Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Balázs Győrffy"'
Autor:
Csaba Miskey, Lacramioara Botezatu, Nuri A. Temiz, Andreas Gogol-Döring, Áron Bartha, Balázs Győrffy, David A. Largaespada, Zoltán Ivics, Attila Sebe
Publikováno v:
Molecular Cancer Research. 20:1502-1515
Metastasis, a complex, multistep process, is responsible for the overwhelming majority of cancer-related deaths. Despite its devastating consequences, it is not possible to effectively treat cancer that has spread to vital organs, the mechanisms lead
Autor:
János Tibor Fekete, Balázs Győrffy
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1508
The overall response rate to fluoropyrimidine monotherapy in colorectal cancer (CRC) is limited. Transcriptomic datasets of CRC patients treated with 5-fluorouracil (5FU) could assist in the identification of clinically useful biomarkers. In this res
Autor:
Hannah N. Bell, Amanda K. Huber, Rashi Singhal, Navyateja Korimerla, Ryan J. Rebernick, Roshan Kumar, Marwa O. El-derany, Peter Sajjakulnukit, Nupur K. Das, Samuel A. Kerk, Sumeet Solanki, Jadyn G. James, Donghwan Kim, Li Zhang, Brandon Chen, Rohit Mehra, Timothy L. Frankel, Balázs Győrffy, Eric R. Fearon, Marina Pasca di Magliano, Frank J. Gonzalez, Ruma Banerjee, Daniel R. Wahl, Costas A. Lyssiotis, Michael Green, Yatrik M. Shah
Publikováno v:
Cell metabolism. 35(1)
Effective therapies are lacking for patients with advanced colorectal cancer (CRC). The CRC tumor microenvironment has elevated metabolic waste products due to altered metabolism and proximity to the microbiota. The role of metabolite waste in tumor
Autor:
Luca Hegedüs, Elisabeth Livingstone, Ágnes Bánkfalvi, Jan Viehof, Ágnes Enyedi, Ágnes Bilecz, Balázs Győrffy, Marcell Baranyi, Anna-Mária Tőkés, Jeovanis Gil, György Marko-Varga, Klaus G. Griewank, Lisa Zimmer, Renáta Váraljai, Antje Sucker, Anne Zaremba, Dirk Schadendorf, Clemens Aigner, Balázs Hegedüs
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3324
OA Förderung 2022 PMCA4 is a critical regulator of Ca2+ homeostasis in mammalian cells. While its biological and prognostic relevance in several cancer types has already been demonstrated, only preclinical investigations suggested a metastasis suppr
Autor:
Andrea Ladányi, Erzsébet Rásó, Tamás Barbai, Laura Vízkeleti, László G. Puskás, Szonja A. Kovács, Balázs Győrffy, József Tímár
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2704
We developed a human melanoma model using the HT168-M1 cell line to induce IFN-α2 resistance in vitro (HT168-M1res), which was proven to be maintained in vivo in SCID mice. Comparing the mRNA profile of in vitro cultured HT168-M1res cells to its sen
Autor:
Iris Kahl, Julian Mense, Christopher Finke, Anna‐Lena Boller, Clara Lorber, Balázs Győrffy, Burkhard Greve, Martin Götte, Nancy A Espinoza‐Sánchez
Publikováno v:
Journal of cellular biochemistryREFERENCES. 123(3)
Breast cancer is the third most common type of cancer diagnosed. Cell cycle is a complex but highly organized and controlled process, in which normal cells sense mitogenic growth signals that instruct them to enter and progress through their cell cyc
Autor:
Jan Winter, Chidiebere U. Awah, Markella Zannikou, Denise M. Scholtens, Regina T. Martuscello, Edgar Gonzalez-Buendia, Li Chen, Patrick D. Hsu, Silvana Konerman, Atique Ahmed, Roger Stupp, Daniel Zhang, Dou Yu, Irina V. Balyasnikova, Louisa Warnke, Mukesh Bansal, Balázs Győrffy, Cheol Park, Kirsten Bell Burdett, Adam M. Sonabend, Meeki Lad, Aayushi Mahajan, Eric Feldstein
Publikováno v:
Oncogene
Oncogene, vol 39, iss 27
Oncogene, vol 39, iss 27
Topoisomerase II poisons are one of the most common class of chemotherapeutics used in cancer. We and others had shown that a subset of glioblastomas (GBM), the most malignant of all primary brain tumors in adults, are responsive to TOP2 poisons. To
Autor:
Ning Shen, Panagiotis Papageorgis, Arthur W. Lambert, Delia Lopez, Chen Khuan Wong, Sait Ozturk, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Sam Thiagalingam, Hui Feng
Publikováno v:
Mol Cancer Res
Deciphering molecular targets to enhance sensitivity to chemotherapy is becoming a priority for effectively treating cancers. Loss of function mutations of SMAD4 in colon cancer are associated with metastatic progression and resistance to 5-fluoroura
Autor:
Jing Chen, Liqing Li, Cai Huang, Haining Zhu, Vesa P. Hytönen, Olli T. Pentikäinen, Sampo Kukkurainen, Zbigniew Baster, Zenon Rajfur, Balázs Győrffy
Publikováno v:
The FASEB Journal. 34:2227-2237
Cyanidin-3-glucoside (C3G) is a natural pigment, found in many colorful fruits and vegetables. It has many health benefits, including anti-inflammation, cancer prevention, and anti-diabetes. Although C3G is assumed to be an antioxidant, it has been r
Autor:
Zacharias Drosos, Ahmed El-Balat, Balázs Győrffy, David G. Huntsman, Lars Hanker, Achim Rody, Thomas Karn, Heidrun Gevensleben, Michael S. Anglesio, Stefan Kommoss, Sven Becker, Uwe Holtrich
Publikováno v:
Virchows Archiv. 476:855-862
Acid ceramidase (ASAH1) is a key player in sphingolipid metabolism and signaling. It has prognostic value for several cancers, but histotype-specific analyses of ovarian cancer are not yet available. We used three retrospective TMA cohorts encompassi