine protein kinase made up of two CK2α/αʹ catalytic subunits and two CK2β regulatory subunits. The free CK2α subunit and the tetrameric holoenzyme have distinct substrate specificit
Autor:
Nadia Cherradi, Josiane Denis, Laurent Guyon, Felicitas Rataj, Séverine Planel, Odile Filhol, Jean-Jacques Feige, Caroline Roelants
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2019, ⟨10.1038/s41388-019-0784-8⟩
Oncogene, 2019, ⟨10.1038/s41388-019-0784-8⟩
Oncogene, Nature Publishing Group, 2019, ⟨10.1038/s41388-019-0784-8⟩
Oncogene, 2019, ⟨10.1038/s41388-019-0784-8⟩
International audience; Altered expression of regulatory RNA-binding proteins (RBPs) in cancer leads to abnormal expression of mRNAs encoding many factors involved in cancer hallmarks. While conventional anticancer therapies usually target one pathwa
Autor:
Andreas Christ, Aldo Leal-Egaña, Timothée Vignaud, Caroline Roelants, Gaëlle Letort, Manuel Théry, Odile Filhol, Jean Louis Martiel
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.e16-10-0694⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.E16-10-0694⟩
Molecular Biology of the Cell, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.E16-10-0694⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.e16-10-0694⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.E16-10-0694⟩
Molecular Biology of the Cell, 2017, 28 (12), pp.1612-1621. ⟨10.1091/mbc.E16-10-0694⟩
Normal and transformed motile cells follow a common trend in which size and contractile forces are negatively correlated with cell speed. However, tumorigenic factors amplify the preexisting population heterogeneity and lead some cells to exhibit bio
Autor:
Joanne Young, Gaëlle Letort, Mithila Burute, Thomas Bessy, Sandrine Truchet, Odile Filhol, Qingzong Tseng, Guillaume Blin, Sally Lowell, Manuel Théry, Magali Prioux
Publikováno v:
Developmental Cell
Developmental Cell, 2017, 40 (2), pp.168-184. ⟨10.1016/j.devcel.2016.12.004⟩
Developmental Cell, Elsevier, 2017, 40 (2), pp.168-184. ⟨10.1016/j.devcel.2016.12.004⟩
Burute, M, Prioux, M, Blin, G, Truchet, S, Letort, G, Tseng, Q, Bessy, T, Lowell, S, Young, J, Filhol, O & Théry, M 2017, ' Polarity reversal by centrosome repositioning primes cell scattering during epithelial-to-mesenchymal transition ', Developmental Cell, vol. 40, no. 2, pp. 168-184 . https://doi.org/10.1016/j.devcel.2016.12.004
Developmental Cell, 2017, 40 (2), pp.168-184. ⟨10.1016/j.devcel.2016.12.004⟩
Developmental Cell, Elsevier, 2017, 40 (2), pp.168-184. ⟨10.1016/j.devcel.2016.12.004⟩
Burute, M, Prioux, M, Blin, G, Truchet, S, Letort, G, Tseng, Q, Bessy, T, Lowell, S, Young, J, Filhol, O & Théry, M 2017, ' Polarity reversal by centrosome repositioning primes cell scattering during epithelial-to-mesenchymal transition ', Developmental Cell, vol. 40, no. 2, pp. 168-184 . https://doi.org/10.1016/j.devcel.2016.12.004
International audience; During epithelial-to-mesenchymal transition (EMT), cells lining the tissue periphery break up their cohesion to migrate within the tissue. This dramatic reorganization involves a poorly characterized reorientation of the apico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f83ba819f43dbc8f371dd82801eb417
https://www.hal.inserm.fr/inserm-02353821
https://www.hal.inserm.fr/inserm-02353821
Autor:
Laurent Poirot, Julien Valton, Valérie Guyot, Alan Maréchal, Philippe Duchateau, Alexandre Juillerat, Aymeric Duclert, Jean-Marie Filhol
Publikováno v:
Molecular Therapy
