Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sushanth Gouni"'
Autor:
Angelique Biancotto, Alexei A. Grom, Yin Liu, Adriana Almeida de Jesus, Alejandro V. Villarino, Bernadette Marrero, Raphaela Goldbach-Mansky, Joseph A. Duncan, Zuoming Deng, Ronald M. Laxer, Yan Huang, Susanne M. Benseler, Sushanth Gouni, Kristien J. M. Zaal, Scott W. Canna, Michael A. DiMattia, Dawn Chapelle, John J. O'Shea, Thomas A. Fleisher, Stephen R. Brooks, Nicole Plass, Hanna Kim, Gina A. Montealegre Sanchez
Publikováno v:
Nature genetics
Inflammasomes are innate immune sensors that respond to pathogen- and damage-associated signals with caspase-1 activation, interleukin (IL)-1β and IL-18 secretion, and macrophage pyroptosis. The discovery that dominant gain-of-function mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64dcae29e96be7611ce685e9650d8f0
Autor:
Susanne M. Benseler, Sushanth Gouni, Bernadette Marrero, G Montealegre, Yan Huang, Stephen R. Brooks, Dawn Chapelle, Nicole Plass, Yin Liu, Ronald M. Laxer, Scott W. Canna, Michael A. DiMattia, Raphaela Goldbach-Mansky, Adriana Almeida de Jesus, Zuoming Deng
Publikováno v:
Arthritis & Rheumatology. 66:S203-S203
Background/Purpose: Macrophage Activation Syndrome (MAS) is a life-threatening systemic inflammatory disorder of unknown etiology. While MAS has no known genetic basis, clinical similarity with a genetic disorder of impaired cytotoxicity known as pri