Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jorge Cruz-Reyes"'
Autor:
Jorge Cruz-Reyes, Michael W. Gray
This volume focuses on mitochondrial RNA metabolism, emphasizing recent discoveries and technological advances in this fast moving area that increase our understanding of mitochondrial gene function. Topics addressed include the interplay of mitochon
Autor:
Suzanne M. McDermott, Z. Hong Zhou, H. Ulrich Göringer, Alena Zíková, Kenneth Stuart, Igor Cestari, Reza Salavati, Stephen L. Hajduk, Julius Lukeš, Ruslan Aphasizhev, Dmitri A. Maslov, Jason Carnes, Achim Schnaufer, Inna Aphasizheva, Larry Simpson, Torsten Ochsenreiter, Jorge Cruz-Reyes, Laurie K. Read, André Schneider, Susan Madison-Antenucci, Vyacheslav Yurchenko, Liye Zhang, Juan D. Alfonzo, Sara L. Zimmer
Publikováno v:
Aphasizheva, I, Alfonzo, J, Carnes, J, Cestari, I, Cruz-Reyes, J, Göringer, H U, Hajduk, S, Lukeš, J, Madison-Antenucci, S, Maslov, D A, McDermott, S M, Ochsenreiter, T, Read, L K, Salavati, R, Schnaufer, A, Schneider, A, Simpson, L, Stuart, K, Yurchenko, V, Zhou, Z H, Zíková, A, Zhang, L, Zimmer, S & Aphasizhev, R 2020, ' Lexis and grammar of mitochondrial RNA processing in Trypanosomes ', Trends in Parasitology, vol. 36, no. 4, pp. 337-355 . https://doi.org/10.1016/j.pt.2020.01.006
Trends in parasitology, vol 36, iss 4
Trends in parasitology, vol 36, iss 4
Trypanosoma brucei spp. cause African human and animal trypanosomiasis, a burden on health and economy in Africa. These hemoflagellates are distinguished by a kinetoplast nucleoid containing mitochondrial DNAs of two kinds: maxicircles encoding ribos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8171b9f7520b2af84d845636eb4343d1
https://hdl.handle.net/20.500.11820/def562e4-fc49-427d-84a3-da811b3f009b
https://hdl.handle.net/20.500.11820/def562e4-fc49-427d-84a3-da811b3f009b
Autor:
Jorge Cruz-Reyes, Joshua Meehan, Karissa Hughes, Pawan K. Doharey, Shelly Gulati, Vikas Kumar, Mary Grace Martinez, Blaine H. M. Mooers
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 4, p e0211525 (2019)
PLoS ONE, Vol 14, Iss 4, p e0211525 (2019)
Uridylate insertion/deletion RNA editing inTrypanosoma bruceiis a complex system that is not found in humans, so there is interest in targeting this system for drug development. This system uses hundreds of small non-coding guide RNAs (gRNAs) to modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86526f60b24f7c8ab3a3e12703e89126
https://doi.org/10.1101/524702
https://doi.org/10.1101/524702
Publikováno v:
Molecular and Cellular Biology. 22:4652-4660
Trypanosome RNA editing is a unique U insertion and U deletion process that involves cycles of pre-mRNA cleavage, terminal U addition or U removal, and religation. This editing can occur at massive levels and is directed by base pairing of trans-acti
Publikováno v:
The EMBO Journal. 16:4069-4081
Kinetoplastid mitochondrial RNA editing, the insertion and deletion of U residues, is catalyzed by sequential cleavage, U addition or removal, and ligation reactions and is directed by complementary guide RNAs. We have purified a approximately 20S en
Autor:
Alfredo, Hernandez, Bhaskara Reddy, Madina, Kevin, Ro, James A, Wohlschlegel, Belinda, Willard, Mike T, Kinter, Jorge, Cruz-Reyes
Publikováno v:
The Journal of biological chemistry. 285(2)
Regulation of gene expression in kinetoplastid mitochondria is largely post-transcriptional and involves the orchestration of polycistronic RNA processing, 3′-terminal maturation, RNA editing, turnover, and translation; however, these processes rem
Autor:
Kari Halbig, Jorge Cruz-Reyes, Lawrence J. Dangott, Catherine Cifuentes-Rojas, Mónica De Nova-Ocampo, Anastasia Sacharidou, Alfredo J. Hernandez
Trypanosome U insertion and U deletion RNA editing of mitochondrial pre-mRNAs is catalyzed by multisubunit editing complexes as directed by partially complementary guide RNAs. The basic enzymatic activities and protein composition of these high-molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5423b8892d71fda30a4eb07ec3c13418
https://europepmc.org/articles/PMC1484423/
https://europepmc.org/articles/PMC1484423/
Publikováno v:
International journal for parasitology. 36(12)
Mitochondrial gene expression in kinetoplastids is controlled after transcription, potentially at the levels of RNA maturation, stability and translation. Among these processes, RNA editing by U-insertion/deletion catalysed by multi-subunit editing c
Publikováno v:
Nucleic acids research. 26(16)
RNA editing, the processing that generates functional mRNAs in trypanosome mitochondria, involves cycles of protein catalyzed reactions that specifically insert or delete U residues. We recently reported purification from Trypanosoma brucei mitochond