Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Weihui Zhang"'
Publikováno v:
Molecular Medicine Reports
Acute pancreatitis (AP) is a common digestive disorder with high morbidity and mortality. The present study aimed to investigate the expression of early growth response protein 1 (Egr1), and the effect of competing endogenous (ce)RNA network on tryps
Publikováno v:
Pancreatology. 17:237-246
With the deepening of research, the roles of LncRNAs play in the fibrotic process have attracted great attention. At the early stage of pancreatic fibrogenesis, to effectively regulate pancreatic stellate cells (PSCs) activation is crucial for the tr
Autor:
Weihui Zhang, Zhituo Li, Haijun Sun, Jiangtao Chu, Biao Ma, Dali Zhao, Dongbo Xue, Xueming Zhang
Publikováno v:
Acta biochimica et biophysica Sinica. 52(2)
The aim of this study was to investigate the role and mechanism of miR-155 in regulating autophagy in a caerulein-induced acute pancreatitis (AP) cellular model. GFP-LC3 immunofluorescence assay was performed to detect autophagy vesicle formation in
Autor:
Zhituo Li, Dali Zhao, Weihui Zhang, Yang Huang, Dongbo Xue, Bo Gao, Biao Ma, Yong Zhang, Xueming Zhang
Publikováno v:
Molecular Medicine Reports
Acute pancreatitis (AP) exhibits high morbidity and mortality rates. The onset of AP is characterized by early trypsinogen activation. The present study aimed to investigate the expression of microRNA (miR)-92a-3p and early growth response protein 1
Publikováno v:
Molecular Medicine Reports. 14:590-598
Acute pancreatitis (AP) is a common acute digestive tract disease, with increased morbidity and mortality, and an unclear pathogenesis. Trypsinogen activation in pancreatic acinar cells may be the primary mechanism underlying the development of AP. P
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Mediators of Inflammation
Mediators of Inflammation
Macrophage activation plays an important role in the inflammatory response in acute pancreatitis. In the present study, the activation of AR42J pancreatic acinar cells was induced by taurolithocholate treatment. The results showed that the culture me
Autor:
Weihui Zhang, Zu-Hua Gao, Yuguo Zhang, Bo Gao, Zhengpeng Yang, Xueming Zhang, Dongbo Xue, Yongming Huang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 3, p e0174142 (2017)
PLoS ONE, Vol 12, Iss 3, p e0174142 (2017)
Liver cirrhosis is recognized as being the consequence of immune-mediated hepatocyte damage and repair processes. However, the regulation of these immune responses underlying liver cirrhosis has not been elucidated. In this study, we used GEO dataset
Publikováno v:
Molecular medicine reports. 16(5)
The present study aimed to screen for differentially expressed extracellular microRNAs (miRNAs) during the development of acute pancreatitis (AP) and validate the miRNA expression in the plasma of patients with AP. The culture medium of taurolithocho
Autor:
Bo Gao, Yuguo Zhang, Weihui Zhang, Tian Yu, Hani Choudhry, Boshi Sun, Jiannis Ragoussis, Dongbo Xue, Zu-Hua Gao, Qin Shao, Victoria Marcus
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178760 (2017)
PLoS ONE
PLoS ONE
Approximately 9% of cancer-related deaths are caused by colorectal cancer. Liver metastasis is a major factor for the high colorectal cancer mortality rate. However, the molecular mechanism underlying colorectal cancer liver metastasis remains unclea
Publikováno v:
Clinics and research in hepatology and gastroenterology. 38(4)
Summary Background and objective As important components of bone marrow microenvironment, bone marrow endothelial cells (BMECs) have important roles in regulating haematopoietic functions of the bone marrow. In preliminary study, we found the humoral