Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Wei-Lun Hwang"'
Publikováno v:
Cancers, Vol 13, Iss 7, p 1742 (2021)
Head and neck squamous cell carcinomas (HNSCCs) are epithelial malignancies with 5-year overall survival rates of approximately 40–50%. Emerging evidence indicates that a small population of cells in HNSCC patients, named cancer stem cells (CSCs),
Externí odkaz:
https://doaj.org/article/025ecc3fb49e40f090ef6d6cbc4daa1e
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1742, p 1742 (2021)
Cancers, Vol 13, Iss 1742, p 1742 (2021)
Simple Summary Head and neck squamous cell carcinomas (HNSCCs) are highly heterogeneous human malignancies associated with genetic and environmental factors. In HNSCCs, cancer stem cells (CSCs) provide the plasticity for cancer cell progression, meta
Autor:
Ko Hsun Liao, Ting Fen Tsai, Pei Ning Wang, Mel Campbell, Wei Lun Hwang, Wan Shan Yang, Hsing Jien Kung, Fang Shin Nian, Liang Kung Chen, Pei Ching Chang, Ming Wei Lin, Jin Wu Tsai, Chia Pei Yang, Chuan Chuan Chao, Tsai Yu Tzeng, Yuan Chi Teng, Yu Hui Wong, Kai Hsuan Wang, Ming Hsuan Chang
Publikováno v:
Aging Cell
In mammals, microRNAs can be actively secreted from cells to blood. miR‐29b‐3p has been shown to play a pivotal role in muscle atrophy, but its role in intercellular communication is largely unknown. Here, we showed that miR‐29b‐3p was upregu
Autor:
Chih Yung Yang, Yin Quan Chen, Jeng Kai Jiang, Chun Chi Lin, Chih Chan Lee, Hsin Yi Lan, Wei-Chung Cheng, Ruey Hwa Lu, Tzu Yu Yeh, Tsai Tsen Liao, Arthur Er Terg Chiou, Hung Hsin Lin, Shu Han Su, Wei Lun Hwang
Publikováno v:
Cancers, Vol 13, Iss 1833, p 1833 (2021)
Cancers
Volume 13
Issue 8
Cancers
Volume 13
Issue 8
Simple Summary Metastasis of tumor cells is the leading cause of death in cancer patients. Concurrent therapy with surgical removal of primary and metastatic lesions is the main approach for cancer therapy. Currently, therapeutic resistant properties
Autor:
Hsin Yi Lan, Chih Yung Yang, Hung Hsin Lin, Shung Haur Yang, Shih Ching Huang, Wei Lun Hwang, Hsin Chuan Chang, Chi Hung Lin, Muh Hwa Yang, Hao Wei Teng, Jeng Kai Jiang, Wei-Chung Cheng, Lan Ting Emily Yuan, Chun Chi Lin, Tsai Tsen Liao
Publikováno v:
International journal of cancerReferences. 145(8)
The dynamic cell-cell communication is essential for tissue homeostasis in normal physiological circumstances and contributes to a diversified tumor microenvironment. Although exosomes are extracellular vesicles that actively participate in cell-cell
Autor:
Wei Lun Hwang, Shyh Kuan Tai, Tsai Tsen Liao, Muh Hwa Yang, Wen Hao Hsu, Ting Lo, Hsin Yi Lan, Cheng-Chi Chang, Chien Hsin Ho
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 520-533 (2016)
SummaryLet-7 is crucial for both stem cell differentiation and tumor suppression. Here, we demonstrate a chromatin-dependent mechanism of let-7 in regulating target gene expression in cancer cells. Let-7 directly represses the expression of AT-rich i
Autor:
Hsei-Wei Wang, Tse Shun Huang, Hao Wei Teng, Hsin Yi Lan, Chi Hung Lin, Ya-Ping Tsai, Muh Hwa Yang, Chih Yung Yang, Wei Lun Hwang, Shung Haur Yang, Jeng Kae Jiang
Publikováno v:
Nature cell biology. 16(3)
Asymmetrical cell division (ACD) maintains the proper number of stem cells to ensure self-renewal. In cancer cells, the deregulation of ACD disrupts the homeostasis of the stem cell pool and promotes tumour growth. However, this mechanism is unclear.