Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sassi, Celeste"'
Autor:
Sassi, Celeste, Capozzo, Rosa, Hammer, Monia, Zecca, Chiara, Federoff, Monica, Blauwendraat, Cornelis, Bernstein, Nick, Ding, Jinhui, Gibbs, J. Raphael, Price, Timothy, Singleton, Andrew, Logroscino, Giancarlo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Frontotemporal dementia (FTD) refers to a complex spectrum of clinically and genetically heterogeneous disorders. Although fully penetrant mutations in several genes have been identified and can explain the pathogenic mechanisms underlying a great po
Autor:
Blumenau, Sonja, Foddis, Marco, Müller, Susanne, Holtgrewe, Manuel, Bentele, Kajetan, Berchtold, Daniel, Beule, Dieter, Dirnagl, Ulrich, Sassi, Celeste
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Alzheimer’s disease and small vessel ischemic disease frequently co-exist in the aging brain. However, pathogenic links between these 2 disorders are yet to be identified. Therefore we used Taqman genotyping, exome and RNA sequencing to investigate
Autor:
Sassi, Celeste, Nalls, Michael A, Medway, Christopher, Clement, Naomi, Lord, Jenny, Turton, James, Bras, Jose, Almeida, Maria R, Consortium, ARUK, Holstege, Henne, Louwersheimer, Eva, van der Flier, Wiesje M, Ridge, Perry G, Scheltens, Philip, Van Swieten, John C, Santana, Isabel, Oliveira, Catarina, Morgan, Kevin, Powell, John F, Kauwe, John S, Cruchaga, Carlos, Goate, Alison M, Singleton, Andrew B, Gibbs, Jesse R, Guerreiro, Rita, Hardy, John, Passmore, Peter, Craig, David, Johnston, Janet, McGuinness, Bernadette, Todd, Stephen, Heun, Reinhard, Kölsch, Heike, Kehoe, Patrick G, Ding, Jinhui, Vardy, Emma R L C, Hooper, Nigel M, Mann, David M, Pickering-Brown, Stuart, Brown, Kristelle, Lowe, James, Smith, A David, Wilcock, Gordon, Warden, Donald, Lupton, Michelle K, Holmes, Clive, Troakes, Claire, Lunnon, Katie, Al-Sarraj, Safa, Brown, Kristelle S
Publikováno v:
Neurobiology of aging 46, 235.e1-235.e9 (2016). doi:10.1016/j.neurobiolaging.2016.04.004
Sassi, C, Nalls, M A, Ridge, P G, Gibbs, J R, Ding, J, Lupton, M K, Troakes, C, Lunnon, K, Al-Sarraj, S, Brown, K S, Medway, C, Clement, N, Lord, J, Turton, J, Bras, J, Almeida, M R, Holstege, H, Louwersheimer, E, van der Flier, W M, Scheltens, P, Van Swieten, J C, Santana, I, Oliveira, C, Morgan, K, Powell, J F, Kauwe, J S, Cruchaga, C, Goate, A M, Singleton, A B, Guerreiro, R & Hardy, J 2016, ' ABCA7 p.G215S as potential protective factor for Alzheimer's disease ', Neurobiology of Aging, vol. 46, pp. 235.e1–235.e9 . https://doi.org/10.1016/j.neurobiolaging.2016.04.004
Neurobiology of Aging, 46:235.e1. Elsevier Inc.
Neurobiology of Aging, 46. Elsevier Inc.
Neurobiology of Aging
Sassi, C, Nalls, M A, Ridge, P G, Gibbs, J R, Ding, J, Lupton, M K, Troakes, C, Lunnon, K, Al-Sarraj, S, Brown, K S, Medway, C, Clement, N, Lord, J, Turton, J, Bras, J, Almeida, M R, Holstege, H, Louwersheimer, E, van der Flier, W M, Scheltens, P, Van Swieten, J C, Santana, I, Oliveira, C, Morgan, K, Powell, J F, Kauwe, J S, Cruchaga, C, Goate, A M, Singleton, A B, Guerreiro, R & Hardy, J 2016, ' ABCA7 p.G215S as potential protective factor for Alzheimer's disease ', Neurobiology of Aging, vol. 46, pp. 235.e1–235.e9 . https://doi.org/10.1016/j.neurobiolaging.2016.04.004
Neurobiology of Aging, 46:235.e1. Elsevier Inc.
Neurobiology of Aging, 46. Elsevier Inc.
Neurobiology of Aging
Genome-wide association studies (GWASs) have been effective approaches to dissect common genetic variability underlying complex diseases in a systematic and unbiased way. Recently, GWASs have led to the discovery of over 20 susceptibility loci for Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8d8d19d810017eb1826c5a013735a96c
Autor:
Sassi, Celeste, Guerreiro, Rita, Gibbs, Raphael, Ding, Jinhui, Lupton, Michelle K., Troakes, Claire, Al-Sarraj, Safa, Niblock, Michael, Gallo, Jean-Marc, Adnan, Jihad, Killick, Richard, Brown, Kristelle S., Medway, Christopher, Lord, Jenny, Turton, James, Bras, Jose, Morgan, Kevin, Powell, John F., Singleton, Andrew, Hardy, John
Publikováno v:
Neurobiology of Aging
Sassi, C, Guerreiro, R, Gibbs, R, Ding, J, Lupton, M K, Troakes, C, Al-Sarraj, S, Niblock, M, Gallo, J M, Adnan, J, Killick, R, Brown, K S, Medway, C, Lord, J, Turton, J, Bras, J, Morgan, K, Powell, J F, Singleton, A & Hardy, J 2014, ' Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease ', Neurobiology of Aging, vol. 35, no. 12, pp. 2881.e1-2881.e6 . https://doi.org/10.1016/j.neurobiolaging.2014.06.002
Sassi, C, Guerreiro, R, Gibbs, R, Ding, J, Lupton, M K, Troakes, C, Al-Sarraj, S, Niblock, M, Gallo, J M, Adnan, J, Killick, R, Brown, K S, Medway, C, Lord, J, Turton, J, Bras, J, Morgan, K, Powell, J F, Singleton, A & Hardy, J 2014, ' Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease ', Neurobiology of Aging, vol. 35, no. 12, pp. 2881.e1-2881.e6 . https://doi.org/10.1016/j.neurobiolaging.2014.06.002
The overlapping clinical and neuropathologic features between late-onset apparently sporadic Alzheimer's disease (LOAD), familial Alzheimer's disease (FAD), and other neurodegenerative dementias (frontotemporal dementia, corticobasal degeneration, pr