Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Stephen S Whitehead"'
Autor:
Angkana T. Huang, Henrik Salje, Ana Coello Escoto, Nayeem Chowdhury, Christian Chávez, Bernardo Garcia-Carreras, Wiriya Rutvisuttinunt, Irina Maljkovic Berry, Gregory D. Gromowski, Lin Wang, Chonticha Klungthong, Butsaya Thaisomboonsuk, Ananda Nisalak, Luke M. Trimmer-Smith, Isabel Rodriguez-Barraquer, Damon W. Ellison, Anthony R. Jones, Stefan Fernandez, Stephen J. Thomas, Derek J. Smith, Richard Jarman, Stephen S. Whitehead, Derek A. T. Cummings, Leah C. Katzelnick
Publikováno v:
PLoS Pathogens
PLoS pathogens, vol 18, iss 5
PLoS pathogens, vol 18, iss 5
Funder: Division of Intramural Research, National Institute of Allergy and Infectious Diseases
Funder: Military Infectious Disease Research Program
Funder: Armed Forces Health Surveillance Branch
Neutralizing antibodies are important c
Funder: Military Infectious Disease Research Program
Funder: Armed Forces Health Surveillance Branch
Neutralizing antibodies are important c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968b53759cae40558f62f49e4fa69276
Autor:
Leslie Goo, Pavle S. Milutinovic, Christina R. DeMaso, Kimberly A. Dowd, Theodore C. Pierson, Laura A. VanBlargan, Stephen S. Whitehead, Anna P. Durbin
Publikováno v:
J Virol
Dengue virus cocirculates globally as four serotypes (DENV1 to -4) that vary up to 40% at the amino acid level. Viral strains within a serotype further cluster into multiple genotypes. Eliciting a protective tetravalent neutralizing antibody response
Autor:
Aruna D. De Silva, Alba Grifoni, Angel Balmaseda, Conner K. Kidd, James D. Brien, Stephen S. Whitehead, Hannah Voic, Anna P. Durbin, Alessandro Sette, Eva Harris, Daniela Weiskopf, Sandeep Kumar Dhanda, Anette Stryhn, Søren Buus, Sean A. Diehl
Publikováno v:
J Virol
Members of the flavivirus genus share a high level of sequence similarity and often circulate in the same geographical regions. However, whether T cells induced by one viral species cross-react with other related flaviviruses has not been globally ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d53f89312b3917146627da30d715e0
Autor:
Alexandra M. Ortiz, Samuel J. Magaziner, Erik P. Karmele, Joseph C. Mudd, Jason M. Brenchley, Theodore C. Pierson, Stephen S. Whitehead, Shelly J. Robertson, Heather D. Hickman, Carol L. Vinton, Kimberly A. Dowd, Emerito Amaro-Carambot, Sonja M. Best, Carly E. Starke
Publikováno v:
mBio
mBio, Vol 10, Iss 6, p e02790-19 (2019)
mBio, Vol 10, Iss 6 (2019)
mBio, Vol 10, Iss 6, p e02790-19 (2019)
mBio, Vol 10, Iss 6 (2019)
Immunocompromised individuals often become symptomatic with infections which are normally fairly asymptomatic in healthy individuals. The particular mechanisms that underlie susceptibility to coinfections in human immunodeficiency virus (HIV)-infecte
Autor:
Stephen S. Whitehead, Emerito Amaro-Carambot, Rita E. Chen, Emma S. Winkler, Laura A. VanBlargan, M. Jane Cardosa, Theodore C. Pierson, Kimberly A. Dowd, Nikos Vasilakis, Carlos A. Sariol, David N. Gordon, John M. Errico, Chandni Desai, Daved H. Fremont, Rafick Pierre Sekaly, Esper G. Kallas, Brittany K. Smith, Michael S. Diamond, Scott A. Handley
Publikováno v:
Cell Host Microbe
Although divergent dengue viruses (DENVs) have been isolated in insects, nonhuman primates, and humans, their relationships to the four canonical serotypes (DENV 1-4) are poorly understood. One virus isolated from a dengue patient, DKE-121, falls bet
Autor:
