Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nick Maisey"'
Autor:
J Zylstra, Nick Maisey, Cara R. Baker, Daniel M. Foley, Jesper Lagergren, Mohamed Saad Aboul-Enein, William R. C. Knight, Elizabeth C Smyth, Mark Kelly, Andrew Davies, James A. Gossage, David Cunningham, Wahyu Wulaningsih, Dionysios Dellaportas, William H. Allum
Publikováno v:
Journal of Surgical Oncology. 124:1296-1305
BACKGROUND Most patients presenting with oesophageal cancer do so with advanced disease not suitable for surgery. However, there are examples of encouraging survival following surgery in highly selected patients who respond well to chemotherapy. METH
Autor:
Robert Carroll, Christopher Kiff, Dara Stein, David Tyas, Delphine Saragoussi, Mira Soni, Ayman Nassar, Nick Maisey
Publikováno v:
Future oncology (London, England). 17(24)
Lay abstract This study looked at the characteristics and quality of life (QoL) of patients who were taking the drug, nivolumab, and how well it works for advanced gastric/gastroesophageal junction (GEJ) adenocarcinoma. GEJ adenocarcinoma is a rare t
Autor:
William R. C. Knight, A. E. T. Jacques, Nick Maisey, Orla Hynes, S. George, Connie Yip, Nyree Griffin, Mark L. Green, CM Iezzi, Cara R. Baker, A. Qureshi, B. Gill‐Barman, Sebastian Zeki, David Landau, Andrew Gaya, Wahyu Wulaningsih, Ula Mahadeva, Jason M Dunn, Jesper Lagergren, S. Ngan, J Zylstra, G. Tham, Mark Kelly, James A. Gossage, Vicky Goh, J. Meenan, Fuju Chang, M. Van Hemelrijck, H. Deere, Andrew Davies
Publikováno v:
BJS Open
BJS Open, Vol 3, Iss 6, Pp 767-776 (2019)
BJS Open, Vol 3, Iss 6, Pp 767-776 (2019)
Background A positive circumferential resection margin (CRM) has been associated with higher rates of locoregional recurrence and worse survival in oesophageal cancer. The aim of this study was to establish if clinicopathological and radiological var
Autor:
Nick Maisey, Elisa Fontana, Nicola Valeri, Andrea Lampis, Elizabeth C Smyth, S.J. Lin, Matteo Fassan, Andrew Davies, Jesper Lagergren, William H. Allum, G. Nyamundanda, Jens C. Hahne, Anguraj Sadanandam, C. Ragulan, Ruth E Langley, J Zylstra, Matthew Nankivell, James A. Gossage, I.B. Tan, David Cunningham, Patrick Tan, A C Wotherspoon, Mark L. Green
Background Following neoadjuvant chemotherapy for operable gastroesophageal cancer, lymph node metastasis is the only validated prognostic variable; however, within lymph node groups there is still heterogeneity with risk of relapse. We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b50625fe0e547af23f43597833725b4
http://hdl.handle.net/11577/3291023
http://hdl.handle.net/11577/3291023
Publikováno v:
Diseases of the Esophagus. 31
Previous researchers have focused upon the influence of postoperative complications upon prognosis from esophagectomy, with very little attention paid to the potential negative effects of complications during neoadjuvant therapy. The hypothesis under
Autor:
Nick Maisey, James A. Gossage, Elizabeth C Smyth, Andrew Davies, Fredrik Mattsson, David Cunningham, William H. Allum, J Zylstra, Jesper Lagergren, Robert Mason
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 32(27)
Purpose Neoadjuvant chemotherapy is established in the management of most resectable esophageal and esophagogastric junction adenocarcinomas. However, assessing the downstaging effects of chemotherapy and predicting response to treatment remain chall
Autor:
Nyree Griffin, Andrew Gaya, Orla Hynes, Gary Cook, Connie Yip, James A. Gossage, Robert Mason, Rosalind Mitchell-Hay, Andrew Davies, David Landau, Nick Maisey, Paul Ross, Vicky Goh
Publikováno v:
European radiology. 24(5)
Sarcopenia and changes in body composition following neoadjuvant chemotherapy (NAC) may affect clinical outcome. We assessed the associations between CT body composition changes following NAC and outcomes in oesophageal cancer.A total of 35 patients
Autor:
Ian Chau, Stephen J. Gwyther, Helen Marshall, Tim Maughan, John Wagstaff, Mark A. Hill, Jonathan Wadsley, Alfred Oliver, Catherine Lowe, Gary Middleton, S. Myint, Vicky Napp, Sarah Brown, Denise Blake, Simon Gollins, Sarah Slater, Matthew T. Seymour, Susan D. Richman, John Bridgewater, Nick Maisey
Publikováno v:
European Journal of Cancer. 49(16)
Background: The main toxicity of irinotecan in advanced colorectal cancer (CRC) is delayed diarrhoea. Intestinal SN-38, released by deconjugation of the parent glucuronide excreted into the bile or produced in situ by intestinal carboxylesterase, is
Autor:
Kim Benstead, Stephen Falk, Nick Maisey, Ian Chau, Ann O'Callaghan, Tim Maughan, Helen Marshall, Gary Middleton, Mark A. Hill, Susan D. Richman, Sarah Brown, Jennifer F Seligmann, Phil Quirke, Philip A. Chambers, Jonathan Wadsley, Vicky Napp, Matthew T. Seymour, Lesley Dawson, Catherine Lowe, Stephen J. Gwyther, Alfred Oliver
Publikováno v:
The Lancet Oncology. 14(8)
Background: Therapeutic antibodies targeting EGFR have activity in advanced colorectal cancer, but results from clinical trials are inconsistent and the population in which most benefit is derived is uncertain. Our aim was to assess the addition of p
Autor:
Cathryn M. Lewis, M. Arenas Hernandez, Nick Maisey, Anthony M. Marinaki, Peter Harper, Jeremy D. Sanderson, Lynette D. Fairbanks, Aathavan Loganayagam, Paul Ross, A. Corrigan
Publikováno v:
British Journal of Cancer
Background: Fluoropyrimidine drugs are extensively used for the treatment of solid cancers. However, adverse drug reactions are a major clinical problem, often necessitating treatment discontinuation. The aim of this study was to identify pharmacogen