Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yasuo Urata"'
Autor:
Shuhei Osaki, Futoshi Uno, Ryosuke Yoshida, Aki Yoshida, Toshiyoshi Fujiwara, Hiroshi Tazawa, Yuuri Hashimoto, Shuya Yano, Tsuyoshi Sasaki, Joe Hasei, Toshifumi Ozaki, Yasuo Urata, Toshiyuki Kunisada, Shunsuke Kagawa
Publikováno v:
Gene Therapy. 20:112-118
Adenovirus serotype 5 (Ad5) is frequently used as an effective vector for induction of therapeutic transgenes in cancer gene therapy or of tumor cell lysis in oncolytic virotherapy. Ad5 can infect target cells through binding with the coxsackie and a
Autor:
Hiroshi Aoyama, Takaji Wakita, Mika Okamoto, Kouichi Watashi, Masanori Baba, Takayuki Hamasaki, Yasuo Urata, Mohammed T.A. Salim, Kazuyuki Sugita, Yuichi Hashimoto
Publikováno v:
Biochemical and Biophysical Research Communications. 415:714-719
A number of novel phenanthridinone derivatives were examined for their inhibitory effect on hepatitis C virus (HCV) replication in Huh-7 cells harboring self-replicating subgenomic viral RNA replicons with a luciferase reporter (LucNeo#2). The activi
Autor:
Hiroyuki Mizuguchi, Satoru Kyo, Daiju Ichimaru, Noriaki Tanaka, Shunsuke Kagawa, Futoshi Uno, Toshiyoshi Fujiwara, Yuichi Watanabe, Yoshiyuki Hashimoto, Hitoshi Kawamura, Toru Kojima, Yasuo Urata
Publikováno v:
Oncogene. 29:1145-1154
Malignant pleural mesothelioma (MPM) is a highly aggressive tumor that is related to asbestos exposure. MPM is characterized by rapid and diffuse local growth in the thoracic cavity, and it has a poor prognosis because it is often refractory to conve
Autor:
Hiroyuki Kishimoto, Toshiya Fujiwara, Takanori Watanabe, Toshiyoshi Fujiwara, Masahiko Nishizaki, Masaki Taki, Noriaki Tanaka, Masayoshi Hioki, Yoshikatsu Endo, Shunsuke Kagawa, Yasuo Urata
Publikováno v:
Experimental Cell Research. 312:256-265
Replication-competent oncolytic viruses are being developed for human cancer therapy. We previously reported that an attenuated adenovirus OBP-301 (Telomelysin), in which the human telomerase reverse transcriptase promoter element drives expression o
Autor:
Toshiyoshi Fujiwara, Yasuo Urata, Yuichi Watanabe, Hitoshi Kawamura, Noriaki Tanaka, Shunsuke Kagawa, Katsuyuki Nagai, Yuuri Hashimoto
Publikováno v:
Cancer gene therapy. 19(11)
Replication-selective oncolytic viruses are being developed for human cancer therapy. We previously developed an attenuated adenovirus (OBP-301, Telomelysin), in which the human telomerase reverse transcriptase promoter element drives expression of E
Autor:
Toshiyoshi Fujiwara, Hiromi Kumon, Takashi Saika, Yasuo Urata, Masami Watanabe, Peng Huang, Jie Chen, Yuji Kashiwakura, Yasutomo Nasu, Haruki Kaku
Publikováno v:
Cancer gene therapy. 17(7)
OBP-301 (a telomerase-specific, replication-competent adenovirus with hTERT promoter) was constructed in a previous study and it showed a strong anticancer effect by inducing cell lysis in human lung and prostate cancer cells. This study investigated