Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jingwei Cheng"'
Autor:
Gabriel J. Starrett, Christina Marcelus, Paul G. Cantalupo, Joshua P. Katz, Jingwei Cheng, Keiko Akagi, Manisha Thakuria, Guilherme Rabinowits, Linda C. Wang, David E. Symer, James M. Pipas, Reuben S. Harris, James A. DeCaprio
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Merkel cell polyomavirus is the primary etiological agent of the aggressive skin cancer Merkel cell carcinoma (MCC). Recent studies have revealed that UV radiation is the primary mechanism for somatic mutagenesis in nonviral forms of MCC. He
Externí odkaz:
https://doaj.org/article/897076653c5b47418a7b045c9bff2e0e
Autor:
Jingwei Cheng, Meng Xiao, Timothy Kudinha, Fanrong Kong, Zhipeng Xu, Linying Sun, Li Zhang, Xin Fan, Xiuli Xie, Yingchun Xu
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
While the developed world has seen a significant increase in the number of scientific articles on C. difficile infection (CDI), the developing world still lags behind on this subject due to limited laboratory capacity, low awareness and limited surve
Externí odkaz:
https://doaj.org/article/5b43b3d30c3f4c3dbff2c215e1f5fead
Autor:
Megan E. Spurgeon, Jingwei Cheng, Ella Ward-Shaw, Frederick A. Dick, James A. DeCaprio, Paul F. Lambert
Publikováno v:
PLoS pathogens. 18(5)
Clear evidence supports a causal link between Merkel cell polyomavirus (MCPyV) and the highly aggressive human skin cancer called Merkel cell carcinoma (MCC). Integration of viral DNA into the human genome facilitates continued expression of the MCPy
Publikováno v:
International microbiology : the official journal of the Spanish Society for Microbiology. 23(4)
Purpose Clostridioides difficile toxin B (TcdB) plays a critical role in C. difficile infection (CDI), a common and costly healthcare-associated disease. The aim of the current study was to explore the intracellular and potent systemic effects of Tcd
Autor:
Reety Arora, Peter M. Howley, Christian Berrios, Elizabeth A. White, Tengfei Xiao, Rhamy Zeid, Timothy Branigan, Selene K. Swanson, Thomas Westerling, Jingwei Cheng, Alexander J. Federation, Myles Brown, Michael P. Washburn, James A. DeCaprio, Donglim Esther Park, James E. Bradner, Benjamin J. Strober, Megha Padi, Laurence Florens, Rosa Yoon
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006668 (2017)
PLoS Pathogens
PLoS Pathogens
Merkel cell carcinoma (MCC) frequently contains integrated copies of Merkel cell polyomavirus DNA that express a truncated form of Large T antigen (LT) and an intact Small T antigen (ST). While LT binds RB and inactivates its tumor suppressor functio
Autor:
James M. Pipas, Reuben S. Harris, Joshua P. Katz, Keiko Akagi, James A. DeCaprio, Jingwei Cheng, Christina Marcelus, Linda C. Wang, Guilherme Rabinowits, Manisha Thakuria, Gabriel J. Starrett, Paul G. Cantalupo, David E. Symer
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
mBio, Vol 8, Iss 1, p e02079-16 (2017)
mBio
mBio, Vol 8, Iss 1, p e02079-16 (2017)
mBio
Merkel cell polyomavirus is the primary etiological agent of the aggressive skin cancer Merkel cell carcinoma (MCC). Recent studies have revealed that UV radiation is the primary mechanism for somatic mutagenesis in nonviral forms of MCC. Here, we an
Publikováno v:
Journal of Virology. 87:6118-6126
Merkel cell carcinoma (MCC) is a rare and aggressive form of skin cancer. In at least 80% of all MCC, Merkel cell polyomavirus (MCPyV) DNA has undergone clonal integration into the host cell genome, and most tumors express the MCPyV large and small T
Autor:
Vadim Molla, Donglim Esther Park, James A. DeCaprio, Christian Berrios, John Quackenbush, Megha Padi, Mark A. Keibler, Jingwei Cheng, Gregory Stephanopoulos, Soo Mi Lee
Publikováno v:
PLoS Pathogens
PLoS
PLoS Pathogens, Vol 12, Iss 11, p e1006020 (2016)
PLoS
PLoS Pathogens, Vol 12, Iss 11, p e1006020 (2016)
Merkel cell polyomavirus (MCPyV) is an etiological agent of Merkel cell carcinoma (MCC), a highly aggressive skin cancer. The MCPyV small tumor antigen (ST) is required for maintenance of MCC and can transform normal cells. To gain insight into cellu
Autor:
James A. DeCaprio, Chandra Sekhar Pedamallu, Joonil Jung, Robert L. Garcea, Christian Berrios, Michael Wang, Jingwei Cheng, Blake Primi, Christina Marcelus, Fujiko Duke, Matthew Meyerson
Publikováno v:
J. Virol. 89, 857-862 (2015)
Malawi polyomavirus (MWPyV) is a recently identified human polyomavirus. Serology for MWPyV VP1 indicates that infection frequently occurs in childhood and reaches a prevalence of 75% in adults. The MWPyV small T antigen (ST) binds protein phosphatas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5b1c14518aa3a97d9a683a2cec82bb
https://europepmc.org/articles/PMC4301141/
https://europepmc.org/articles/PMC4301141/
Autor:
Megha Padi, Anna Korkhin, James A. DeCaprio, Robert L. James, Michael A. Calderwood, Rosa Yoon, Jarrod A. Marto, Marc Vidal, Luxuan Guo, Christian Berrios, Ying Zhang, Jingwei Cheng, Soundarapandian Velmurgan, Laurence Florens, Guillaume Adelmant, Michael E. Cusick, Debrah A. Fine, Michael P. Washburn, David E. Hill, Orit Rozenblatt-Rosen, Larisa Litovchick
Publikováno v:
PLoS Pathogens, Vol 8, Iss 10, p e1002949 (2012)
PLoS Pathogens
PLoS Pathogens
The small genome of polyomaviruses encodes a limited number of proteins that are highly dependent on interactions with host cell proteins for efficient viral replication. The SV40 large T antigen (LT) contains several discrete functional domains incl