Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Victoria J. Findlay"'
Autor:
E. Ramsay Camp, Cindy Wang, Katie E. Hurst, Victoria J. Findlay, Scott A. Becker, Yun Zhu, Lourdes M. Nogueira
Publikováno v:
Molecular Therapy. 26:744-754
Epithelial-to-mesenchymal transition (EMT) has been closely linked with therapy resistance and cancer stem cells (CSCs). However, EMT pathways have proven challenging to therapeutically target. MicroRNA 145 (miR-145) targets multiple stem cell transc
Publikováno v:
Adv Cancer Res
Breast cancer is a worldwide health issue as it represents the leading cause of cancer in women and the second-leading cause of cancer-related mortality in women, with an increasing incidence. Nothing speaks more clearly to the shocking breast cancer
Publikováno v:
Cancer gene therapy
Although mortality from colorectal cancer (CRC) is decreasing, colorectal cancer is still the second highest cause of cancer related deaths in America. Chemotherapy and radiation therapy now play central roles in our strategies to fight cancer, altho
Autor:
Victoria J. Findlay, Keith L. Kirkwood, Michael Defee, Chris Parsons, Lu Dai, Bryan P. Toole, Dennis K. Watson, Zhiqiang Qin, Jennifer E. Cameron, Francesca Peruzzi
Publikováno v:
Journal of Virology. 87:621-635
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS), and KSHV activation of mitogen-activated protein kinases (MAPKs) initiates a number of key pathogenic determinants of KS. Direct inhibition of signal tran
Autor:
Omar Moussa, Victoria J. Findlay, Victor I. Semenchenko, Mohamed M. Desouki, Dennis K. Watson, Patricia M. Watson, David P. Turner, Amanda C. LaRue, Mostafa Fraig
Publikováno v:
The Prostate. 71:1723-1735
BACKGROUND Ets is a large family of transcriptional regulators with functions in most biological processes. While the Ets family gene, prostate-derived epithelial factor (PDEF), is expressed in epithelial tissues, PDEF protein expression has been fou
Publikováno v:
Cancer Research. 68:8499-8506
Prostate-derived Ets factor (PDEF) is an ETS transcription factor expressed in normal tissues with high epithelial cell content and noninvasive breast cancer cells. A putative tumor suppressor PDEF protein expression is often lost during progression
Autor:
Cindy Wang, Stephen P. Ethier, E. Ramsay Camp, Katie E. Hurst, Victoria J. Findlay, Lourdes M. Nogueira, Daniel Quirk, Dennis K. Watson, Kevin F. Staveley O'Carroll
Epithelial-to-mesenchymal transition (EMT) has been associated with poor treatment outcomes in various malignancies and is inversely associated with miRNA145 expression. Therefore, we hypothesized that SNAI2 (Slug) may mediate 5-fluorouracil (5FU) ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ae338c59653fd63234d5dd6861826a
https://europepmc.org/articles/PMC4221636/
https://europepmc.org/articles/PMC4221636/
Publikováno v:
Adv Cancer Res
Ets factors are members of one of the largest families of evolutionarily conserved transcription factors, regulating critical functions in normal cell homeostasis, which when perturbed contribute to tumor progression. The well-documented alterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb185a0d2cd7bcceee263a753dbdfc39
https://europepmc.org/articles/PMC9677344/
https://europepmc.org/articles/PMC9677344/
Autor:
David P. Turner, Lourdes M. Nogueira, Jamie N. Mills, Qi J Guo, Amanda C. LaRue, Savannah G. Bandurraga, Natalie J Mason, E. Ramsay Camp, Victoria J. Findlay
Publikováno v:
Breast Cancer Research : BCR
Introduction MicroRNAs are small non-coding RNAs that are involved in the post-transcriptional negative regulation of mRNAs. MicroRNA 510 (miR-510) was initially shown to have a potential oncogenic role in breast cancer by the observation of its elev