Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chien Hsing Lin"'
Autor:
Shih-Ching Chang, Anna Fen-Yau Li, Pei-Ching Lin, Chun-Chi Lin, Hung-Hsin Lin, Shen-Chieh Huang, Chien-Hsing Lin, Wen-Yi Liang, Wei-Shone Chen, Jeng-Kai Jiang, Jen-Kou Lin, Shung-Haur Yang, Yuan-Tzu Lan
Publikováno v:
Cancers, Vol 12, Iss 11, p 3487 (2020)
Background: The 5’-C-phosphate-G-3’ island methylator phenotype (CIMP) is a specific phenotype of colorectal cancer (CRC) associated with microsatellite instability-high (MSI-high) tumors. Methods: In this study, we determined the CIMP status usi
Externí odkaz:
https://doaj.org/article/f502b4a68bc34afa846babb446b1f8db
Autor:
Yee Chao, Shung Haur Yang, Chien Hsing Lin, Yuan Tzu Lan, Wen Yi Liang, Jiun I. Lai, Hung Hsin Lin, Pei Ching Lin, Meng Lun Lu, Shih Ching Chang, Ming Huang Chen, Chun Chi Lin, Muh Hwa Yang
Publikováno v:
The Oncologist. 24:1534-1542
Background The form of microsatellite instability (MSI) affecting tetranucleotide repeats known as elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) has emerged as a new potential biomarker in multiple cancers. In colore
Autor:
Wen Yi Liang, Shung Haur Yang, Pei Ching Lin, Chien Hsing Lin, Wei Shone Chen, Yuan Tzu Lan, Jeng Kai Jiang, Shih Ching Chang, Jen Kou Lin
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 9, Iss 2, Pp 476-486 (2020)
Cancer Medicine, Vol 9, Iss 2, Pp 476-486 (2020)
Background We assumed that targeted next‐generation sequencing (NGS) of mismatch repair‐associated genes could improve the detection of driving mutations in colorectal cancers (CRC) with microsatellite instability (MSI) and microsatellite alterat
Autor:
Wen-Yiah Liang, Ming Huang Chen, Yuan-Tzu Lan, Chun Chi Lin, Jen-Kou Lin, Jeng-Kai Jiang, Shung Haur Yang, Wei-Shone Chen, Shih-Ching Chang, Chien-Hsing Lin
Publikováno v:
Journal of Clinical Oncology. 36:e15591-e15591
e15591Background: Elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) is another form of microsatellite instability (MSI) at tetranucleotide repeats and has emerged as a...
Autor:
Jeng Kai Jiang, Jen Kou Lin, Shih Ching Chang, Shung Haur Yang, Wei Shone Chen, Pei Ching Lin, Chien Hsing Lin, Wen Yi Liang
Publikováno v:
Annals of surgical oncology. 23(3)
Colorectal cancer (CRC) is a heterogeneous disease caused by genetic and epigenetic alterations. This study aimed to describe the mutation frequency of 12 genes in different CRC phenotypes.Patients who underwent surgery at the Taipei Veterans General
Mutations in the RAS and PI3K pathways are associated with metastatic location in colorectal cancers
Autor:
Yuan-Tzu, Lan, Lin, Jen-Kou, Chien-Hsing, Lin, Shung-Haur, Yang, Chun-Chi, Lin, Huann-Sheng, Wang, Wei-Shone, Chen, Tzu-Chen, Lin, Jeng-Kai, Jiang, Shih-Ching, Chang
Publikováno v:
Journal of surgical oncology. 111(7)
Identification of mutations in the downstream epidermal growth factor receptor (EGFR) signaling pathway could provide important insights of EGFR-targeted therapies in colorectal cancers. We analyzed the mutation spectra of the PI3K/PTEN/AKT and RAS/R
Autor:
Jen Kou Lin, Chih Chi Chou, Shung Haur Yang, Hung Hsin Lin, Chien Hsing Lin, Jeng Kai Jiang, Shih Ching Chang, Shih-Feng Tsai, Pei Ching Lin, Wei Shone Chen
Publikováno v:
Annals of surgical oncology. 22
DNA methylation is a potential tumor marker for several cancers, including colorectal cancer (CRC), because of its heritable and stable characteristics. Using a high-resolution, genome-wide approach, we epigenotyped >450,000 CpG sites in tumor and ad
Autor:
Wei Shone Chen, Ya Hui Chang, Jin Hwang Liu, Hwey May Chang, Jen Kou Lin, Yuan-Tsong Chen, Chien Hsing Lin, Shih-Feng Tsai, Ling-Hui Li, Shih Ching Chang
Publikováno v:
Journal of Biomedical Science, Vol 18, Iss 1, p 36 (2011)
Journal of Biomedical Science
Journal of Biomedical Science
Background Colorectal cancer (CRC) is a major health concern worldwide, and recently becomes the most common cancer in Asia. The case collection of this study is one of the largest sets of CRC in Asia, and serves as representative data for investigat