Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jan Trnka"'
Autor:
Michal Anděl, Tomáš Urban, G. Hege Thoresen, Petr Waldauf, František Duška, Nils Gunnar Løvsletten, Vladimír Frič, Jan Trnka, Adéla Krajčová, Moustafa Elkalaf
Publikováno v:
Critical care medicine. 46(3)
Objectives Propofol may adversely affect the function of mitochondria and the clinical features of propofol infusion syndrome suggest that this may be linked to propofol-related bioenergetic failure. We aimed to assess the effect of therapeutic propo
Autor:
Kateřina Jiroutková, Jan Gojda, Adéla Krajčová, Jakub Žiak, Martin Kalous, Jan Trnka, František Duška, Michal Fric, Valér Džupa, Jana Tůmová
Publikováno v:
JPEN. Journal of parenteral and enteral nutrition. 41(7)
BACKGROUND Functional mitochondria in skeletal muscle of patients with protracted critical illness and intensive care unit-acquired weakness are depleted, but remaining mitochondria have increased functional capacities of respiratory complexes II and
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0161413 (2016)
PLoS ONE, Vol 11, Iss 8, p e0161413 (2016)
Methyltriphenylphosphonium (TPMP) salts have been widely used to measure the mitochondrial membrane potential and the triphenylphosphonium (TPP+) moiety has been attached to many bioactive compounds including antioxidants to target them into mitochon
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121837 (2015)
PLoS ONE
PLoS ONE
Background The lipophilic positively charged moiety of triphenylphosphonium (TPP+) has been used to target a range of biologically active compounds including antioxidants, spin-traps and other probes into mitochondria. The moiety itself, while often
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e70772 (2013)
PLoS ONE, Vol 8, Iss 8, p e70772 (2013)
BACKGROUND: Substituting galactose for glucose in cell culture media has been suggested to enhance mitochondrial metabolism in a variety of cell lines. We studied the effects of carbohydrate availability on growth, differentiation and metabolism of C