Julie Callison, Dana P. Scott, Andrea Marzi, Nicolette Arndt, Stephen S. Whitehead, Kristin L. McNally, David Safronetz, Spencer Chadinha, Heinz Feldmann, Cynthia Martellaro, Jackson Emanuel, Rebecca Rosenke, Sonja M. Best
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology
The common small animal disease models for Zika virus (ZIKV) are mice lacking the interferon responses, but infection of interferon receptor α/β knock out (IFNAR−/−) mice is not uniformly lethal particularly in older animals. Here we sought to
Autor:
Sebastian P. Fuchs, Diogo M. Magnani, Ronald C. Desrosiers, Maria do Carmo Sampaio Tavares Timenetsky, Priscilla R. Costa, Dennis R. Burton, Nuria Pedreño-Lopez, Martin J. Gutman, Michael J. Ricciardi, Aline Domingues, Jorge Kalil, Mauricio A. Martins, Cassia G. T. Silveira, Jens Wrammert, Helen S. Maxwell, Raphaella Goulart, Esper G. Kallas, José M. Martinez-Navio, David I. Watkins, Lucas Gonzalez-Nieto, Stephen S. Whitehead, Lilian Ferrari, Varian K. Bailey
Exposure to dengue virus (DENV) is thought to elicit lifelong immunity, mediated by DENV-neutralizing antibodies (nAbs). However, Abs generated by primary infections confer serotype-specific protection, and immunity against other serotypes develops o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b886b8dc0b1ff6c8a338e66b0ad4e751
https://europepmc.org/articles/PMC5660501/
https://europepmc.org/articles/PMC5660501/
Autor:
Wen-Yang Tsai, Jih-Jin Tsai, Wei-Kung Wang, Stephen S. Whitehead, Anna P. Durbin, Szu Chia Hsieh
Publikováno v:
Journal of Virology. 89:7348-7362
The four serotypes of dengue virus (DENV) cause the most important and rapidly emerging arboviral diseases in humans. The recent phase 2b and 3 studies of a tetravalent dengue vaccine reported a moderate efficacy despite the presence of neutralizing
Autor:
Mauricio A. Martins, Helen S. Maxwell, Mateus C. Trindade, Vivian Iida Avelino-Silva, Dennis R. Burton, Sebastian P. Fuchs, Martin J. Gutman, José M. Martinez-Navio, Varian K. Bailey, Esper G. Kallas, David I. Watkins, Maurício Lacerda Nogueira, Stephen S. Whitehead, Ronald C. Desrosiers, Juliana Silva Nogueira, Nuria Pedreño-Lopez, Brandon C. Rosen, Diogo M. Magnani, Cassia G. T. Silveira, Alvino Maestri, Aline Domingues, José Eduardo Levi, Alvina Clara Felix, Lucas Gonzalez-Nieto, Michael J. Ricciardi, Consuelo Silva de Oliveira
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005655 (2017)
Repositório Digital do Instituto Evandro Chagas (Patuá)
Instituto Evandro Chagas (IEC)
instacron:IEC
PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Digital do Instituto Evandro Chagas (Patuá)
Instituto Evandro Chagas (IEC)
instacron:IEC
PLoS Neglected Tropical Diseases
PLOS Neglected Tropical Diseases
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The isolation of neutralizing monoclonal antibodies (nmAbs) against the Zika virus (ZIKV) might lead to novel preventative strategies for infections in at-risk individuals, primarily pregnant women. Here we describe the characterization of human mAbs
Autor:
Beth D. Kirkpatrick, Patrick H. O'Rourke, Alba Grifoni, Aruna D. De Silva, Simon Mallal, Sean A. Diehl, Bjoern Peters, Stephen S. Whitehead, Sinu Paul, Anna P. Durbin, Michael A. Angelo, John Sidney, Daniela Weiskopf, Elizabeth J. Phillips, Alessandro Sette
Publikováno v:
Journal of Virology. 91
Dengue virus (DENV) is responsible for growing numbers of infections worldwide and has proven to be a significant challenge for vaccine development. We previously demonstrated that CD8 + T cell responses elicited by a dengue live attenuated virus (DL