Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ansuman T. Satpathy"'
Autor:
Joy A. Pai, Ansuman T. Satpathy
Publikováno v:
Nat Methods
T cells express T cell receptors (TCRs) composed of somatically recombined TCRα and TCRβ chains, which mediate recognition of major histocompatibility complex (MHC)-antigen complexes and drive the antigen-specific adaptive immune response to pathog
Autor:
Bence Daniel, Julia A. Belk, Stefanie L. Meier, Andy Y. Chen, Katalin Sandor, Zsolt Czimmerer, Zsofia Varga, Krisztian Bene, Frank A. Buquicchio, Yanyan Qi, Hugo Kitano, Joshua R. Wheeler, Deshka S. Foster, Michael Januszyk, Michael T. Longaker, Howard Y. Chang, Ansuman T. Satpathy
Publikováno v:
Molecular cell. 83(1)
Cell cycle (CC) facilitates cell division via robust, cyclical gene expression. Protective immunity requires the expansion of pathogen-responsive cell types, but whether CC confers unique gene expression programs that direct the subsequent immunologi
Autor:
Jo Anne Stratton, Sorana Morrissy, Nizar J. Bahlis, Weiqiang Zhou, Ansuman T. Satpathy, Sarthak Sinha, Hongkai Ji, Arzina Jaffer, Jeff Biernaskie
Publikováno v:
Genomics, Proteomics & Bioinformatics
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 172-190 (2021)
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 172-190 (2021)
How distinct transcriptional programs are enacted to generate cellular heterogeneity and plasticity, and enable complex fate decisions are important open questions. One key regulator is the cell’s epigenome state that drives distinct transcriptiona
Publikováno v:
Molecular Cell. 81:2272-2274
Pritykin et al. (2021) establish a comprehensive chromatin atlas of CD8+ T cell dysfunction in chronic viral infection and cancer via analysis of bulk and single-cell ATAC-seq datasets across immune challenges. These results unify the classification
Autor:
Mark Y. Jeng, Ansuman T. Satpathy, Howard Y. Chang, Maxwell R. Mumbach, Anne Lynn S. Chang, Jeffrey M. Granja
Publikováno v:
Journal of Investigative Dermatology. 139:605-614
The vast majority of polymorphisms for human dermatologic diseases fall in noncoding DNA regions, leading to difficulty interpreting their functional significance. Recent work using chromosome conformation capture technology in combination with chrom
Autor:
Jimmy K. Guo, Ansuman T. Satpathy, Yanyan Qi, Paul A. Khavari, M. Ryan Corces, Maninjay K. Atianand, Ryan A. Flynn, Bryan H. Louie, William J. Greenleaf, Howard Y. Chang, Steven E. Artandi, Jeffrey M. Granja, Katherine A. Fitzgerald, Adam J. Rubin, Zhaozhao Jiang, Caitlin M. Roake, Maxwell R. Mumbach, David Gennert, Shadi Shams
Publikováno v:
Nature methods. 16(6)
Modular domains of long non-coding RNAs can serve as scaffolds to bring distant regions of the linear genome into spatial proximity. Here, we present HiChIRP, a method leveraging bio-orthogonal chemistry and optimized chromosome conformation capture
Autor:
Howard Y. Chang, Maxwell R. Mumbach, Anshul Kundaje, Maya Kasowski, Kathleen S. Montine, Viviana I. Risca, Beijing Wu, Ansuman T. Satpathy, Alexandro E. Trevino, M. Ryan Corces, Thomas J. Montine, Arwa Kathiria, Adam J. Rubin, Peyton Greenside, Paul A. Khavari, Emily G. Hamilton, William J. Greenleaf, Nicholas A Sinnott-Armstrong, Sam Vesuna, Ava C. Carter, Lisa A. Orloff, Seung Woo Cho
Publikováno v:
Nature methods. 14(10)
We present Omni-ATAC, an improved ATAC-seq protocol for chromatin accessibility profiling that works across multiple applications with substantial improvement of signal-to-background ratio and information content. The Omni-ATAC protocol enables chrom
Autor:
Howard Y. Chang, Rajarshi P. Ghosh, Seung Woo Cho, Ying Shen, Jan Liphardt, William J. Greenleaf, Ulrike M. Litzenburger, Jennifer A. Doudna, Ansuman T. Satpathy, Jason D. Buenrostro, Xingqi Chen, Alexandra East-Seletsky, Ava C. Carter, Will E Draper
Publikováno v:
Nature methods. 13(12)
Spatial organization of the genome plays a central role in gene expression, DNA replication, and repair. But current epigenomic approaches largely map DNA regulatory elements outside of the native context of the nucleus. Here we report assay of trans
Autor:
Paul A. Khavari, Howard Y. Chang, Ansuman T. Satpathy, Adam J. Rubin, William J. Greenleaf, Muthukumar Ramanathan, K. Parker
Publikováno v:
Journal of Investigative Dermatology. 139:S63
Autor:
S. Reddy, Duy C. Tran, Anne Lynn S. Chang, Mark Y. Jeng, John G.D. Cannon, Shaoying Li, A. Colevas, Kavita Y. Sarin, Ansuman T. Satpathy, K. Yost, Kerri E. Rieger
Publikováno v:
Journal of Investigative Dermatology. 139:S92