Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Angelo M. De Marzo"'
Autor:
Susan L. Dalrymple, Yezi Zhu, Peter S. Nelson, Jun Luo, Jianfeng Xu, Alan K. Meeker, Samuel R. Denmeade, Emmanuel S. Antonarakis, S. Lilly Zheng, William B. Isaacs, Angelo M. De Marzo, Jody E. Hooper, Ilsa Coleman, John T. Isaacs, W. Nathaniel Brennen
Publikováno v:
Oncogene
The role of truncated androgen receptor splice variant-7 (AR-V7) in prostate cancer biology is an unresolved question. Is it simply a marker of resistance to 2nd-generation androgen receptor signaling inhibitors (ARSi) like abiraterone acetate (Abi)
Autor:
David Lim, Mindy K. Graham, Eva Corey, Tamara L. Lotan, Jonathan I. Epstein, Alan K. Meeker, Christopher M. Heaphy, Hao Wang, Mario A. Eisenberger, Angelo M. De Marzo, Christine Davis, Michael C. Haffner
Publikováno v:
Hum Pathol
BACKGROUND: Small cell neuroendocrine carcinoma (SCNC) of the prostate is an aggressive subtype with frequent TP53 mutation and RB1 inactivation, however the molecular phenotype remains an area of investigation. Here, we compared telomere lengths in
Autor:
Ibrahim Kulac, Heidi Hempel Sullivan, Nathan Cuka, John R. Barber, Christopher M. Heaphy, Angelo M. De Marzo, Jiayun Lu, Tamara L. Lotan, Corinne E. Joshu, Karen S. Sfanos
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:668-675
Background: Given our previous findings that low intratumoral and high extratumoral mast cell numbers are associated with higher risk of biochemical recurrence after radical prostatectomy, we now assessed this relationship with race and the developme
Autor:
Angelo M. De Marzo, Jeffrey J. Tosoian, Tamara L. Lotan, Ashley E. Ross, Mufaddal Mamawala, Liana B. Guedes, H. Ballentine Carter, Bruce J. Trock, Misop Han, Carlos L. Morais
Publikováno v:
Prostate cancer and prostatic diseases
Background: Up to half of men with Gleason score 6 (GS6) prostate cancers initially managed with active surveillance (AS) will eventually require definitive therapy, usually due to tumor grade reclassification during follow-up. We examined the associ
Autor:
Jiayun Lu, Tamara L. Lotan, Logan Reitz, Harsimar B. Kaur, Jeffrey J. Tosoian, Angelo M. De Marzo, John R. Barber, Scott A. Tomlins, Karen S. Sfanos, Corinne E. Joshu, Edward M. Schaeffer, Liana B. Guedes, Laneisha Maldonado
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
The inflammatory microenvironment plays an important role in the pathogenesis and progression of tumors and may be associated with somatic genomic alterations. We examined the association of tumor-infiltrating T-cell density with clinical-pathologic
Autor:
Angelo M. De Marzo, Misop Han, Elizabeth B. Humphreys, Fawaz Almutairi, Ashley E. Ross, Jessica Hicks, Stephanie Glavaris, Edward M. Schaeffer, Tamara L. Lotan, Debasish Sundi, Carlos L. Morais, Jeffrey J. Tosoian, Bruce J. Trock, Scott A. Tomlins
Publikováno v:
European Urology. 71:697-700
African-American (AA) men have a higher risk of lethal prostate cancer (PCa) compared to European-American (EA) men. However, the molecular basis of this difference, if any, remains unclear. In EA PCa, PTEN loss, but not ERG rearrangement, has been a
Autor:
Jeffrey J. Tosoian, Dorhyun Johng, Tamara L. Lotan, Miao Zhang, Charles M. Ewing, Sarah D. Isaacs, Helen Fedor, Alba Torres, Angelo M. De Marzo, Liana B. Guedes, Jessica Hicks, William B. Isaacs
Publikováno v:
Oncotarget
// Tamara L. Lotan 1, 2 , Alba Torres 1 , Miao Zhang 3 , Jeffrey J. Tosoian 4 , Liana B. Guedes 1 , Helen Fedor 1 , Jessica Hicks 1 , Charles M. Ewing 4 , Sarah D. Isaacs 4 , Dorhyun Johng 4 , Angelo M. De Marzo 1, 2, 4 , William B. Isaacs 2, 4 1 Dep
Autor:
Angelo M. De Marzo, Tamara L. Lotan, Jessica Hicks, Carlos L. Morais, Alexander S. Baras, Liana B. Guedes
Publikováno v:
Human Pathology. 55:117-125
High-grade prostatic intraepithelial neoplasia (HGPIN) is widely believed to represent a precursor to invasive prostatic adenocarcinoma. However, recent molecular studies have suggested that retrograde spread of invasive adenocarcinoma into pre-exist
Autor:
Jessica L. Hicks, Sarah L. Poynton, Karen S. Sfanos, Angelo M. De Marzo, Lauren B. Peiffer, Sarah E. Ernst
Publikováno v:
The Prostate. 79(11)
Background Urogenital infection with Schistosoma haematobium is a risk factor for the development of squamous cell carcinoma of the urinary bladder. The pathophysiology is thought to be mediated in part by inflammation, cellular damage, and bladder r
Autor:
Francesca Khani, Jonathan I. Epstein, Colin C. Pritchard, Jessica L. Hicks, Christopher E. Barbieri, Angelo M. De Marzo, Tamara L. Lotan, Sara E. Wobker, Brian D. Robinson
Publikováno v:
The Journal of pathologyReferences. 249(1)
Intraductal carcinoma of the prostate (IDC-P) most often appears associated with high-grade invasive prostate carcinoma (PCa), where it is believed to represent retrograde spread. However, IDC-P rarely occurs as an isolated finding at radical prostat