Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Liyan Fan"'
Autor:
Nikunj Sharma, David R Sweet, Panjamaporn Sangwung, Yoichi Takami, Neelakantan T Vasudevan, Anthony Wynshaw-Boris, Paul Holvoet, Yuan Lu, Liyan Fan, Xudong Liao, Stanton L. Gerson, E. Ricky Chan, Chen Fu, Chloe E Booth, Vinesh Vinayachandran, Guangjin Zhou, Lilei Zhang, Keiichiro Matoba, Yulan Qing, Komal S Keerthy, Mukesh K. Jain, Lalitha Nayak, Derin Tugal
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Substantial evidence implicates crosstalk between metabolic tissues and the immune system in the inception and progression of obesity. However, molecular regulators that orchestrate metaflammation both centrally and peripherally remains incompletely
Autor:
Christopher B. Newgard, Ernest R. Chan, Chloe E Booth, Yuan Lu, Liyan Fan, Vinesh Vinayachandran, Rongli Zhang, Olga Ilkayeva, Mukesh K. Jain, Komal S Keerthy, David R Sweet, Domenick A Prosdocimo
Publikováno v:
J Clin Invest
Skeletal muscle is a major determinant of systemic metabolic homeostasis that plays a critical role in glucose metabolism and insulin sensitivity. By contrast, despite being a major user of fatty acids, and evidence that muscular disorders can lead t
Publikováno v:
J Clin Invest
Chronic glucocorticoid therapy has serious side effects, including diabetes and fatty liver. However, the molecular mechanisms responsible for steroid-induced diabetes remain largely enigmatic. Here, we show that hepatic Krüppel-like factor 9 (Klf9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5760704b51c86d4c4e21c9f22ba47f70
https://europepmc.org/articles/PMC6546472/
https://europepmc.org/articles/PMC6546472/
Autor:
Browning Haynes, Domenick A. Prosdocimo, Megan Pophal, Mukesh K. Jain, Shamanthika Shelkay, Palvir K. Baadh, Liyan Fan, Olga Ilkayeva, Bridget Moroney, Paishiun N. Hsieh, Christopher B. Newgard, Keiki Sugi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0192376 (2018)
PLoS ONE, Vol 13, Iss 2, p e0192376 (2018)
Cardiac metabolism is highly adaptive in response to changes in substrate availability, as occur during fasting. This metabolic flexibility is essential to the maintenance of contractile function and is under the control of a group of select transcri
Autor:
Jie Fan, Melanie J. Scott, Xiaolian Shi, Timothy R. Billiar, Shilai Li, Mark Wilson, Liyan Fan, Quan Liu, Guozhi Xiao, Juan Wang, Z Liu, Jia Xu, Yuehua Li, Yiguo Jiang
Publikováno v:
Cell Death & Differentiation. 21:1229-1239
Macrophages can be activated and regulated by high-mobility group box 1 (HMGB1), a highly conserved nuclear protein. Inflammatory functions of HMGB1 are mediated by binding to cell surface receptors, including the receptor for advanced glycation end
Autor:
Melanie J. Scott, Meng Xiang, Zongmei Wen, Yuehua Li, Mark Wilson, Guozhi Xiao, Xueyin Shi, Song Li, Timothy R. Billiar, Peng Xu, Liyan Fan, Aijun Li, Jie Fan
Publikováno v:
The Journal of Immunology. 190:5247-5255
Hemorrhagic shock (HS) promotes the development of systemic inflammatory response syndrome and organ injury by activating and priming the innate immune system for an exaggerated inflammatory response through, as of yet, unclear mechanisms. IL-1β als
Autor:
Yoram Vodovotz, Juan Wang, Ruben Zamora, Mark Wilson, Zheng Liu, Yong Jiang, Yuehua Li, Rami A. Namas, Liyan Fan, Timothy R. Billiar, Derek Barclay, Jie Fan
Publikováno v:
The FASEB Journal
Trauma/hemorrhagic shock is associated with morbidity and mortality due to dysregulated inflammation, which is driven in part by monocytes/macrophages stimulated by injury-induced release of damage-associated molecular pattern (DAMP) molecules. MRP8/
Autor:
Melanie J. Scott, Zui Zou, Jie Fan, Guozhi Xiao, Song Li, Mark Wilson, Zongmei Wen, Xueyin Shi, Timothy R. Billiar, Liyan Fan, Yuehua Li
Acute lung injury (ALI) is a major component of multiple organ dysfunction syndrome after hemorrhagic shock (HS) resulting from major surgery and trauma. The increased susceptibility in HS patients to the development of ALI suggests not yet fully elu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5326da875ae66e5744bf0ed14fa2d385
https://europepmc.org/articles/PMC4201969/
https://europepmc.org/articles/PMC4201969/
Autor:
Melanie J. Scott, Aijun Li, Jie Fan, Timothy R. Billiar, Yuehua Li, Youzhong Yuan, Lianhua Yin, Liyan Fan, Guozhi Xiao, Meng Xiang, Mark Wilson
Publikováno v:
Shock (Augusta, Ga.). 37(5)
The release of hematopoietic progenitor cells (HPCs) from bone marrow (BM) is under tight homeostatic control. Under stress conditions, HPCs migrate from BM and egress into circulation to participate in immune response, wound repair, or tissue regene