Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ana Paula Sousa"'
Autor:
Sandra Almeida-Reis, Alexandra Carvalho, Conceição Dias, Raquel Brito, Rita Silva, Teresa Almeida-Santos, João Ramalho-Santos, Ana Paula Sousa
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 281 (2024)
Age-related changes in the mitochondrial status of human cumulus cells (hCCs) impact oocyte quality; however, the relationship between hCC mitochondrial (dys)function and reproductive aging remains poorly understood. This study aimed to establish the
Externí odkaz:
https://doaj.org/article/96d528b2141f4513866ae741c3c2da44
Autor:
João Ramalho-Santos, Maria João Soares, Teresa Almeida-Santos, Raquel Fernandes, Ana Paula Sousa, Ana Filipa Ferreira
Publikováno v:
Theriogenology. 157:218-225
Advanced maternal age is an emerging health problem which involves many functional and structural alterations in oocytes, and its study is relevant to design better approaches to improve the reproductive function in women of advanced age. A constrain
Autor:
Renata S, Tavares, Sara, Escada-Rebelo, Maria M, Soares, Andreia F, Silva, Teresa, Almeida-Santos, Sandra, Amaral, Ana Paula, Sousa, João, Ramalho-Santos
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2310
A positive relationship between mitochondrial functionality and gamete quality, ultimately contributing to fertilization success and normal embryo development has been established for some years now. Both mitochondrial membrane potential (MMP) and re
Autor:
Ana Filipa Ferreira, Ana Paula Sousa, Teresa Almeida-Santos, Maria João Soares, Sandra Almeida Reis, João Ramalho-Santos
Publikováno v:
Reproduction (Cambridge, England). 161(3)
Mitochondrial supplementation was proposed as a complementary treatment to assisted reproductive technologies to improve oocyte competence and support post-fertilization development. This strategy is based on the fact that poor-quality/aged oocytes c
Publikováno v:
REPRODUCTION. 147:817-824
We have applied the mitochondria-specific superoxide fluorescent probe MitoSOX Red (MitoSOX) to detect mitochondria-specific reactive oxygen species (mROS) production in human sperm samples using flow cytometry. We show that human ejaculates are hete
Exogenous glucose improves long-standing human sperm motility, viability, and mitochondrial function
Publikováno v:
Fertility and Sterility. 96:848-850
A relevant fraction of human sperm can be maintained in simple phosphate-buffered saline (PBS) for more than 1 week at room temperature, a time that could be doubled if glucose was available. This does not seem to be directly due to sperm mitochondri
Autor:
Pedro Caballero Peregrín, Pedro Caballero Campo, A. Freitas, Teresa Almeida-Santos, Ana Paula Sousa, Renata S. Tavares, João Ramalho-Santos, Marta Baptista, Artur Paiva, Alexandra Amaral
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18112 (2011)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS ONE
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS ONE
Human sperm samples are very heterogeneous and include a low amount of truly functional gametes. Distinct strategies have been developed to characterize and isolate this specific subpopulation. In this study we have used fluorescence microscopy and f
Autor:
Alexandra Amaral, João Ramalho-Santos, Paula Mota, Sandra Amaral, Ana Paula Sousa, Sandra Varum
Publikováno v:
Human reproduction update. 15(5)
Background Mitochondria are multitasking organelles involved in ATP synthesis, reactive oxygen species (ROS) production, calcium signalling and apoptosis; and mitochondrial defects are known to cause physiological dysfunction, including infertility.