Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Samuel K. Handelman"'
Autor:
Allison L. Kuipers, Michele K. Evans, Liubov Arbeeva, Ching-Ti Liu, Tamara B. Harris, Michelle S. Yau, Aude Nicolas, Salman M. Tajuddin, Joanne M. Jordan, Struan F.A. Grant, Ryan Price, Rebecca D. Jackson, Douglas P. Kiel, Babette S. Zemel, Samuel K. Handelman, Yi-Hsiang Hsu, David Karasik, Joseph M. Zmuda, Alessandra Chesi
Publikováno v:
J Bone Miner Res
Genetic studies of bone mineral density (BMD) largely have been conducted in European populations. We therefore conducted a meta-analysis of six independent African ancestry cohorts to determine whether previously reported BMD loci identified in Euro
Autor:
Lillias H. Maguire, Yanhua Chen, Tune H. Pers, Elizabeth K. Speliotes, Samuel K. Handelman, Xiaomeng Du
Publikováno v:
Nature genetics
Diverticular disease is common and has a high morbidity. Treatments are limited owing to the poor understanding of its pathophysiology. Here, to elucidate its etiology, we performed a genome-wide association study of diverticular disease (27,444 case
Autor:
Elizabeth K. Speliotes, Yue Chen, James G. Terry, Adolfo Correa, Bratati Kahali, Yii-Der Ida Chen, Vilmundur Gudnason, Yanhua Chen, Jeffrey R. O'Connell, Brian D. Halligan, Tamara B. Harris, Matthew A. Allison, Thomas H. Mosley, Xiuqing Guo, Matthew J. Budoff, Donald W. Bowden, J. Jeffrey Carr, Lenore J. Launer, Sharon L.R. Kardia, Kathleen A. Ryan, Jian Yang, Xiaomeng Du, Samuel K. Handelman, Breland F. Crudup, Laura M. Yerges-Armstrong, Lawrence F. Bielak, Yash Hegde, Shannon Carskadon, Ariella Cohain, Nicholette D. Palmer, Gudny Eiriksdottir, Solomon K. Musani, Eric E. Schadt, Nallasivam Palanisamy, Lynne E. Wagenknecht, Michael A. Province, Yi-Ping Fu, Christopher J. O'Donnell, Patricia A. Peyser, Albert V. Smith, Mary F. Feitosa, Jerome I. Rotter, Jiankang Liu, Andrew Bakshi, Lindsay Stetson, Jill M. Norris
Publikováno v:
J Clin Endocrinol Metab
Context Glycogen storage diseases are rare. Increased glycogen in the liver results in increased attenuation. Objective Investigate the association and function of a noncoding region associated with liver attenuation but not histologic nonalcoholic f
Autor:
Jean Wactawski-Wende, Carolyn J. Crandall, Youjin Wang, Kathleen M. Hovey, Lara E. Sucheston-Campbell, Jing Nie, Leah Preus, Rebecca D. Jackson, Samuel K. Handelman, Heather M. Ochs-Balcom, Rami Nassir
Publikováno v:
The American Journal of Clinical Nutrition. 105:970-979
Background: Fracture is a complex trait, affected by both genetic and environmental factors. A meta-analysis of genome-wide association studies (GWASs) identified multiple bone mineral density (BMD) and fracture-associated loci.Objective: We conducte
Autor:
Philip M. Brown, Olga V. Belyaeva, Cara Nestlerode, Natalia Y. Kedishvili, Katherine Valles, Yaron Rotman, Arun J. Sanyal, Yanhua Chen, Emmanuel Thomas, Yanling Ma, Vincent L. Chen, Ynto S. de Boer, Elizabeth K. Speliotes, Suman Karki, Joseph M. Zmuda, Christopher Koh, Xiaomeng Du, Koji Fujita, Samuel K. Handelman, David E. Kleiner, T. Jake Liang
Publikováno v:
Hepatology (Baltimore, Md.). 69(4)
Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease. A single nucleotide polymorphism (SNPs), rs6834314, was associated with serum liver enzymes in the general population, presumably reflecting liver fat or injury. We
Autor:
Rebecca D. Jackson, Jing Nie, Rami Nassir, Leah Preus, Kathleen M. Hovey, Lara E. Sucheston-Campbell, Youjin Wang, Samuel K. Handelman, Heather M. Ochs-Balcom, Jean Wactawski-Wende, Carolyn J. Crandall
Publikováno v:
The Journal of clinical endocrinology and metabolism. 102(6)
Context Evidence supports a protective effect of menopausal hormone therapy (HT) on bone. However, whether genetic susceptibility modifies the association of HT and fracture risk is not sufficiently explored. Objective The objective was to test an in
Autor:
Michal Seweryn, Adam Brandemihl, Christopher Holloman, Henrik Källberg, Tom Kristian Grimsrud, Brett Burkholder, Randall E. Harris, Tom Børge Johannesen, Samuel K. Handelman, Ruo Pan Huang, Maria Feychting, Anders Ahlbom, Grzegorz A. Rempala, Judith A. Schwartzbaum
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137503 (2015)
PLoS ONE
PLoS ONE
Allergy is inversely related to glioma risk. To determine whether prediagnostic allergy-related serum proteins are associated with glioma, we conducted a nested case-control study of seven cytokines (IL4, IL13, IL5, IL6, IL10, IFNG, TGFB2), two solub
Autor:
Adam Suhy, Wolfgang Sadee, Amy Webb, John Oberdick, Roshan Mascarenhas, Samuel K. Handelman, Ryan M. Smith, Leslie C. Newman, Audrey C. Papp
Publikováno v:
BMC Genomics
Background Measuring allelic RNA expression ratios is a powerful approach for detecting cis-acting regulatory variants, RNA editing, loss of heterozygosity in cancer, copy number variation, and allele-specific epigenetic gene silencing. Whole transcr