Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Antja-Voy Hartley"'
Autor:
Antja-Voy Hartley, Ahmad R. Safa, Yunlong Liu, Lakshmi Prabhu, Han Wei, Tao Lu, Aishat Motolani, Guanglong Jiang
Publikováno v:
Genes and Diseases, Vol 9, Iss 2, Pp 285-287 (2022)
Autor:
Tao Lu, Steven Sun, Mengyao Sun, Guanglong Jiang, Yunlong Liu, Rasika Mundade, Han Wei, Benlian Wang, Antja-Voy Hartley
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
The multifunctional protein Y-box binding protein 1 (YBX1), is a critical regulator of transcription and translation, and is widely recognized as an oncogenic driver in several solid tumors, including colorectal cancer (CRC). However, very little is
Autor:
Matthew Martin, Rasika Mundade, Antja-Voy Hartley, Guanglong Jiang, Jiamin Jin, Steven Sun, Ahmad Safa, George Sandusky, Yunlong Liu, Tao Lu
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2732
Since nuclear factor (NF) κB plays pivotal roles in inflammation and cancer, understanding its regulation holds great promise for disease therapy. Using the powerful validation-based insertional mutagenesis (VBIM) technique established by us previou
Publikováno v:
Cell Cycle
Epigenetic modulators play pivotal roles in directing gene expression for the maintenance of normal cellular functions. However, when these modulators are aberrantly regulated, this can result in a variety of disease states, including cancer. One cla
Autor:
Steven Sun, Tao Lu, Han Wei, Matthew Martin, Benlian Wang, Yunlong Liu, Ahmad R. Safa, Guanglong Jiang, Antja-Voy Hartley, Mengyao Sun, Lakshmi Prabhu
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3684, p 3684 (2020)
Volume 21
Issue 10
International Journal of Molecular Sciences, Vol 21, Iss 3684, p 3684 (2020)
Volume 21
Issue 10
The overexpression of PRMT5 is highly correlated to poor clinical outcomes for colorectal cancer (CRC) patients. Importantly, our previous work demonstrated that PRMT5 overexpression could substantially augment activation of the nuclear factor kappa
Role of Novel Serine 316 Phosphorylation of the p65 Subunit of NF-κB in Differential Gene Regulation
Publikováno v:
Journal of Biological Chemistry. 290:20336-20347
Nuclear factor κB (NF-κB) is a central coordinator in immune and inflammatory responses. Constitutive NF-κB is often found in some types of cancers, contributing to oncogenesis and tumor progression. Therefore, knowing how NF-κB is regulated is i
Autor:
Yishi Yin, James J. Lah, Kerry J. Ressler, Antja-Voy Hartley, Xinping Huang, Jeremy H. Herskowitz
Publikováno v:
Journal of Virological Methods. 193:270-277
The adeno-associated virus (AAV) is one of the most useful viral vectors for gene delivery for both in vivo and in vitro applications. A variety of methods have been established to produce and characterize recombinant AAV (rAAV) vectors; however most
Autor:
Laiqing Hua, Matthew Martin, Antja Voy Hartley, Guanglong Jiang, Yunlong Liu, Tao Lu, Benlian Wang, Lakshmi Prabhu, Han Wei
Publikováno v:
The Journal of biological chemistry. 292(8)
Y box protein 1 (YBX1) is a well known oncoprotein that has tumor-promoting functions. YBX1 is widely considered to be an attractive therapeutic target in cancer. To develop novel therapeutics to target YBX1, it is of great importance to understand h
Publikováno v:
Genesdiseases. 2(3)
Y box binding protein-1 (YBX1) belongs to a DNA- and RNA-binding family of transcription factors, containing the highly conserved cold shock domain (CSD). YBX1 is involved in a number of cellular functions including transcription, translation, DNA da