Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karen J. Keeran"'
Autor:
Mehdi Pirooznia, Komudi Singh, Marjan Gucek, Danielle A. Springer, Matthew E. Cockman, Angel Aponte, Junhui Sun, Karen J. Keeran, Elizabeth Murphy, Michael Harris, Leslie Kennedy
Publikováno v:
Cardiovasc Res
AIMS Prolyl hydroxylation is a post-translational modification that regulates protein stability, turnover, and activity. The proteins that catalyze prolyl hydroxylation belong to the 2-oxoglutarate- and iron-dependent oxygenase family of proteins. 2-
Autor:
Maryann Kaler, Xianglan Yao, Stewart J. Levine, Angel Aponte, Kenneth R. Jeffries, Marjan Gucek, Xuan Qu, Katharine S. Meyer, Rosemarie A. Cuento, Elizabeth M. Gordon, Karen J. Keeran, McCoy Jp, Gayle Z. Nugent, Amisha V. Barochia, Pradeep K. Dagur, Zu-Xi Yu, Cuilian Dai
Publikováno v:
Mucosal immunology
CD163 is a macrophage scavenger receptor with anti-inflammatory and pro-inflammatory functions. Here, we report that alveolar macrophages (AMΦs) from asthmatic subjects had reduced cell-surface expression of CD163, which suggested that CD163 might m
Autor:
Meixia Gao, Zu-Xi Yu, Xuan Qu, Katharine S. Meyer, Xianglan Yao, Jichun Chen, Cuilian Dai, Stewart J. Levine, Pradeep K. Dagur, Gayle Z. Nugent, Karen J. Keeran, J. Philip McCoy
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 49:902-911
Peptidoglycan recognition protein (Pglyrp) 1 is a pattern-recognition protein that mediates antibacterial host defense. Because we had previously shown that Pglyrp1 expression is increased in the lungs of house dust mite (HDM)-challenged mice, we hyp
Autor:
J. Philip McCoy, Kenneth R. Jeffries, Jay H. Chung, Zu-Xi Yu, Shutong Yang, Xuan Qu, Xianglan Yao, Gayle Z. Nugent, Alexandra L. Brown, Sung-Jun Park, Stewart J. Levine, Amarjit Mishra, Karen J. Keeran, Chengyu Liu, Pradeep K. Dagur
Publikováno v:
Nature communications
DNA-dependent protein kinase (DNA-PK) mediates double stranded DNA break repair, V(D)J recombination, and immunoglobulin class switch recombination, as well as innate immune and pro-inflammatory responses. However, there is limited information regard
Autor:
Stewart J. Levine, Zu-Xi Yu, Xianglan Yao, Xuan Qu, Amarjit Mishra, Karin Fredriksson, Pradeep K. Dagur, Jonathan Lam, Gayle Z. Nugent, Katharine S. Meyer, Yanqin Yang, Karen J. Keeran, Elizabeth M. Mushaben, Nalini Raghavachari, J. Philip McCoy, Rosemarie A. Cuento
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(10)
The very low density lipoprotein receptor (VLDLR) is a member of the low-density lipoprotein receptor family that binds multiple ligands and plays a key role in brain development. Although the VLDLR mediates pleiotropic biological processes, only a l
Autor:
Minjung Kwak, Stewart J. Levine, Marcelo Amar, Karin Fredriksson, Xiuli Xu, Zu-Xi Yu, Karen J. Keeran, Gayle J. Zywicke, Xianglan Yao, Nalini Raghavachari, Alan T. Remaley
Publikováno v:
American journal of respiratory and critical care medicine. 182(10)
Rationale: Distinct sets of corticosteroid-unresponsive genes modulate disease severity in asthma. Objectives: To identify corticosteroid-unresponsive genes that provide new insights into disease pathogenesis and asthma therapeutics. Methods: Experim