Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alex M. Jaeger"'
Publikováno v:
Nature structural & molecular biology
Heat Shock Transcription Factor (HSF) family members function in stress protection and in human disease including proteopathies, neurodegeneration and cancer. The mechanisms that drive distinct post-translational modifications, co-factor recruitment
Publikováno v:
The Journal of biological chemistry, vol 289, iss 44
The heat shock transcription factor 1 (HSF1) activates expression of a variety of genes involved in cell survival, including protein chaperones, the protein degradation machinery, anti-apoptotic proteins, and transcription factors. Although HSF1 acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92f998f198fc6d24471d256d6f279e6
https://europepmc.org/articles/PMC4215228/
https://europepmc.org/articles/PMC4215228/
Publikováno v:
G3: Genes|Genomes|Genetics
Human heat shock transcription factor 1 (HSF1) promotes the expression of stress-responsive genes and is a critical factor for the cellular protective response to proteotoxic and other stresses. In response to stress, HSF1 undergoes a transition from
Publikováno v:
The Journal of biological chemistry. 286(36)
Morphine and other opiates mediate their effects through activation of the μ-opioid receptor (MOR), and regulation of the MOR has been shown to critically affect receptor responsiveness. Activation of the MOR results in receptor phosphorylation, β-
Autor:
Daniel W. Neef, Eileen T. Burchfiel, Rocío Gómez-Pastor, Donald C. Lo, Alex M. Jaeger, Spencer U. McKinstry, Cagla Eroglu, Christopher A. Ross, Dennis J. Thiele, Argenia Doss, Elisa Cabiscol, Alejandro Aballay, Sergey S Akimov
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications
Repositorio Abierto de la UdL
Universitad de Lleida
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
instname
Nature Communications
Repositorio Abierto de la UdL
Universitad de Lleida
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Huntington's Disease (HD) is a neurodegenerative disease caused by poly-glutamine expansion in the Htt protein, resulting in Htt misfolding and cell death. Expression of the cellular protein folding and pro-survival machinery by heat shock transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06550914296ed079842959947de432bf
http://hdl.handle.net/10459.1/59330
http://hdl.handle.net/10459.1/59330