Zobrazeno 1 - 10
of 606
pro vyhledávání: '"A. Dougherty"'
Autor:
Luisa Biebach, Sandra Cindrić, Julia Koenig, Isabella Aprea, Gerard W. Dougherty, Johanna Raidt, Diana Bracht, Renate Ruppel, Jens Schreiber, Rim Hjeij, Heike Olbrich, Heymut Omran
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 67:409-413
Autor:
Matthew A. Deragon, William D. McCaig, Phillip V. Truong, Kevin R. Metz, Katherine A. Carron, Keven J. Hughes, Angeleigh R. Knapp, Molly J. Dougherty, Timothy J. LaRocca
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8609
Apoptosis and necroptosis overlap in their initial signaling but diverge to produce non-inflammatory and pro-inflammatory outcomes, respectively. High glucose pushes signaling in favor of necroptosis producing a hyperglycemic shift from apoptosis to
Publikováno v:
Molecular Biology of the Cell. 34
Lithium is known to lengthen cilia across cell types. Using the organism model organism Chlamydomonas, we confirm that this elongation occurs independent of protein synthesis and show that it is also independent of the Golgi. Additionally, we find th
Autor:
Puhua Niu, Maria J. Soto, Shuai Huang, Byung-Jun Yoon, Edward R. Dougherty, Francis J. Alexander, Ian Blaby, Xiaoning Qian
Publikováno v:
Journal of Computational Biology.
TRIMER, Transcription Regulation Integrated with MEtabolic Regulation, is a genome-scale modeling pipeline targeting at metabolic engineering applications. Using TRIMER, regulated metabolic reactions can be effectively predicted by integrative modeli
Autor:
Kantiya Jindachomthong, Chengran Yang, Yuegao Huang, Daniel Coman, Maximiliano Rapanelli, Fahmeed Hyder, Joseph Dougherty, Luciana Frick, Christopher Pittenger
Publikováno v:
Frontiers in Molecular Neuroscience. 15
IntroductionAn inactivating mutation in the histidine decarboxylase gene (Hdc) has been identified as a rare but high-penetrance genetic cause of Tourette syndrome (TS). TS is a neurodevelopmental syndrome characterized by recurrent motor and vocal t
Autor:
Alexei J, Stuckel, Shuai, Zeng, Zhen, Lyu, Wei, Zhang, Xu, Zhang, Urszula, Dougherty, Reba, Mustafi, Tripti, Khare, Qiong, Zhang, Trupti, Joshi, Marc, Bissonnette, Sharad, Khare
Publikováno v:
Epigenetics. 18
Sprouty4 (SPRY4) has been frequently reported as a tumor suppressor and is therefore downregulated in various cancers. For the first time, we report that SPRY4 is epigenetically upregulated in colorectal cancer (CRC). In this study, we explored DNA m
Autor:
Wenting Ma, Matthew R. Sapio, Allison P. Manalo, Dragan Maric, Mary Kate Dougherty, Taichi Goto, Andrew J. Mannes, Michael J. Iadarola
Publikováno v:
Frontiers in Molecular Neuroscience. 15
Primary afferent neurons of the dorsal root ganglia (DRG) transduce peripheral nociceptive signals and transmit them to the spinal cord. These neurons also mediate analgesic control of the nociceptive inputs, particularly through the μ-opioid recept
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5541
We describe and analyze a computational model of neural circuits in the mammalian spinal cord responsible for generating and shaping locomotor-like oscillations. The model represents interacting populations of spinal neurons, including the neurons th
Autor:
Kyra Dougherty, Katalin A. Hudak
Publikováno v:
Phytochemistry. 202
Ribosome inactivating proteins (RIPs) are rRNA N-glycosylases (EC 3.2.2.22) best known for hydrolyzing an adenine base from the conserved sarcin/ricin loop of ribosomal RNA. Protein translation is inhibited by ribosome depurination; therefore, RIPs a
Autor:
Rebecca Barok, Brendan Dougherty
Publikováno v:
The FASEB Journal. 36