The adoptive transfer of chimeric antigen receptor (CAR) T cell represents a highly promising strategy to fight against multiple cancers. The clinical outcome of such therapies is intimately linked to the ability of effector cells to engraft, prolife
Autor:
Alexandre Benmerah, Estelle Escudier, Christine Bole-Feysot, Véronique Baudouin, Thérèse Reboul, Patrick Nitschké, Marie Legendre, Marion Delous, Sophie Saunier, Meriem Garfa-Traore, Rebecca Ryan, Madeline Louise Reilly, Marion Failler, Serge Amselem, Emilie Filhol
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2018, 27 (2), pp.266-282. ⟨10.1093/hmg/ddx396⟩
Human Molecular Genetics, 2018, 27 (2), pp.266-282. ⟨10.1093/hmg/ddx396⟩
Human Molecular Genetics, Oxford University Press (OUP), 2018, 27 (2), pp.266-282. ⟨10.1093/hmg/ddx396⟩
Human Molecular Genetics, 2018, 27 (2), pp.266-282. ⟨10.1093/hmg/ddx396⟩
International audience; A child presenting with Mainzer-Saldino syndrome (MZSDS), characterized by renal, retinal and skeletal involvements, was also diagnosed with lung infections and airway ciliary dyskinesia. These manifestations suggested dysfunc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beac4d6c54ab4a1fabc358123b4aa12d
https://www.hal.inserm.fr/inserm-02263788
https://www.hal.inserm.fr/inserm-02263788
Autor:
Odile Filhol-Cochet, Frédérique Kermarrec, Maxime Legues, Xavier Gidrol, Guillaume Laffitte, Christophe A. Marquette, Jean-Pierre Alcaraz, Olivier Nicoud, Nathalie Picollet-D'hahan, Florence Rivera, Isabelle Vilgrain, Lavinia Liguori, Jacques Thélu, Patricia Obeid, Donald K. Martin, Ali Bouamrani, Sophie Gerbaud, Benoit Gilquin, Thibaud Moufle-Milot, Adrien Mombrun, Cristina Belda Marin, Axel Tollance
Publikováno v:
The EuroBiotech Journal
The EuroBiotech Journal, Sciendo, 2018, 2 (4), pp.180-195. ⟨10.2478/ebtj-2018-0048⟩
The EuroBiotech Journal, Vol 2, Iss 4, Pp 180-191 (2018)
The EuroBiotech Journal, 2018, 2 (4), pp.180-195. ⟨10.2478/ebtj-2018-0048⟩
The EuroBiotech Journal, Sciendo, 2018, 2 (4), pp.180-195. ⟨10.2478/ebtj-2018-0048⟩
The EuroBiotech Journal, Vol 2, Iss 4, Pp 180-191 (2018)
The EuroBiotech Journal, 2018, 2 (4), pp.180-195. ⟨10.2478/ebtj-2018-0048⟩
We report our approach to creating a microfluidic chip (namely UroLOC) that mimics the acinar/tubular structure and the luminal microenvironment of exocrine glands. The chip utilises a nanostructured membrane that is designed to provide a 3-dimension
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb8026ac981f76f476dab981490f056
https://hal.archives-ouvertes.fr/hal-02094038/document
https://hal.archives-ouvertes.fr/hal-02094038/document
Publikováno v:
Cellular and Molecular Life Sciences. 72:3305-3322
Structurally, protein kinase CK2 consists of two catalytic subunits (α and α') and two regulatory subunits (β), which play a critical role in targeting specific CK2 substrates. Compelling evidence shows the complexity of the CK2 cellular signaling
Autor:
Francois Chatelain, Sandra Boccard, Julien Reboud, Béatrice Schaack, François Berger, Brigitte Fouque, Stéphanie Combe, Odile Filhol-Cochet
We have developed a "DropChip" microarray for multiplexed cell-based assays to perform information-rich high-throughput screening. This microarray features cell culture nanoliter droplets on a glass slide; the culture's size, shape, and location are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee08a1521bdb5248b57b80ba1f0a341f
https://doi.org/10.1385/nbt:1:2:183
https://doi.org/10.1385/nbt:1:2:183